Digestive & Travel

Pantoprazole Tablets

Generic For Protonix

starting at $19.99

Pantoprazole is a proton pump inhibitor that is used to treat severe acid reflux (i.e. GERD) that is not adequately treated with other medications. It is typically taken once daily until symptoms are controlled, then continued for at least 8 weeks.

Used to treat acid reflux symptoms including heartburn, acid indigestion, and upset stomach occurring more than 2 days per week

Typical dosing for recurring acid reflux is 40 mg once daily until symptoms are controlled, then continued for at least 8 weeks

Recommended to be taken on an empty stomach, 30 to 60 minutes before breakfast

If symptoms persist after pantoprazole use, gradual decrease in dosing and referral to a specialist is recommended

Long-term maintenance therapy with 40 mg once daily is recommended for patients with erosive esophagitis or Barrett esophagus

HSA/FSA Eligible

Pantoprazole Tablets

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Pantoprazole Tablets

I agree that I:

Am 18 years or older
Have not had a hypersensitivity reaction to pantoprazole, other proton pump inhibitors (e.g. omeprazole, lansoprazole) or any component of its formulation
Am not taking rilpivirine or clopidogrel
Have already been taking pantoprazole for the treatment of gastroesophageal reflux disease
Am not pregnant or breastfeeding
Understand pantoprazole may cause iron and vitamin B12 deficiencies, most often with long-term use (1 year or longer)
Understand this medication may cause low magnesium levels, especially in patients also taking diuretics (e.g., furosemide, hydrochlorothiazide), which can affect the heart and reduce the seizure threshold
Understand this medication increases the risk of infection from Clostridioides difficile (C. diff), bone loss and fractures
Understand pantoprazole does not relieve disease from gastric malignancy
Understand this medication is not suitable for individuals with frequent chest pain, wheezing, nausea and vomiting, and unexplained weight loss
Understand this medication increases the risk of reversible subacute cutaneous lupus erythematosus (SCLE) and reversible gastric polyps
Understand this medication increases the risk of acute interstitial nephritis (AIN)
understand this is not a comprehensive list of precautions, risks, side effects, or details about taking this medication
understand that only major drug interactions are listed and have not been reviewed against the other medications, supplements, or herbal products I may be taking unless also filled by TelyRx

understand that TelyRx LLC does not provide medical care and the providers who use TelyRx to provide telehealth services (“Telehealth Providers”) should not replace your primary provider.
understand that the Telehealth Providers are not able to: (1) monitor ongoing health or lab values for side effects or efficacy, (2) observe how you (or your pet) tolerate any prescribed treatment, or (3) determine if the prescribed treatment is working as intended and assume any risks associated with this modality of care and waive any claim I may have in the future against TelyRx and/or the Telehealth Providers.
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Pantoprazole Medication Description
Pantoprazole tablets (Protonix®) are a prescription medication commonly prescribed to reduce excess stomach acid. They belong to the drug class known as proton pump inhibitors (PPIs) and are FDA-approved for the treatment of gastroesophageal reflux disease (GERD), healing erosive esophagitis, and long-term treatment of conditions associated with excessive acid production such as Zollinger-Ellison syndrome. By blocking the enzyme in the stomach that produces acid, pantoprazole helps relieve heartburn, heal irritation of the esophagus, and prevent acid-related complications.

Pantoprazole tablets are typically prescribed when lifestyle changes and over-the-counter medications are not sufficient to control symptoms. Many patients notice relief within a few days of starting therapy, but full healing of the esophagus may take several weeks.

How to Use
- Often prescribed as one 20mg or one 40 mg tablet taken once daily, with or without food.
- Tablets should be swallowed whole; they should not be split, chewed, or crushed.
- For GERD, treatment is typically prescribed for up to 8 weeks, although some patients may require longer therapy if symptoms persist.
- For conditions such as Zollinger-Ellison syndrome, higher or more frequent dosing may be prescribed under medical supervision.
- Always take pantoprazole exactly as directed by your healthcare provider and complete the full course of treatment, even if symptoms improve.
Important Notes and Warnings
- Pantoprazole is generally well tolerated, but common side effects may include headache, diarrhea, nausea, stomach pain, or gas.
- Long-term use of proton pump inhibitors has been associated with risks such as vitamin B12 deficiency, low magnesium levels, bone fractures, and an increased risk of certain infections (e.g., Clostridioides difficile–associated diarrhea).
- Patients should inform their healthcare provider of all medications they are taking, especially blood thinners (such as warfarin), methotrexate, or HIV medications, as pantoprazole may interact with these.
- Inform your healthcare provider if you are pregnant, planning pregnancy, or breastfeeding before starting pantoprazole.
- Do not stop taking pantoprazole suddenly without medical guidance, as symptoms may return.
Pantoprazole Side Effects

Side effects may include headache, diarrhea, upset stomach, stomach pain, and gas.
Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only a healthcare provider has the knowledge and training to decide which medicines are right for you. TelyRx does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a limited summary of general information about the medicine’s uses from the patient education materials and is not intended to be comprehensive. This limited summary does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not intended to provide medical advice, diagnosis or treatment and does not replace information you may receive from your healthcare provider. For a more detailed summary of information about the risks and benefits of using this medicine, please review the entire patient education information you receive with the medication.