Flea, Tick, & Heartworm Prevention
Simparica Trio pet
starting at $0.00

Simparica Trio is a once-monthly chewable tablet for dogs that provides comprehensive protection against internal and external parasites. It combines three active ingredients—sarolaner, moxidectin, and pyrantel—to protect against heartworm disease, five types of ticks, fleas, roundworms, and hookworms. This broad-spectrum medication simplifies parasite prevention by addressing multiple threats with a single dose.

  • Simparica Trio protects dogs against heartworms, fleas, ticks, roundworms, and hookworms.
  • It combines sarolaner, moxidectin, and pyrantel in a single monthly chewable tablet.
  • The chew starts killing fleas within hours and maintains effectiveness for a full month.
  • It offers broad-spectrum parasite control, reducing the need for multiple medications.
  • Simparica Trio is approved for dogs as young as 8 weeks and weighing at least 2.8 pounds.
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  • Simparica Trio Side Effects

    Simparica Trio side effects may include vomiting, diarrhea, lethargy, decreased appetite, and itching. While most dogs tolerate the medication well, some may experience gastrointestinal upset after administration. In rare cases, especially in dogs with a history of seizures or neurologic disorders, tremors, ataxia (loss of coordination), or seizures may occur. These effects are generally transient but warrant veterinary attention if observed.

  • Consumer Information Use and Disclaimer

    This information should not be used to decide whether or not to take this medicine or any other medicine. Only a healthcare provider has the knowledge and training to decide which medicines are right for you. TelyRx does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a limited summary of general information about the medicine’s uses from the patient education materials and is not intended to be comprehensive. This limited summary does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not intended to provide medical advice, diagnosis or treatment and does not replace information you may receive from your healthcare provider. For a more detailed summary of information about the risks and benefits of using this medicine, please review the entire patient education information you receive with the medication.

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