Xopenex HFA® inhaler (levalbuterol) is a prescription bronchodilator commonly prescribed to treat or prevent bronchospasm in conditions such as asthma or chronic obstructive pulmonary disease (COPD). It is also often prescribed for patients with exercise-induced bronchospasm (EIB), a condition in which physical activity triggers shortness of breath, wheezing, or chest tightness.
Levalbuterol is the active (R)-enantiomer of albuterol and works by relaxing the smooth muscles in the airways, allowing them to open and making breathing easier. Compared to albuterol, some patients may tolerate levalbuterol better, with fewer side effects such as jitteriness or rapid heartbeat.
How to Use
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For exercise-induced bronchospasm, Xopenex HFA is often prescribed as 2 inhalations taken about 15 to 30 minutes before physical activity, as directed by your healthcare provider.
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For bronchospasm relief, the usual adult and adolescent dosing is 2 inhalations every 4 to 6 hours as needed.
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Shake the inhaler well before each use.
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Prime the inhaler before first use, or if it has not been used for more than 3 days, by spraying 4 test sprays into the air away from the face.
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Inhale the medication deeply and hold your breath for several seconds before exhaling.
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Do not exceed the prescribed maximum daily number of inhalations. Overuse can increase side effects and reduce effectiveness.
Important Notes and Warnings
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Xopenex HFA is considered a rescue inhaler — it provides quick relief but does not replace daily controller medications such as inhaled corticosteroids.
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Common side effects may include nervousness, headache, tremor, or a rapid heartbeat.
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Serious but less common side effects include chest pain, irregular heartbeat, or worsening breathing immediately after use (paradoxical bronchospasm). If these occur, stop using and seek medical care immediately.
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Patients with heart disease, high blood pressure, diabetes, seizure disorders, or thyroid disease should use with caution and under close supervision.
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Inform your healthcare provider of all other medications you are taking, particularly other inhalers, beta-blockers, or diuretics, as interactions may occur.
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