Progesterone is a naturally occurring female hormone used to help prevent endometrial hyperplasia, a precancerous thickening of the uterine lining, in individuals receiving estrogen therapy after menopause. Estrogen alone can stimulate the uterine lining and increase the risk of abnormal changes. By balancing estrogen’s effects, progesterone helps protect the endometrium, reducing the risk of heavy bleeding, postmenopausal spotting, and related complications such as anemia.
Progesterone capsules are generally prescribed for postmenopausal individuals with an intact uterus who are receiving systemic estrogen therapy. Treatment may be given on a cyclical schedule or as continuous daily therapy, depending on patient needs and provider recommendations.
Usage Instructions
• Take exactly as prescribed by your healthcare provider
• May be administered cyclically or continuously
• Swallow capsules whole with a full glass of water, with or without food
• Take at the same time each day to maintain consistent hormone levels
• Follow your provider’s instructions on timing in relation to estrogen therapy
Warnings & Precautions
• For use only in individuals with an intact uterus who are receiving estrogen therapy
• Not intended for use in pregnancy. Inform your provider if you may be pregnant or breastfeeding
• May cause dizziness, headaches, bloating, or breast tenderness
• Use with caution if you have a history of blood clots, liver disease, certain cancers, or cardiovascular disease
• Report any unusual vaginal bleeding promptly, as it may indicate a more serious condition
• Hormone therapy should be used for the shortest duration necessary to meet treatment goals