How It Works
Bimatoprost mimics the effects of prostaglandins. In the eye, these compounds help regulate the flow of fluid within the eye (aqueous humor). When this fluid does not drain as it should, pressure can build and cause damage to the eye and vision.
Bimatoprost activates prostaglandin receptors in the eye to open drainage pathways. By increasing fluid outflow, the medication lowers intraocular pressure.
When used for eyelashes, bimatoprost increases the duration of the growth phase in lash hair follicles. This results in lashes that remain attached longer and grow to a greater length before naturally shedding.
The medication also increases the amount of a dark pigment called melanin in the treated area. This makes lashes appear darker and more prominent. However, this same process can lead to gradual changes in the color of the eyelid skin or the iris.
| Quick Facts | |
|---|---|
| Common Brands | Lumigan, Latisse, Durysta (implant) |
| Drug Class | Prostaglandin analog; prostaglandin agonist |
| Generic Status | Generic version of Lumigan |
| Availability | Prescription only |
Dosing
Bimatoprost is available in concentrations of 0.01% and 0.03%. The lower concentration is often used specifically for managing eye pressure, while the higher concentration is used for both eye pressure and eyelash growth. Standard guidelines suggest using the medication once daily, typically in the evening.
For eye pressure, one drop is placed directly into the affected eye(s).
For eyelash growth, the solution is applied to the skin of the upper eyelid margin at the base of the lashes using a sterile applicator. It is important to avoid applying the solution to the lower lash line to prevent unwanted hair growth.
If you use the medication for both eye pressure and lash growth, your provider will give you specific instructions on how to coordinate these applications safely.
Note: Dosing information below is educational only. Your prescribing physician will determine your specific dose based on your individual health needs. Always follow your healthcare provider’s instructions for exact dosing.
Uses
FDA-Approved Uses
Bimatoprost is FDA-approved for the reduction of pressure inside the eye (elevated intraocular pressure) in patients with open-angle glaucoma or ocular hypertension. It is also FDA-approved for the treatment of thin or insufficient eyelashes (eyelash hypotrichosis).
Off-Label Uses
You may see bimatoprost eye drops prescribed for uses that are not “FDA-approved.” This is a common and legal practice called “off-label” prescribing, where a doctor uses their clinical judgment to prescribe a drug for a different (but well-researched) purpose. Providers may prescribe bimatoprost eye drops off-label for the following conditions:
- Eyebrow growth: While approved for lashes, some providers prescribe the solution to help thicken and darken thinning eyebrows.
- Hormone therapy-induced hair loss: Individuals experiencing lash thinning due to certain medical treatments.
- Alternative pressure management: The medication may be used off-label in concentrations or frequencies different from the standard label for resistant cases of glaucoma.
Side Effects
Bimatoprost side effects include changes to the eye and the surrounding skin. Many of these effects are cosmetic and may be reversible, but some changes can be permanent. It is important to monitor your eyes closely and stay in contact with your provider if you notice any significant changes in your vision or eye appearance.
Common Side Effects
- Eye redness
- Itchy or irritated eyes
- Darkening of the eyelid skin
- Darkening of the eyelashes
- Dry eye sensation
- Increased eyelash growth
Serious Side Effects
Serious side effects are rare, but it’s important to know what to look for if they do occur. Call your doctor if you experience:
- Iris color change: Bimatoprost may gradually increase the amount of brown pigment in the iris (the colored part of the eye), causing the eye color to become darker. This change may be permanent, even after the medication is stopped.
- Macular edema: Retinal swelling caused by too much fluid can result in blurry or wavy vision or make colors look dull.
- Bacterial keratitis: A serious infection of the cornea can happen if the dropper tip becomes contaminated.
- Severe allergic reaction: Symptoms may include hives, swelling of the face or throat, and difficulty breathing.
- Vision loss or eye pain: Any sudden decrease in vision or significant pain inside the eye requires immediate medical evaluation.
Call your doctor immediately if you experience any concerning or prolonged symptoms.
Pharmacist Tips
Remove Contact Lenses
The preservative in these drops can be absorbed by soft contact lenses, damaging them. Removing lenses before use and waiting 15 minutes before putting them back in prevents lens damage and discoloration.
Practice Dropper Hygiene
Avoid letting the tip of the bottle touch your eye, fingers, or any other surface. Contaminating the tip can lead to serious bacterial infections that may threaten your eyesight.
Apply In The Evening
Using bimatoprost eye drops at night is standard practice because the medication is often more effective at controlling eye pressure during sleep. Evening use also allows any initial redness to subside by morning.
Use Single-Use Applicators
When using the eyelash medication, always use a fresh, sterile applicator for each eye. Reusing applicators or washing them increases the risk of introducing bacteria to the eyelid.
