Rybelsus® (semaglutide) is a prescription medication approved for the management of type 2 diabetes in adults. It belongs to a class of drugs called GLP-1 receptor agonists, which work by mimicking the incretin hormone GLP-1. This action increases insulin release after meals, decreases glucagon secretion, and slows stomach emptying, helping improve blood sugar control. Additionally, semaglutide can help reduce appetite and promote a feeling of fullness, which may contribute to weight loss.
While Rybelsus® is primarily prescribed for type 2 diabetes, its active ingredient, semaglutide, is also used off-label for weight loss in certain patients. Consistent use, alongside a healthy diet and exercise, not only improves blood sugar control but may also reduce the risk of diabetes-related complications such as kidney damage, nerve problems, vision loss, and cardiovascular events like heart attack or stroke.
Usage Instructions
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Take exactly as prescribed by your healthcare provider
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Swallow tablets whole with a small amount of water at least 30 minutes before eating, drinking, or taking other oral medications
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The typical starting dose is 3mg and adjusted in coordination with tolerability of side effects and effectiveness
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Maintain a balanced diet and regular exercise program while taking this medication
Warnings & Precautions
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Do not use if you have a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2)
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Use with caution if you have a history of pancreatitis, diabetic retinopathy, or kidney disease
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Possible side effects include nausea, vomiting, diarrhea, abdominal pain, or decreased appetite; these are often temporary and may improve with time
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Seek immediate medical attention for signs of pancreatitis such as severe abdominal pain that may radiate to the back
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Inform your healthcare provider of all medications you take, as some drugs may interact with semaglutide