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Brenzavvy® (bexagliflozin) is a prescription oral medication used to manage blood sugar levels in adults with type 2 diabetes. It belongs to a class of medications called SGLT2 inhibitors (sodium-glucose co-transporter 2 inhibitors), which help the kidneys remove excess sugar from the body by preventing glucose reabsorption in the renal tubules.
This mechanism leads to increased urinary glucose excretion, which lowers blood glucose (A1C) levels, works independently of insulin, and complements other diabetes medications.
Approved Use:
Approved for type 2 diabetes in adults, as an adjunct to diet and exercise. May also provide modest reductions in body weight and systolic blood pressure. Not approved for type 1 diabetes or diabetic ketoacidosis (DKA), or patients with severe kidney impairment or end-stage renal disease.
How to Use:
Typical dosage is to take 1 tablet once daily, with or without food
May be used alone or in combination with other antidiabetic medications, under the discretion of your healthcare provider
Important: As with all SGLT2 inhibitors, patients should be monitored for signs of urinary tract infections, volume depletion, and kidney function.
Brenzavvy® (bexagliflozin) may cause a range of side effects, both common and serious. Common side effects include increased urination, urinary tract infections (UTIs), and genital yeast infections, which may present as itching, redness, swelling, or discharge. More serious risks include diabetic ketoacidosis—a potentially life-threatening condition marked by nausea, vomiting, abdominal pain, and difficulty breathing—as well as dehydration, which can lead to dizziness or low blood pressure. Severe urinary tract infections, including kidney infections and urosepsis, have also been reported. Patients may experience low blood sugar (hypoglycemia), especially when used with insulin or insulin secretagogues, with symptoms such as shakiness, confusion, and rapid heartbeat. Rare but serious adverse effects include Fournier’s gangrene, a severe infection of the genital region, and an increased risk of lower limb amputations, particularly in individuals with a history of foot ulcers or poor circulation. Regular monitoring and prompt reporting of symptoms to a healthcare provider are essential while taking Brenzavvy®.
This information should not be used to decide whether or not to take this medicine or any other medicine. Only a healthcare provider has the knowledge and training to decide which medicines are right for you. TelyRx does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a limited summary of general information about the medicine’s uses from the patient education materials and is not intended to be comprehensive. This limited summary does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not intended to provide medical advice, diagnosis or treatment and does not replace information you may receive from your healthcare provider. For a more detailed summary of information about the risks and benefits of using this medicine, please review the entire patient education information you receive with the medication.
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Make sure you have created an account with TelyRx if you haven't already done so. Select the “I have a prescription” option when adding your request to your cart. If we don’t have the exact medication (dosage, quantity, formulation) matching your prescription, we recommend that you request a prescription through our platform to reduce any potential delay or denial. Provide your current pharmacy’s name and phone number, as well as your prescription number. Our customer service team will reach out for more information as needed.
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