Progesterone is a female hormone used to help prevent endometrial hyperplasia associated with estrogen therapy. Endometrial hyperplasia is a precancerous condition in which there is an irregular thickening of the uterine lining. This may cause uncomfortable symptoms for women, including heavy menstrual periods, postmenopausal bleeding, and anemia due to the excess bleeding.
- Used to lower the chance of endometrial changes after menopause in people who are getting estrogen therapy
- Must be 60 years of age or younger or within 10 years of menopause
- Must be currently using estrogen therapy and have an intact uterus
- May be administered either cyclically (200mg once daily for 12 days each month) or continuously (100mg daily)
- Suitable for patients already taking this medication
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Progesterone Capsules Medication Description
Progesterone is a naturally occurring female hormone used to help prevent endometrial hyperplasia, a precancerous thickening of the uterine lining, in individuals receiving estrogen therapy after menopause. Estrogen alone can stimulate the uterine lining and increase the risk of abnormal changes. By balancing estrogen’s effects, progesterone helps protect the endometrium, reducing the risk of heavy bleeding, postmenopausal spotting, and related complications such as anemia.
Progesterone capsules are generally prescribed for postmenopausal individuals with an intact uterus who are receiving systemic estrogen therapy. Treatment may be given on a cyclical schedule or as continuous daily therapy, depending on patient needs and provider recommendations.
Usage Instructions
• Take exactly as prescribed by your healthcare provider
• May be administered cyclically or continuously
• Swallow capsules whole with a full glass of water, with or without food
• Take at the same time each day to maintain consistent hormone levels
• Follow your provider’s instructions on timing in relation to estrogen therapy
Warnings & Precautions
• For use only in individuals with an intact uterus who are receiving estrogen therapy
• Not intended for use in pregnancy. Inform your provider if you may be pregnant or breastfeeding
• May cause dizziness, headaches, bloating, or breast tenderness
• Use with caution if you have a history of blood clots, liver disease, certain cancers, or cardiovascular disease
• Report any unusual vaginal bleeding promptly, as it may indicate a more serious condition
• Hormone therapy should be used for the shortest duration necessary to meet treatment goals
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Progesterone Capsules Side Effects
Progesterone capsules side effects may include sudden severe headache, unusual vaginal bleeding, mental or mood changes, swelling of the hands or feet, breast lumps or yellowing of the eyes or skin.
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Consumer Information Use and Disclaimer
This information should not be used to decide whether or not to take this medicine or any other medicine. Only a healthcare provider has the knowledge and training to decide which medicines are right for you. TelyRx does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a limited summary of general information about the medicine’s uses from the patient education materials and is not intended to be comprehensive. This limited summary does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not intended to provide medical advice, diagnosis or treatment and does not replace information you may receive from your healthcare provider. For a more detailed summary of information about the risks and benefits of using this medicine, please review the entire patient education information you receive with the medication.
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