Terbinafine is an oral anti-fungal agent used to treat onychomycosis, which is a fungal infection of the nails. Oral terbinafine has been demonstrated to be the most effective treatment for the mycological cure of toenail fungal infections. Terbinafine works by inhibiting squalene epoxidase, the enzyme in fungal cells that convert squalene to squalene epoxide. This results in an intracellular accumulation of squalene and results in fungal cell death.
- Suitable in patients already taking this therapy under supervision of their medical doctor or provider
- Typical dosing is 250 mg once daily for 6 weeks (fingernail) or 12 weeks (toenail)
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Terbinafine Medication Description
Terbinafine is a prescription oral antifungal medication used to treat onychomycosis, a fungal infection of the fingernails or toenails. It works by inhibiting squalene epoxidase, an enzyme essential for fungal cell membrane production. This disruption causes a buildup of squalene inside the fungal cell, leading to cell death and clearance of the infection.
Oral terbinafine has been shown to be one of the most effective treatments for achieving a complete mycological cure in toenail fungal infections. Treatment duration depends on whether fingernails or toenails are affected.
Usage Instructions
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Take exactly as prescribed by your healthcare provider, usually once daily
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Continue therapy for the full duration prescribed, even if nail appearance improves before treatment is complete
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Fingernail infections are typically treated for 6 weeks; toenail infections for 12 weeks
Warnings & Precautions
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Use only under medical supervision, especially if you have liver disease or a history of liver problems
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Your provider may order blood tests to monitor liver function during treatment
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Possible side effects include headache, diarrhea, stomach upset, rash, or changes in taste
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Seek medical attention if you experience persistent nausea, fatigue, dark urine, or yellowing of the skin or eyes, as these may be signs of liver damage
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Inform your healthcare provider of all medications you take, as terbinafine may interact with certain drugs
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Terbinafine Side Effects
Terbinafine side effects may include headache, diarrhea, skin rash, itching, altered senses of taste or smell.
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Consumer Information Use and Disclaimer
This information should not be used to decide whether or not to take this medicine or any other medicine. Only a healthcare provider has the knowledge and training to decide which medicines are right for you. TelyRx does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a limited summary of general information about the medicine’s uses from the patient education materials and is not intended to be comprehensive. This limited summary does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not intended to provide medical advice, diagnosis or treatment and does not replace information you may receive from your healthcare provider. For a more detailed summary of information about the risks and benefits of using this medicine, please review the entire patient education information you receive with the medication.
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