Clindamycin and benzoyl peroxide topical gel is a combination acne medication used to treat mild to moderate inflammatory acne. Clindamycin is a topical antibiotic that works by inhibiting bacterial protein synthesis, helping to reduce the number of acne-causing bacteria and inflammation on the skin. Benzoyl peroxide is a keratolytic agent and antibacterial that penetrates pores to clear out dead skin cells and excess sebum while killing surface bacteria that contribute to acne formation.
The synergistic effect of these two active ingredients targets multiple causes of acne—bacterial growth, clogged pores, and inflammation—making it a first-line treatment option for inflammatory acne.
This medication is well tolerated by most individuals and typically starts to show results in 2 to 6 weeks of consistent use. Maximal benefit is often seen within 12 weeks. Continued use as prescribed can help maintain clearer skin.
How to Use:
Apply a thin layer to clean, dry skin once or twice daily or as directed
Avoid eyes, lips, and inside of the nose
Wash hands after application
Use sunscreen daily to prevent photosensitivity
Warnings:
May cause dryness, redness, or peeling, especially in the first few weeks
Avoid using other harsh topical products unless advised by a provider
Not for use in individuals with a history of antibiotic sensitivity without prior consultation
Discontinue if severe irritation or allergic reaction develops