Wipe Away Excess
If the liquid runs off the eyelid or out of the eye, wipe it away immediately with an absorbent cloth. This prevents the medication from causing unwanted hair growth on the cheeks or face.
Be Patient With Results
Changes in eyelash length and thickness typically take 8 to 16 weeks to become noticeable.
Monitor Eye Color
Keep a close watch on the color of your irises, especially if you have hazel or green eyes. Changes in brown pigment are usually permanent, even after the medication is stopped.
Drug Interactions
Bimatoprost eye drops primarily work locally, but they can still interact with other substances or treatments.
- Other prostaglandin analogs: Using bimatoprost eye drops with other drops, such as latanoprost, can reduce the pressure-lowering effect.
- Bimatoprost implants: If you have recently received a bimatoprost implant, using additional drops may cause excessively low intraocular pressure.
- Corticosteroid eye drops: Using steroid drops alongside bimatoprost can sometimes complicate the management of eye pressure and requires close monitoring.
- Soft contact lenses: The chemicals in the bimatoprost solution can react with the materials in soft lenses, leading to irritation or lens degradation if the solution is not removed.
Always give your doctor and pharmacist a complete list of all your medications, vitamins, and supplements to check for potential interactions.
FAQs
What is the difference between using Latisse for my eyelashes and Lumigan for my eye pressure?
The primary difference lies in the concentration and the method of application. Lumigan is typically used directly in the eye to lower pressure. Latisse is FDA-approved for eyelash growth and is carefully applied to the upper lash line at the base of the eyelashes using a sterile applicator.
If I stop using this medication, will my new growth eyelashes fall out and go back to normal?
Yes, the effects of bimatoprost on eyelashes are not permanent. If you discontinue treatment, your eyelashes will gradually return to their original appearance and thickness over several weeks to months.
Why did the pharmacist tell me to only apply this to my upper lash line?
Applying the medication to the lower lash line significantly increases the risk of the solution spreading to other parts of the face. This can cause unwanted hair growth on the skin below the eye or darken the skin in that area.
Can I put my contact lenses back in immediately after using these drops?
Generally, no. Follow your provider’s instructions. Guidelines usually recommend waiting at least 15 minutes after using the drops before reinserting soft contact lenses. This allows the preservative in the medication to clear from the eye surface, preventing damage to the lenses.
Is it normal to wake up with my eyes feeling extremely red or irritated after using bimatoprost before bed?
Mild redness and itching are common side effects of bimatoprost. While these effects are often temporary, you should report persistent or severe redness to your provider to ensure it is not a sign of inflammation or infection.
Can I use lubricating artificial tears if this medication dries my eyes out?
Artificial tears are often used to manage the dry eye sensation associated with this treatment. Standard guidelines suggest waiting at least five minutes between using bimatoprost and any other eye drop to ensure proper absorption. That said, ask your provider for specific instructions.
Why is the Latisse applicator brush single-use only, and what happens if I wash and reuse it?
Single-use applicators help prevent eye infections. Washing a brush does not guarantee it is sterile, and reusing it can introduce bacteria to the delicate eyelid area.
Is it safe to get professional eyelash extensions or wear mascara while actively using this treatment?
You can generally continue using mascara or wearing eyelash extensions, but the bimatoprost solution should be applied to a clean, makeup-free eyelid. After application, ensure the solution has completely dried before applying any other products to the area.
Can I safely use this drop if I am currently pregnant or breastfeeding?
Researchers have not well studied the effects of bimatoprost on unborn babies, so risk cannot be ruled out. Doctors also recommend caution for those who are breastfeeding.
Comparable Medications
Bimatoprost vs Latisse, Latanoprost, or Timolol?
Latisse®
From $199.99
Latisse is the brand-name version of bimatoprost specifically approved for eyelash growth. Latisse is packaged with sterile applicators for eyelid use.
Latanoprost
From $29.99
Latanoprost is another prostaglandin analog used to treat high eye pressure. It is often a first-choice treatment because it may cause less eye redness than bimatoprost. However, some studies suggest that bimatoprost may be slightly more effective at reaching target pressure levels. Unlike bimatoprost, latanoprost is not approved for eyelash growth.
Timolol Eye Drops
From $27.99
Timolol belongs to a different class of drugs called beta-blockers. It lowers eye pressure by decreasing the production of aqueous humor rather than increasing drainage within the eye. Timolol does not cause eyelash growth or skin darkening, but it may affect heart rate and breathing.
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Important: Information on this page is for educational purposes only. Prescribing decisions are made by independent, licensed providers. TelyRx operates technology-enabled pharmacies and a telehealth platform that connects patients with licensed providers. Prescriptions, when provider-approved and issued, are filled and shipped by TelyRx-affiliated pharmacies. We do not employ physicians or make prescribing decisions. Learn more about our editorial standards here.