{"id":9450,"date":"2026-06-29T11:31:27","date_gmt":"2026-06-29T11:31:27","guid":{"rendered":"https:\/\/telyrx.com\/blog\/?p=9450"},"modified":"2026-06-29T15:49:08","modified_gmt":"2026-06-29T15:49:08","slug":"what-is-amlodipine-valsartan-hctz-tablets","status":"publish","type":"post","link":"https:\/\/telyrx.com\/blog\/medications\/what-is-amlodipine-valsartan-hctz-tablets\/","title":{"rendered":"What Is Amlodipine-Valsartan-HCTZ?"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\" id=\"h-how-it-works\">How It Works<\/h2>\n\n\n\n<p>Amlodipine-valsartan-HCTZ contains three active ingredients that work together to relax blood vessels and reduce fluid volume in the body.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Amlodipine: <\/strong>This calcium channel blocker (CCB) works by relaxing the blood vessels. This allows blood to flow through them more easily, which reduces blood pressure.<\/li>\n\n\n\n<li><strong>Valsartan:<\/strong> This angiotensin II receptor blocker (ARB) works by blocking the effects of angiotensin II, a hormone that constricts blood vessels and raises blood pressure. By blocking this hormone, valsartan helps the blood vessels stay relaxed and reduces the release of aldosterone, a hormone that causes the body to retain sodium and water.\u00a0<\/li>\n\n\n\n<li><strong>Hydrochlorothiazide (HCTZ):<\/strong> This thiazide diuretic, or \u201cwater pill,\u201d works in the kidneys to remove excess salt and water from the body through urine. Reducing the overall amount of fluid flowing through the blood vessels helps lower blood pressure.<\/li>\n<\/ul>\n\n\n\n<div class=\"quick-facts-card\">\n  <table class=\"quick-facts-table\">\n    <colgroup>\n      <col\/>\n      <col\/>\n    <\/colgroup>\n\n    <thead>\n      <tr>\n        <th colspan=\"2\">Quick Facts<\/th>\n      <\/tr>\n    <\/thead>\n\n    <tbody>\n      <tr>\n        <td><strong>Common Brands<\/strong><\/td>\n        <td>Exforge HCT<\/td>\n      <\/tr>\n\n      <tr>\n         <td><strong>Drug Class<\/strong><\/td>\n        <td>Calcium channel blocker (CCB), angiotensin II receptor blocker (ARB), thiazide diuretic<\/td>\n      <\/tr>\n\n      <tr>\n        <td><strong>Generic Status<\/strong><\/td>\n        <td>Generic is available<\/td>\n      <\/tr>\n\n      <tr>\n         <td><strong>Availability<\/strong><\/td>\n        <td>Prescription only<\/td>\n    <\/tbody>\n  <\/table>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-dosing\">Dosing<\/h2>\n\n\n\n<p>The recommended dose of amlodipine-valsartan-HCTZ is one tablet taken by mouth once daily. The medication comes in five dosage strengths of amlodipine\/valsartan\/HCTZ:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>5 mg\/160 mg\/12.5 mg<\/li>\n\n\n\n<li>10 mg\/160 mg\/12.5 mg<\/li>\n\n\n\n<li>5 mg\/160 mg\/25 mg<\/li>\n\n\n\n<li>10 mg\/160 mg\/25 mg<\/li>\n\n\n\n<li>10 mg\/320 mg\/25 mg<\/li>\n<\/ul>\n\n\n\n<p>The typical starting dose is 5 mg of amlodipine, 160 mg of valsartan, and 12.5 mg of HCTZ daily. Exforge HCT is not typically used as an initial treatment for high blood pressure and is generally reserved for people who require at least two antihypertensive medications to achieve adequate blood pressure control. Depending on how well the medication controls blood pressure and whether any side effects occur, a prescriber may adjust the dosage.&nbsp;<\/p>\n\n\n\n<p>The maximum recommended daily dose is 10 mg of amlodipine, 320 mg of valsartan, and 25 mg of HCTZ.<\/p>\n\n\n\n<p><em><strong>Note:<\/strong> Dosing information below is educational only. Your prescribing physician will determine your specific dose based on your individual health needs. Always follow your healthcare provider\u2019s instructions for exact dosing.