Xopenex HFA® inhaler (levalbuterol) is a prescription bronchodilator commonly prescribed for the treatment or prevention of bronchospasm in patients with reversible obstructive airway disease, such as asthma or chronic obstructive pulmonary disease (COPD). It may also be prescribed to help prevent exercise-induced bronchospasm when used shortly before physical activity.
Levalbuterol is the active (R)-enantiomer of albuterol, designed to provide effective airway relaxation with potentially fewer side effects such as jitteriness or rapid heartbeat in some patients. Xopenex works by relaxing the smooth muscles around the airways, making it easier to breathe.
How to Use
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Xopenex HFA is typically prescribed as 2 inhalations (90 mcg per actuation) every 4 to 6 hours as needed for bronchospasm.
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Some patients may need only 1 inhalation every 4 hours; dosing is individualized based on symptoms and provider direction.
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Shake the inhaler well before each use.
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Prime the inhaler before first use, or if it has not been used for more than 3 days, by releasing 4 sprays into the air away from the face.
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Inhale the medication deeply into the lungs and hold your breath for several seconds before exhaling.
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Do not exceed the prescribed number of inhalations per day, as overuse can increase the risk of side effects.
Important Notes and Warnings
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Common side effects may include headache, dizziness, nervousness, tremor, or rapid heartbeat.
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Serious risks include chest pain, irregular heart rhythm, or paradoxical bronchospasm (worsening of breathing immediately after inhalation). Discontinue use and seek medical attention if these occur.
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Patients with heart disease, high blood pressure, seizures, thyroid disorders, or diabetes should use this medication with caution.
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Xopenex HFA is a rescue inhaler; it should not be used as a replacement for long-term controller medications such as inhaled corticosteroids.
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Inform your provider about all other medications you are taking, including other inhalers, beta-blockers, and diuretics, as interactions are possible.
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Overuse may reduce the medication’s effectiveness and increase the likelihood of adverse effects.