Promethazine

Digestive & Travel

Promethazine

Generic For Phenergan

starting at $19.99

Promethazine is an antiemetic used to prevent and treat motion sickness. Promethazine is also used to prevent and control nausea and/or vomiting. Promethazine is also a first-generation antihistamine, indicated for various allergic conditions, including seasonal allergies, allergic conjunctivitis, and uncomplicated skin manifestations of hives.

Promethazine is used to prevent and control nausea and/or vomiting.

Take with food, water, or milk to decrease gastrointestinal discomfort

Suitable in patients already taking this therapy

HSA/FSA Eligible

H&P Certification

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Promethazine

By clicking the “I Agree” button below, you certify under penalty of perjury that the following statements are true and correct and understand that a medical provider will rely on the truthfulness of your statements when determining whether a prescription is warranted and appropriate.

I agree that I:

am between the ages of 18 and 65 years
have not had a hypersensitivity or idiosyncratic reaction to promethazine, other phenothiazines, or any component of the formulation
Am not in a comatose state nor intend on administering to a patient in a comatose state
Am not taking promethazine for the treatment of lower respiratory tract symptoms including asthma
Am not going to use in children less than 2 years of age
Am not going to administer inter-arterially or subcutaneously or administer intravenously at concentrations greater than 1 mg/ml
have already been using promethazine as prescribed by an authorized healthcare provider
am not pregnant or breastfeeding
Do not have liver disease or impairment
Understand promethazine should not be used in pediatric patients younger than 2 years of age because of the potential for fatal respiratory depression
Understand promethazine can cause severe chemical irritation and tissue damage when administered as an injection
Understand promethazine is listed in the Beers Criteria as a potentially inappropriate medication to be avoided in patients 65 years and older (independent of diagnosis or condition) due to its potent anticholinergic properties resulting in increased risk of confusion, dry mouth, constipation, and other toxicities.
Understand the use of promethazine may aggravate the following medical conditions and should be used with caution: bone marrow suppression, cardiovascular disease, GI motility, glaucoma, hepatic impairment, myasthenia gravis, Parkinson disease, conditions of compromised respiratory function such COPD or sleep apnea, urinary retention, benign prostatic hyperplasia (BPH), or bladder neck obstruction
Understand promethazine may cause anticholinergic adverse effects such as blurred vision, confusion, constipation, dry eye, urinary retention, and dry mouth
Understand promethazine has been associated with dizziness, drowsiness, delirium, motor dysfunction (motor sensory instability), and sedated state in adult and pediatric patients
Understand extrapyramidal reactions (EPS), including akathisia (i.e., inability to remain still), acute dystonia, drug-induced parkinsonism, and tardive dyskinesia, have occurred with the use of promethazine in adult and pediatric patients
Understand promethazine may cause orthostatic hypotension which may increase the risk for falls in older patients; this risk may be augmented by the sedative effects of promethazine
Understand promethazine may intensify, increase, or prolong the sedative action of other CNS depressants, such as tricyclic antidepressants, sedatives/hypnotics, narcotics, narcotic analgesics, alcohol, general anesthetics, and tranquilizers; therefore, those medicines should be avoided when taking promethazine
Will not take nor intend to take the following concurrently with promethazine: aclidinium, aminolevulinic acid, nasal azelastine, blonanserin, bromopride, bromperidol, buprenorphine, chlormethiazole, cimetropium, clozapine, daridorexant, dexmedetomidine, droperidol, eluxadoline, epinephrine, flunarizine, flunitrazepam, glycopyrrolate oral inhalation, glycopyrronium topical, hydroxyzine, ipratropium oral inhalation, kratom, lemborexant, levosulpiride, loxapine, methotrimeprazine, metoclopramide, nabilone, nasal olopatadine, opioid agonists, orphenadrine, oxatomide, oxomemazine, oxybate salt products, oxycodone, paraldehyde, pitolisant, potassium chloride, potassium citrate, pramlintide, revefenacin, rivastigmine, ropeginterferon alfa-2b, secretin, suvorexant, thalidomide, tiotropium, tranylcypromine, umeclidinium, zolpidem, zuranolone
understand this is not a comprehensive list of severe or major drug interactions and I can find more information regarding drug-drug interactions at https://www.drugs.com/drug_interactions.html
Understand there is a black box warning in which severe chemical irritation and damage to tissues has been reported, regardless of parenteral route of administration, of promethazine injection including gangrene, tissue necrosis, and thrombophlebitis
understand this is not a comprehensive list of precautions, risks, side effects, or details about taking this medication
understand that only major drug interactions are listed and have not been reviewed against the other medications, supplements, or herbal products I may be taking unless also filled by TelyRx

understand that TelyRx LLC does not provide medical care and the providers who use TelyRx to provide telehealth services (“Telehealth Providers”) should not replace your primary provider.
understand that the Telehealth Providers are not able to: (1) monitor ongoing health or lab values for side effects or efficacy, (2) observe how you (or your pet) tolerate any prescribed treatment, or (3) determine if the prescribed treatment is working as intended and assume any risks associated with this modality of care and waive any claim I may have in the future against TelyRx and/or the Telehealth Providers.
understand that by using this site, I have created a patient-client-doctor relationship and I am being directed by the Telehealth Providers to consult my primary provider soon after beginning any treatment prescribed by the Telehealth Providers.
understand that this is a supplemental mode of care for your convenience and the Telehealth Providers are not to be used, or relied on, as a replacement for in-person follow-up visits or interactions with your primary provider.

I agree that all statements above are true and my physician visit is complete.

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Promethazine Medication Description

Promethazine is a prescription medication that functions as both an antiemetic and a first-generation antihistamine. It is used to prevent and treat motion sickness, as well as to control nausea and vomiting from various causes, including after surgery or during illness. In addition, promethazine is indicated for relief of allergic conditions such as seasonal allergies, allergic conjunctivitis, and uncomplicated skin reactions like hives.

By blocking histamine receptors in the body, promethazine helps reduce allergy symptoms such as sneezing, itching, watery eyes, and skin irritation. Its antiemetic properties work by affecting the brain’s vomiting center, making it effective for nausea prevention and relief.

Usage Instructions

• Take exactly as prescribed by your healthcare provider

• May be taken with food, water, or milk to reduce stomach upset

• For motion sickness, take the first dose 30–60 minutes before travel or as directed by your provider

• Avoid alcohol while taking promethazine, as it can increase drowsiness

Warnings & Precautions

• May cause marked drowsiness; use caution when driving or operating machinery

• Avoid alcohol and other central nervous system depressants while taking this medication

• Use with caution in patients with glaucoma, breathing disorders, seizure disorders, or liver disease

• May cause side effects such as dry mouth, blurred vision, constipation, or dizziness

• Inform your healthcare provider if you are pregnant, breastfeeding, or taking other sedating medications
Promethazine Side Effects

Promethazine side effects may include fatigue, blurred vision, dry mouth, nausea, vomiting, trouble sleeping, constipation, urinary retention, dizziness, drowsiness
Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only a healthcare provider has the knowledge and training to decide which medicines are right for you. TelyRx does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a limited summary of general information about the medicine’s uses from the patient education materials and is not intended to be comprehensive. This limited summary does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not intended to provide medical advice, diagnosis or treatment and does not replace information you may receive from your healthcare provider. For a more detailed summary of information about the risks and benefits of using this medicine, please review the entire patient education information you receive with the medication.