Yuvezzi is a prescription eye drop used once daily to treat presbyopia, the gradual, age-related loss of near vision that makes reading, texting, or other close-up tasks more difficult. It combines two active ingredients, carbachol and brimonidine tartrate, which work together to shrink the pupil and hold it in that smaller state, creating a pinhole effect that sharpens close-up focus. By improving near vision without surgery, Yuvezzi gives adults with presbyopia another way to manage everyday close-up tasks, whether used alone or alongside glasses or contact lenses for distance vision.
Yuvezzi (carbachol and brimonidine tartrate ophthalmic solution, 2.75%/0.1%) is a fixed-dose combination eye drop approved for the treatment of presbyopia in adults. Presbyopia occurs as the lens of the eye becomes less flexible with age, typically starting around 45, and affects the large majority of adults over that age. Yuvezzi works through two complementary mechanisms: carbachol, a cholinergic agonist, constricts the iris sphincter and ciliary body to narrow the pupil, while brimonidine, an alpha-adrenergic agonist, limits the pupil from widening again and extends how long the effect lasts. Together, these actions create a small-aperture, or pinhole, effect that increases depth of focus and sharpens near visual acuity, generally within about 30 minutes and lasting up to 8 to 10 hours per dose.
Yuvezzi is administered as one drop in each eye, once daily, using a preservative-free single-dose vial that should be discarded after use; one vial contains enough solution for both eyes. Patients who wear contact lenses should remove them before dosing and wait at least 10 minutes before reinserting them, and if other topical eye medications are used, they should be spaced at least 5 minutes apart from Yuvezzi. Because it does not require surgery, Yuvezzi can serve as a first-line or adjunctive option for patients looking to reduce dependence on reading glasses, and it can be used together with corrective lenses worn for distance vision. This medication should be used with caution in patients with a history of iritis, depression, low blood pressure, or circulatory conditions, since the medication's effects on the pupil and blood vessels can interact with these conditions. Counseling should emphasize proper instillation technique, the importance of not touching the vial tip to the eye or eyelid, and awareness that vision may be temporarily blurred or dimmed, particularly in low light.
The most commonly reported side effects of Yuvezzi include eye pain or irritation at the time the drops are instilled, headache, and temporary visual disturbances such as blurry, dim, or dark vision, most of which are mild and resolve on their own. Patients experiencing blurred vision should avoid driving, operating machinery, or performing other hazardous tasks, and should use extra caution with night driving or activities in low light. More serious but rare concerns include retinal tear or detachment, which can occur with pupil-constricting medications like this one, so patients should seek medical attention right away if they notice sudden flashes of light, new floaters, or vision loss. Yuvezzi should not be used by anyone with known hypersensitivity to its ingredients or with active iritis, and it should be used cautiously by people with a history of low blood pressure, poor circulation, Raynaud's phenomenon, dizziness upon standing, or depression, since brimonidine can lower blood pressure and may interact with blood pressure medications or heart-related drugs. Patients should also watch for signs of an allergic reaction, such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat, and seek emergency care if these occur, and should be careful not to let the vial tip touch the eye or any surface to avoid injury or contamination.
This information should not be used to decide whether or not to take this medicine or any other medicine. Only a healthcare provider has the knowledge and training to decide which medicines are right for you. TelyRx does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a limited summary of general information about the medicine’s uses from the patient education materials and is not intended to be comprehensive. This limited summary does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not intended to provide medical advice, diagnosis or treatment and does not replace information you may receive from your healthcare provider. For a more detailed summary of information about the risks and benefits of using this medicine, please review the entire patient education information you receive with the medication.
Testimonials
What patients are saying
★★★★★
4.7 out of 5
4,099 verified reviews on Trustpilot
★★★★★5.0 (128 reviews)
This is the best thing to happen since…
Thank you Telrx for creating this company. It's so hard to get doctor's appointments! For common ailments, we usually know what we need before we go to the doctor's office...this saves so much time, money and headache! Thank You!!
★★★★★5.0 (128 reviews)
Great Service
Great service. No more waiting for an appointment for the medication I've been taking for quite a while, with much success. Received doctor approval and the medication was shipped to me without any delays.
★★★★★5.0 (128 reviews)
This is the first time using an online prescription pharmacy
I was hesitant, but everything about the experience was very positive. From requesting the medication to receiving it was quick and easy. From time of order to receipt was only 2 days. Very happy and will not hesitate to use in the future.
★★★★★5.0 (128 reviews)
AMAZING ease to purchase
Where was this place all my life? No costly doctor's appts where you have to get a referral through Kaiser then drive then wait. Got an eczema cream for my daughter in 5 mins. Will be back
★★★★★5.0 (128 reviews)
I've been taking Blood Pressure meds…
I've been taking Blood Pressure meds for several years. Always going through the hassle of doctor's office and waiting rooms. TelyRx has made office visit's obsolete with its exceptional services.
Answers to common questions about treatment, pricing, and how this all works.
Why should I trust TelyRx?
Every order is reviewed virtually by a healthcare provider licensed in your state. Our licensed pharmacies dispense only FDA-approved medications and our platform provides HIPAA-level privacy protection. With TelyRx, you get real healthcare with real oversight.
Is insurance required?
No. TelyRx works outside of insurance entirely. The price you see is the price you pay. No prior authorizations, no claim denials, no waiting on approvals.
What will my medication cost?
Search any medication on our site and see your price instantly — no account required. The provider review is a flat $22 fee per order, whether you need one medication or multiple. Most people pay a fraction of what they’d pay at a typical pharmacy.
Do I need to have a prescription?
Not to get started. Complete a short health attestation, and a licensed provider will review your request entirely online. Already have a prescription? You can transfer it to TelyRx directly.
How do I transfer my existing prescription to the TelyRx platform?
Make sure you have created an account with TelyRx if you haven't already done so. Select the “I have a prescription” option when adding your request to your cart. If we don’t have the exact medication (dosage, quantity, formulation) matching your prescription, we recommend that you request a prescription through our platform to reduce any potential delay or denial. Provide your current pharmacy’s name and phone number, as well as your prescription number. Our customer service team will reach out for more information as needed.
If your prescription details differ from the order you submitted, such as if the dosage differs, your order will be cancelled and you will not be charged.
If we do not have your exact match in dosage, quantity, or formulation, we recommend selecting the “I need a prescription” option to avoid potential fulfillment delays. Your request will be reviewed by an independent, licensed provider.
Why does my medicine look different than the product photo?
Medication appearance can vary depending on the manufacturer. No matter which company creates it, the drug you receive will always be FDA-approved and bioequivalent. This means it contains the same active ingredient(s), at the same dosage, for the same intended use. The medicine you receive is just as safe and effective, even if it doesn't look exactly like the photo.
We work with a network of trusted American wholesalers and manufacturers to keep your medications high-quality, FDA-approved, and reliably in stock. From time to time, we may switch manufacturers to ensure you never run out of the medication you depend on.
In the rare case that a bioequivalent version isn't available, we'll cancel your order and refund you the cost — because your safety always comes first.