Promethazine is a prescription medication that functions as both an antiemetic and a first-generation antihistamine. It is used to prevent and treat motion sickness, as well as to control nausea and vomiting from various causes, including after surgery or during illness. In addition, promethazine is indicated for relief of allergic conditions such as seasonal allergies, allergic conjunctivitis, and uncomplicated skin reactions like hives.
By blocking histamine receptors in the body, promethazine helps reduce allergy symptoms such as sneezing, itching, watery eyes, and skin irritation. Its antiemetic properties work by affecting the brain’s vomiting center, making it effective for nausea prevention and relief.
Usage Instructions:
Take exactly as prescribed by your healthcare provider
May be taken with food, water, or milk to reduce stomach upset
For motion sickness, take the first dose 30–60 minutes before travel or as directed by your provider
Avoid alcohol while taking promethazine, as it can increase drowsiness
Warnings & Precautions:
May cause marked drowsiness; use caution when driving or operating machinery
Avoid alcohol and other central nervous system depressants while taking this medication
Use with caution in patients with glaucoma, breathing disorders, seizure disorders, or liver disease
May cause side effects such as dry mouth, blurred vision, constipation, or dizziness
Inform your healthcare provider if you are pregnant, breastfeeding, or taking other sedating medications
Promethazine side effects may include fatigue, blurred vision, dry mouth, nausea, vomiting, trouble sleeping, constipation, urinary retention, dizziness, drowsiness
This information should not be used to decide whether or not to take this medicine or any other medicine. Only a healthcare provider has the knowledge and training to decide which medicines are right for you. TelyRx does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a limited summary of general information about the medicine’s uses from the patient education materials and is not intended to be comprehensive. This limited summary does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not intended to provide medical advice, diagnosis or treatment and does not replace information you may receive from your healthcare provider. For a more detailed summary of information about the risks and benefits of using this medicine, please review the entire patient education information you receive with the medication.