Chronic Conditions
Alendronate Tablets
Generic For Fosamax®
starting at $29.99

Alendronate is a medication commonly prescribed to treat and prevent osteoporosis in postmenopausal women and to increase bone mass in men with osteoporosis. It belongs to a class of drugs known as bisphosphonates, which work by inhibiting osteoclast activity—the cells responsible for breaking down bone tissue. By slowing bone loss, alendronate helps maintain bone strength, reducing the risk of fractures, particularly in the spine and hip. Alendronate must be taken on an empty stomach with a full glass of water, and patients should remain upright for at least 30 minutes afterward to prevent irritation or damage to the esophagus.

  • Alendronate is a bisphosphonate used to treat and prevent bone loss associated with osteoporosis and other bone disorders
  • It works by inhibiting osteoclasts, the cells that break down bone tissue, helping to maintain or increase bone density
  • Approved uses include treatment and prevention of osteoporosis in postmenopausal women, osteoporosis in men, and steroid-induced bone loss
  • Alendronate must be taken first thing in the morning with a full glass of water, at least 30 minutes before food or other medications
  • Patients should remain upright for at least 30 minutes after taking it to avoid esophageal irritation or ulcers
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  • Alendronate Tablet Side Effects

    Alendronate tablets side effects may include the following: 

    Common side effects often involve the digestive system and may include abdominal pain, acid reflux, constipation, diarrhea, or nausea. Some people experience mild musculoskeletal pain, such as joint or back pain. Headache and dizziness may also occur.

    Less common but more serious side effects include esophagitis (inflammation of the esophagus), esophageal ulcers, and difficulty swallowing, especially if the medication is not taken exactly as instructed. Rarely, alendronate may cause osteonecrosis of the jaw, particularly following dental surgery or in patients with cancer or poor oral hygiene. Another rare but serious effect is atypical femur fractures, which can happen with long-term use and minimal or no trauma.

    Patients are advised to report any new or worsening bone, joint, or thigh pain, as well as any difficulty or pain when swallowing, chest pain, or heartburn, which may signal more serious complications. Staying upright and following all administration instructions can help reduce the risk of gastrointestinal side effects.

  • Consumer Information Use and Disclaimer

    This information should not be used to decide whether or not to take this medicine or any other medicine. Only a healthcare provider has the knowledge and training to decide which medicines are right for you. TelyRx does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a limited summary of general information about the medicine’s uses from the patient education materials and is not intended to be comprehensive. This limited summary does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not intended to provide medical advice, diagnosis or treatment and does not replace information you may receive from your healthcare provider. For a more detailed summary of information about the risks and benefits of using this medicine, please review the entire patient education information you receive with the medication.

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