Women's Health
Estradiol Patches (Twice Weekly)
Generic For Alora®; Minivelle®; Vivelle-Dot®
starting at $89.99

Estradiol patches are a form of hormone replacement therapy (HRT) used to treat symptoms of menopause such as hot flashes, night sweats, and vaginal dryness. They deliver a steady dose of estradiol, a form of estrogen, through the skin and into the bloodstream. This helps to restore estrogen levels that naturally decline during menopause. Estradiol patches may also be used to prevent bone loss (osteoporosis) in postmenopausal women. The patch is typically applied to the lower abdomen or buttocks and replaced according to a prescribed schedule.

  • Estradiol patches provide a continuous release of estrogen through the skin to help relieve menopausal symptoms.
  • They are commonly prescribed to reduce hot flashes, night sweats, and vaginal dryness associated with menopause.
  • The patches may also be used to prevent postmenopausal osteoporosis when non-estrogen options are not suitable.
  • Estradiol is a bioidentical form of estrogen, meaning it is chemically identical to the hormone produced by the body.
  • Transdermal delivery avoids first-pass metabolism in the liver, which may reduce the risk of certain side effects compared to oral estrogen.
  • Estradiol patches are typically applied to clean, dry skin on the lower abdomen or buttocks.
  • The patch should not be placed on or near the breasts and should be rotated to different sites with each application.
HSA/FSA Eligible

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  • Estradiol Patches (Twice Weekly) Side Effects

    Estradiol patches may cause side effects such as skin irritation or redness at the application site, breast tenderness, headache, nausea, bloating, and mood changes. Some individuals may also experience breakthrough bleeding, fluid retention, mild weight changes, decreased or increased libido, and discomfort with contact lenses. More serious but less common risks include blood clots, stroke, heart attack, and certain types of cancer, including breast and endometrial cancer—particularly with long-term use or when used without a progestin in women with an intact uterus. Symptoms that warrant immediate medical attention include chest pain, sudden severe headache, vision changes, leg swelling or pain, shortness of breath, or unusual vaginal bleeding. The likelihood of experiencing side effects can vary based on age, medical history, and lifestyle factors such as smoking. To minimize risk, estradiol patches should be used at the lowest effective dose for the shortest duration necessary, under the guidance of a healthcare provider.

  • Consumer Information Use and Disclaimer

    This information should not be used to decide whether or not to take this medicine or any other medicine. Only a healthcare provider has the knowledge and training to decide which medicines are right for you. TelyRx does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a limited summary of general information about the medicine’s uses from the patient education materials and is not intended to be comprehensive. This limited summary does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not intended to provide medical advice, diagnosis or treatment and does not replace information you may receive from your healthcare provider. For a more detailed summary of information about the risks and benefits of using this medicine, please review the entire patient education information you receive with the medication.

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