Colesevelam is a bile acid sequestrant used to lower LDL (bad) cholesterol in patients with high cholesterol and to improve blood sugar control in adults with type 2 diabetes. It works by binding bile acids in the intestine, which helps remove cholesterol from the body. Colesevelam is typically taken with meals and is not absorbed into the bloodstream, making it a good option for patients who cannot tolerate systemic cholesterol-lowering medications.
- Colesevelam is a bile acid sequestrant used to lower LDL cholesterol levels.
- It is also FDA-approved to improve glycemic control in adults with type 2 diabetes.
- The medication works by binding bile acids in the intestine, preventing their reabsorption.
- This process forces the liver to use more cholesterol to make bile acids, reducing blood cholesterol.
- Colesevelam is not absorbed into the bloodstream, which reduces the risk of systemic side effects.
- It is often used as an add-on therapy when statins or other medications are not enough.
- Colesevelam is available in tablet and oral suspension forms.
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Colesevelam Side Effects
Colesevelam side effects may include the following:
The most common side effect of colesevelam is constipation, which may be accompanied by bloating, gas, or abdominal discomfort. Some people may also experience indigestion, nausea, or a feeling of fullness. Although rare, increased triglyceride levels can occur, especially in individuals who already have elevated triglycerides. Other uncommon side effects include headache, muscle aches, and fatigue. Because colesevelam can interfere with the absorption of other medications and fat-soluble vitamins (A, D, E, and K), long-term use may occasionally lead to deficiencies if not managed properly. Serious allergic reactions are very rare but can include rash, itching, swelling, or difficulty breathing. Anyone experiencing persistent or severe symptoms should consult their healthcare provider.
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Consumer Information Use and Disclaimer
This information should not be used to decide whether or not to take this medicine or any other medicine. Only a healthcare provider has the knowledge and training to decide which medicines are right for you. TelyRx does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a limited summary of general information about the medicine’s uses from the patient education materials and is not intended to be comprehensive. This limited summary does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not intended to provide medical advice, diagnosis or treatment and does not replace information you may receive from your healthcare provider. For a more detailed summary of information about the risks and benefits of using this medicine, please review the entire patient education information you receive with the medication.
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