Skin & Hair

Spironolactone

Generic For Aldactone

starting at $24.99

Spironolactone may be used to treat moderate to severe acne in females. Use of treatment for acne in males is typically avoided to the antiandrogen blocking activity of this medication.

Used for moderate to severe acne treatment in females

Initial dosing of 25 mg daily, and can be increased as needed based on response

Must be taken consistently with or without food, and must avoid high potassium foods, such as potassium containing salt substitutes, bananas, nuts, and certain leafy greens

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HSA/FSA Eligible

Spironolactone

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Spironolactone

Spironolactone may be used to treat moderate to severe acne in females. Use of treatment for acne in males is typically avoided to the antiandrogen blocking activity of this medication.

By clicking the “I Agree” button below, you certify under penalty of perjury that the following statements are true and correct and understand that a medical provider will rely on the truthfulness of your statements when determining whether a prescription is warranted and appropriate.

I agree that I:

am 18 years or older
have not had a hypersensitivity reaction to spironolactone or any component of the formulation
do not have a high potassium level (hyperkalemia), Addison’s disease, and am not taking eplerenone
am not taking a blood pressure medication in the classes angiotensin receptor blocker (ARB) or angiotensin converting enzyme inhibitor (ACEI). Examples of these medications are losartan, valsartan, olmesartan, lisinopril, enalapril, and ramipril.
am not pregnant or breastfeeding
do not have heart failure or liver cirrhosis
do not have a history of liver (hepatic) or kidney (renal) impairment (CrCl<30 mL/minute)
understand this medication can increase potassium levels and may cause electrolyte and fluid imbalances
will discontinue the use of this medication if receiving adrenal vein catheterization
have already been taking the initial dose (spironolactone 25 mg) or preceding dose (spironolactone 50 mg) or have been previously prescribed the higher dose if selecting spironolactone 50 mg or 100 mg
understand this is not a comprehensive list of precautions, risks, side effects, or details about taking this medication
understand that only major drug interactions are listed and have not been reviewed against the other medications, supplements, or herbal products I may be taking unless also filled by TelyRx

understand that TelyRx LLC does not provide medical care and the providers who use TelyRx to provide telehealth services (“Telehealth Providers”) should not replace your primary provider.
understand that the Telehealth Providers are not able to: (1) monitor ongoing health or lab values for side effects or efficacy, (2) observe how you (or your pet) tolerate any prescribed treatment, or (3) determine if the prescribed treatment is working as intended and assume any risks associated with this modality of care and waive any claim I may have in the future against TelyRx and/or the Telehealth Providers.
understand that by using this site, I have created a patient-client-doctor relationship and I am being directed by the Telehealth Providers to consult my primary provider soon after beginning any treatment prescribed by the Telehealth Providers.
understand that this is a supplemental mode of care for your convenience and the Telehealth Providers are not to be used, or relied on, as a replacement for in-person follow-up visits or interactions with your primary provider.

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Spironolactone Medication Description
Spironolactone tablets (Aldactone®) are a prescription medication that belong to a class of drugs called potassium-sparing diuretics, also known as aldosterone antagonists. They are FDA-approved to treat conditions such as high blood pressure, heart failure, and fluid retention (edema) caused by liver cirrhosis, kidney disease, or other medical problems. Spironolactone works by blocking the effects of aldosterone, a hormone that causes the body to retain salt and water. This action helps the body eliminate excess fluid while conserving potassium.

In addition to its approved uses, spironolactone is often prescribed off-label for hormonal acne and in women with polycystic ovary syndrome (PCOS) to help reduce symptoms such as acne, excess hair growth, and irregular menstrual cycles.

How to Use
- Typically prescribed as one or more tablets taken once or twice daily, with food to reduce stomach irritation.
- Dosages vary widely depending on the condition being treated:
- High blood pressure: often 25–100 mg daily.
- Heart failure or edema: doses may be higher, as directed by a healthcare provider.
- Hormonal acne/PCOS: often prescribed at lower doses, commonly 50–100 mg daily.
- Tablets should be swallowed whole with water.
- Take spironolactone exactly as prescribed; do not adjust the dose without medical guidance.
Important Notes and Warnings
- Common side effects may include dizziness, stomach upset, breast tenderness, irregular periods, or increased urination.
- Because spironolactone is potassium-sparing, it can raise potassium levels in the blood (hyperkalemia). Patients should avoid potassium supplements, salt substitutes containing potassium, or very high-potassium diets unless approved by a provider.
- Blood tests to monitor potassium and kidney function are often recommended during treatment.
- Inform your healthcare provider if you have kidney disease, liver disease, or adrenal gland disorders before starting therapy.
- Rare but serious side effects may include severe electrolyte imbalances, abnormal heart rhythms, or allergic reactions.
- Spironolactone should not be used during pregnancy due to potential risks to the fetus. Breastfeeding patients should discuss risks and benefits with their provider.
Spironolactone Side Effects

Side effects may include headache, diarrhea, dizziness, and stomach cramps. More severe side effects may include breast pain, menstrual changes, and enlarged breasts in males.
Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only a healthcare provider has the knowledge and training to decide which medicines are right for you. TelyRx does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a limited summary of general information about the medicine’s uses from the patient education materials and is not intended to be comprehensive. This limited summary does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not intended to provide medical advice, diagnosis or treatment and does not replace information you may receive from your healthcare provider. For a more detailed summary of information about the risks and benefits of using this medicine, please review the entire patient education information you receive with the medication.