<\/em><\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-uses\">Uses<\/h2>\n\n\n\n<p><strong>FDA-Approved Uses<\/strong><\/p>\n\n\n\n<p>Amlodipine-valsartan-HCTZ is FDA-approved to treat high blood pressure (hypertension).<\/p>\n\n\n\n<p><strong>Off-Label Uses<\/strong><\/p>\n\n\n\n<p>You may see amlodipine-valsartan-HCTZ prescribed for uses that are not \u201cFDA-approved.\u201d This is a very common and legal practice called \u201coff-label\u201d prescribing, where a doctor uses their clinical judgment to prescribe a drug for a different (but well-researched) purpose.<\/p>\n\n\n\n<p>There are currently no common off-label uses for amlodipine-valsartan-HCTZ.<\/p>\n\n\n<div class=\"telyrx-email-cta telyrx-email-cta--banner alignfull wp-block-telyrx-email-signup\">\n\t\t<h2 class=\"telyrx-email-cta__heading\" data-toc-hidden=\"true\">Get Savings Updates<\/h2>\n\t<p class=\"telyrx-email-cta__description\">Join our mailing list for exclusive deals and more.<\/p>\n\t\t\t<form\n\t\t\tid=\"telyrx-email-form-1\"\n\t\t\tclass=\"telyrx-email-cta__form\"\n\t\t\tdata-portal-id=\"46401311\"\n\t\t\tdata-form-id=\"14e1d7d5-6b17-4228-b42e-c06d1a6c240b\"\n\t\t\tdata-i18n=\"{&quot;subscribe&quot;:&quot;Subscribe&quot;,&quot;success&quot;:&quot;Thanks! You&#039;re subscribed.&quot;,&quot;error&quot;:&quot;Something went wrong. Please try again.&quot;}\"\n\t\t>\n\t\t\t<div class=\"telyrx-email-cta__pill\">\n\t\t\t\t<input\n\t\t\t\t\ttype=\"email\"\n\t\t\t\t\tname=\"email\"\n\t\t\t\t\tclass=\"telyrx-email-cta__input\"\n\t\t\t\t\tplaceholder=\"Enter your email\"\n\t\t\t\t\trequired\n\t\t\t\t\tautocomplete=\"email\"\n\t\t\t\t\/>\n\t\t\t\t<button type=\"submit\" class=\"telyrx-email-cta__button\">\n\t\t\t\t\tSubscribe\t\t\t\t<\/button>\n\t\t\t<\/div>\n\t\t\t<p class=\"telyrx-email-cta__status\" aria-live=\"polite\"><\/p>\n\t\t<\/form>\n\t\t<noscript>\n\t\t\t<p class=\"telyrx-email-cta__noscript\">Please enable JavaScript to use the signup form.<\/p>\n\t\t<\/noscript>\n\t<\/div>\n\n\n\n<section class=\"telyrx-side-effects\" data-toc-title=\"Side Effects\">\n\t<h2 class=\"telyrx-side-effects__heading\">Side Effects<\/h2>\n\t<hr class=\"telyrx-side-effects__separator\">\n\t<div class=\"telyrx-side-effects__content\">\n\t\t\n\n<p>Like all medications, amlodipine-valsartan-HCTZ can cause side effects. Some common side effects may improve over time as your body adjusts to the medication. Other side effects may be serious and require medical attention.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-common-side-effects\">Common Side Effects<\/h3>\n\n\n\n<div class=\"telyrx-side-effects-chip telyrx-side-effects-chip--common\">\n\t\n\n<ul class=\"wp-block-list\">\n<li>Dizziness<\/li>\n\n\n\n<li>Headache<\/li>\n\n\n\n<li>Swelling in the hands, arms, feet, ankles, or legs<\/li>\n\n\n\n<li>Increased urination<\/li>\n\n\n\n<li>Fatigue<\/li>\n\n\n\n<li>Upset stomach<\/li>\n\n\n\n<li>Muscle spasms<\/li>\n\n\n\n<li>Back pain<\/li>\n\n\n\n<li>Nausea<\/li>\n\n\n\n<li>Common cold symptoms<\/li>\n<\/ul>\n\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-serious-side-effects\">Serious Side Effects<\/h3>\n\n\n\n<div class=\"telyrx-side-effects-chip telyrx-side-effects-chip--serious\">\n\t\n\n<p>Serious side effects are rare, but it&#8217;s important to know what to look for if they do occur. Stop using amlodipine-valsartan-HCTZ and call your doctor immediately if you experience:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Severe allergic reactions:<\/strong> Symptoms include swelling of the face, lips, tongue, or throat (angioedema); difficulty breathing or swallowing; racing heart; severe rash or itching; and\/or fever.\u00a0<\/li>\n\n\n\n<li><strong>Low blood pressure (hypotension):<\/strong> Amlodipine-valsartan-HCTZ may cause blood pressure to drop too low. The risk may be higher for people who are dehydrated or taking diuretics. Symptoms include dizziness, lightheadedness, fainting, confusion, or feeling weak or tired.