Ozempic® (semaglutide) is a once-weekly injectable medication used to improve blood sugar control in adults with type 2 diabetes and to reduce the risk of major cardiovascular events such as heart attack or stroke in people with both type 2 diabetes and known heart disease. It belongs to a class of drugs known as GLP-1 receptor agonists, which work by mimicking a natural hormone that stimulates insulin release, reduces the amount of sugar produced by the liver, and slows down digestion to help with appetite control. Ozempic® may also lead to weight loss, making it a beneficial option for people managing both diabetes and obesity. *This product is not eligible for discount*
- A once weekly semaglutide injection used off-label for weight loss in combination with diet and exercise
- Dosing begins at 0.25 mg once weekly for 4 weeks then increased to 0.5 mg weekly
- Dose titration can be delayed based on tolerance or further increased to a max of 2 mg weekly as needed
- Injected at least 30 minutes before the first meal, beverage, and other medications
- Must be stored at refrigerated temperatures (2°C to 8°C) or at room temperature for up to 56 days (59°F to 86°F)
- 1 injectable pen = 4 doses or 30 day supply
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Ozempic Medication Description
Ozempic® (semaglutide) is a prescription medication administered once weekly as a subcutaneous injection. It is FDA-approved to help improve blood sugar control in adults with type 2 diabetes and to reduce the risk of major cardiovascular events such as heart attack, stroke, or death in those with type 2 diabetes and existing heart disease. By acting like the natural hormone GLP-1, Ozempic helps the body release insulin when blood sugar is high, decreases glucagon (a hormone that raises blood sugar), and slows digestion. These combined actions help smooth out blood sugar levels after meals and support better long-term control.
In addition to its diabetes indication, Ozempic is sometimes prescribed off-label for weight management. Many patients report reduced appetite and lower food intake while taking the medication, which, along with healthy diet and exercise, can lead to meaningful weight loss. Patients often find the once-weekly injection schedule convenient to fit into their routine.
How to Use
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Typically prescribed as a once-weekly injection given on the same day each week, with or without food.
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Treatment often begins at 0.25 mg once weekly for 4 weeks, then increases to 0.5 mg once weekly.
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If additional blood sugar control is needed, the dose may be increased gradually up to 1 mg or 2 mg once weekly.
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Injections can be given in the abdomen, thigh, or upper arm. Rotate sites with each dose.
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Always use a new needle for each injection.
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Your healthcare provider will determine the exact dosing schedule that is right for you.
Black Box Warning
Ozempic® (semaglutide) carries a boxed warning for the risk of thyroid C-cell tumors. It should not be used in patients with a personal or family history of medullary thyroid carcinoma (MTC) or in those with multiple endocrine neoplasia syndrome type 2 (MEN 2). Patients should promptly report any symptoms such as a lump or swelling in the neck, hoarseness, difficulty swallowing, or shortness of breath.
Important Notes and Warnings
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Ozempic is not indicated for patients with type 1 diabetes or diabetic ketoacidosis.
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The most common side effects include nausea, vomiting, diarrhea, constipation, or abdominal pain, especially during the first few weeks or after a dose increase. These symptoms often improve with continued use.
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Low blood sugar (hypoglycemia) may occur if Ozempic is used in combination with insulin or sulfonylurea medications.
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Patients who are pregnant, planning pregnancy, or breastfeeding should discuss potential risks with their provider.
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Because Ozempic slows stomach emptying, it may affect how other oral medications are absorbed. Your healthcare provider may give guidance on timing other medicines.
Storage
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Store unused pens in the refrigerator between 36°F to 46°F (2°C to 8°C).
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After the first use, pens may be stored at room temperature between 59°F to 86°F (15°C to 30°C) for up to 56 days.
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Ozempic Side Effects
Side effects include injection site reactions, constipation, diarrhea, and stomach pain.
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Consumer Information Use and Disclaimer
This information should not be used to decide whether or not to take this medicine or any other medicine. Only a healthcare provider has the knowledge and training to decide which medicines are right for you. TelyRx does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a limited summary of general information about the medicine’s uses from the patient education materials and is not intended to be comprehensive. This limited summary does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not intended to provide medical advice, diagnosis or treatment and does not replace information you may receive from your healthcare provider. For a more detailed summary of information about the risks and benefits of using this medicine, please review the entire patient education information you receive with the medication.
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