Promethazine is a prescription medication that functions as both an antiemetic and a first-generation antihistamine. It is used to prevent and treat motion sickness, as well as to control nausea and vomiting from various causes, including after surgery or during illness. In addition, promethazine is indicated for relief of allergic conditions such as seasonal allergies, allergic conjunctivitis, and uncomplicated skin reactions like hives.
By blocking histamine receptors in the body, promethazine helps reduce allergy symptoms such as sneezing, itching, watery eyes, and skin irritation. Its antiemetic properties work by affecting the brain’s vomiting center, making it effective for nausea prevention and relief.
Usage Instructions
• Take exactly as prescribed by your healthcare provider
• May be taken with food, water, or milk to reduce stomach upset
• For motion sickness, take the first dose 30–60 minutes before travel or as directed by your provider
• Avoid alcohol while taking promethazine, as it can increase drowsiness
Warnings & Precautions
• May cause marked drowsiness; use caution when driving or operating machinery
• Avoid alcohol and other central nervous system depressants while taking this medication
• Use with caution in patients with glaucoma, breathing disorders, seizure disorders, or liver disease
• May cause side effects such as dry mouth, blurred vision, constipation, or dizziness
• Inform your healthcare provider if you are pregnant, breastfeeding, or taking other sedating medications