\u00a0<\/li>\n\n\n\n<li><strong>Kidney damage:<\/strong> Symptoms may include a reduced need to urinate, fatigue or weakness, shortness of breath, confusion, nausea, seizures, and swelling in the feet, ankles, or legs.<\/li>\n\n\n\n<li><strong>Changes in electrolyte levels:<\/strong> Amlodipine-valsartan-HCTZ can alter potassium, sodium, calcium, and magnesium levels. Symptoms of an electrolyte imbalance include muscle cramps or twitching, weakness or tiredness, restlessness, nausea, constipation, vomiting, dizziness, difficulty breathing, and confusion.<\/li>\n\n\n\n<li><strong>Heart attack or chest pain:<\/strong> Amlodipine-valsartan-HCTZ may cause a heart attack or worsening chest pain, particularly when starting the medication or increasing your dose. The risk may be higher in people who have severe obstructive coronary artery disease. Symptoms include severe chest pain or pressure; discomfort spreading to the arm, shoulder, back, neck, or jaw; cold sweats; unusual tiredness; heartburn; and sudden dizziness or lightheadedness.<\/li>\n\n\n\n<li><strong>Vision problems:<\/strong> Amlodipine-valsartan-HCTZ can cause short-sightedness or narrow-angle glaucoma. Symptoms include eye pain or redness, trouble seeing faraway objects, seeing colorful halos around lights, vision loss, and severe headache or vomiting.<\/li>\n\n\n\n<li><strong>Gout flares:<\/strong> This medication can raise uric acid levels, which can cause or worsen gout. The risk may be higher in people with kidney problems or previous gout attacks. Symptoms include joint pain, redness, or swelling, often in the big toe.<\/li>\n\n\n\n<li><strong>Liver problems:<\/strong> Symptoms include jaundice (yellowing of the skin or eyes), stomach pain, dark urine, and fatigue.<\/li>\n\n\n\n<li><strong>Lupus: <\/strong>Amlodipine-valsartan-HCTZ may cause flare-ups of lupus or rarely, trigger lupus-like symptoms. Symptoms include tiredness, joint pain, and a rash on the cheeks and nose.<\/li>\n<\/ul>\n\n<\/div>\n\n\n\n<p class=\"has-muted-color has-text-color\" style=\"font-size:0.875rem\"><em>Call your doctor immediately if you experience any concerning or prolonged symptoms.<\/em><\/p>\n\n\t<\/div>\n<\/section>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-pharmacist-tips\">Pharmacist Tips<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-take-your-dose-consistently\">Take Your Dose Consistently<\/h3>\n\n\n\n<p>You can take amlodipine-valsartan-HCTZ at any time of day. The important thing is to choose a time that works for you and take it consistently to maintain steady levels of the drug in your system.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-take-your-dose-with-or-without-food\">Take Your Dose With Or Without Food<\/h3>\n\n\n\n<p>If it upsets your stomach, taking your dose with food may offer relief.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-manage-dizziness\">Manage Dizziness<\/h3>\n\n\n\n<p>Because this medication lowers blood pressure, it can cause you to feel dizzy when changing position from sitting or lying down to standing. Get up slowly and hold onto something for support.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-use-sun-protection\">Use Sun Protection<\/h3>\n\n\n\n<p>The hydrochlorothiazide component of the medication can make your skin more sensitive to sunlight, increasing the risk of sunburn. It\u2019s recommended to apply sunscreen and wear protective clothing when outdoors.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-monitor-blood-pressure-at-home\">Monitor Blood Pressure At Home<\/h3>\n\n\n\n<p>Healthcare providers often recommend tracking your blood pressure at home, logging the readings, and sharing them during follow-up visits to ensure the medication is working well for you.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-stay-hydrated\">Stay Hydrated<\/h3>\n\n\n\n<p>Dehydration can increase the risk of low blood pressure and kidney problems. Drink fluids throughout the day, especially if you experience excessive sweating, diarrhea, or vomiting.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-take-your-dose-as-prescribed\">Take Your Dose As Prescribed<\/h3>\n\n\n\n<p>Do not lower your dose or stop taking the medication without consulting your prescriber, as this can cause a dangerous spike in blood pressure.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-avoid-potassium-containing-supplements-medications-and-foods\">Avoid Potassium-Containing Supplements, Medications, And Foods<\/h3>\n\n\n\n<p>Amlodipine-valsartan-HCTZ can affect your potassium levels. Review any potassium-containing supplements or medications with your doctor. Ask if you should limit potassium in your diet.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-adopt-a-healthy-diet\">Adopt A Healthy Diet<\/h3>\n\n\n\n<p>It\u2019s often recommended to follow a low-salt, low-fat diet when taking the medication. Ask your doctor which foods you should eat to lower your blood pressure.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-limit-or-avoid-alcohol\">Limit Or Avoid Alcohol<\/h3>\n\n\n\n<p>Frequent or heavy drinking can raise blood pressure and worsen side effects like dizziness or lightheadedness.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-space-certain-medications-apart\">Space Certain Medications Apart<\/h3>\n\n\n\n<p>If you take bile acid sequestrants like cholestyramine (Prevalite), take your dose at least 4 hours before or 4 to 6 hours after your dose of amlodipine-valsartan-HCTZ.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-store-at-room-temperature\">Store At Room Temperature<\/h3>\n\n\n\n<p>Amlodipine-valsartan-HCTZ should be stored at 68\u00b0F to 77\u00b0F (20\u00b0C to 25\u00b0C) in a cool, dry place away from light.\u00a0<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-tell-your-provider-if-you-re-pregnant-or-breastfeeding\">Tell Your Provider If You\u2019re Pregnant Or Breastfeeding<\/h3>\n\n\n\n<p>Amlodipine-valsartan-HCTZ can harm an unborn baby. Some components of this medication are known or expected to pass into breast milk. Stop taking the medication if you become pregnant and tell your healthcare provider so that they can recommend a safe alternative.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-try-to-avoid-missing-a-dose\">Try To Avoid Missing A Dose<\/h3>\n\n\n\n<p>If you miss a dose of amlodipine-valsartan-HCTZ, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and take your next dose as usual. Do not take double or extra doses to make up for a missed one.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-drug-interactions\">Drug Interactions<\/h2>\n\n\n\n<p>Certain medications and substances can interact with amlodipine-valsartan-HCTZ, potentially altering how it works or increasing the risk of side effects. For example:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Nonsteroidal anti-inflammatory drugs (NSAIDs):<\/strong> Medications like ibuprofen and naproxen can interact with amlodipine-valsartan-HCTZ. NSAIDs may reduce the blood pressure-lowering effects of this medication and can increase the risk of kidney problems, especially in older adults, people with kidney disease, or those who are dehydrated.<\/li>\n\n\n\n<li><strong>ACE inhibitors, other ARBs, and aliskiren:<\/strong> Because Amlodipine-valsartan-HCTZ already contains valsartan, combining it with other medications that affect the renin-angiotensin system, such as ACE inhibitors, other ARBs, or aliskiren, can increase the risk of low blood pressure, elevated potassium levels, and kidney problems. These combinations are generally avoided unless specifically recommended and monitored by a provider.<\/li>\n\n\n\n<li><strong>Cholesterol-lowering drugs:<\/strong> Amlodipine-valsartan-HCTZ can interact with certain cholesterol medications. Amlodipine may increase blood levels of simvastatin, which can raise the risk of statin-related side effects such as muscle pain or muscle injury. For this reason, the recommended simvastatin dose is generally limited to 20 mg daily when used with amlodipine. This interaction has not been observed with atorvastatin. Bile acid sequestrants, such as cholestyramine and colestipol, can reduce HCTZ absorption and should be taken at least 4 hours before or 4\u20136 hours after this medication.\u00a0<\/li>\n\n\n\n<li><strong>Phosphodiesterase-5 (PDE-5) inhibitors: <\/strong>Medications used to treat erectile dysfunction, such as sildenafil (Viagra), can enhance the blood pressure-lowering effects of amlodipine-valsartan-HCTZ and increase the risk of low blood pressure, dizziness, or lightheadedness.<\/li>\n\n\n\n<li><strong>Potassium supplements and salt substitutes:<\/strong> Taking these with amlodipine-valsartan-HCTZ may cause electrolyte imbalances. This combination is generally avoided unless specifically recommended and monitored by a provider<\/li>\n\n\n\n<li><strong>Immunosuppressants:<\/strong> Drugs like cyclosporine or tacrolimus can interact with amlodipine-valsartan-HCTZ. This combination may increase blood levels of uric acid and raise the risk of gout, and may also increase the risk of kidney problems.\u00a0<\/li>\n\n\n\n<li><strong>Lithium:<\/strong> This medication can interact with amlodipine-valsartan-HCTZ and may increase lithium levels in the blood, raising the risk of lithium toxicity.<\/li>\n\n\n\n<li><strong>Seizure medications: <\/strong>Certain antiseizure drugs can interact with amlodipine-valsartan-HCTZ in different ways. Carbamazepine may increase the risk of low sodium levels when used with hydrochlorothiazide. Barbiturates such as phenobarbital or primidone may enhance blood pressure-lowering effects, increasing the risk of dizziness or orthostatic hypotension.<\/li>\n\n\n\n<li><strong>Certain antibiotics and antifungals:<\/strong> Medications such as clarithromycin, ketoconazole, and itraconazole can increase blood levels of amlodipine. This may increase the risk of side effects such as low blood pressure, dizziness, lightheadedness, or swelling in the legs and feet.\u00a0<\/li>\n\n\n\n<li><strong>HIV\/AIDS or hepatitis medications: <\/strong>Antiviral medications such as ritonavir can increase blood levels of amlodipine and valsartan. This may increase the risk of side effects such as low blood pressure, dizziness, lightheadedness, and swelling in the legs or feet.<\/li>\n\n\n\n<li><strong>Muscle relaxants: <\/strong>Amlodipine-valsartan-HCTZ may increase the effects of certain muscle relaxants used during surgery, particularly nondepolarizing muscle relaxants. Patients should inform their surgical team that they are taking this medication before any procedure..<\/li>\n\n\n\n<li><strong>Diabetes medications: <\/strong>Insulin and oral diabetes medications can interact with amlodipine-valsartan-HCTZ. Hydrochlorothiazide may affect blood sugar control, and some patients may require adjustments to their diabetes medications.<\/li>\n\n\n\n<li><strong>Cancer medications: <\/strong>Certain cancer medications, including cyclophosphamide and methotrexate, can interact with amlodipine-valsartan-HCTZ. This combination may increase the risk of side effects, including low blood cell counts.<\/li>\n\n\n\n<li><strong>Digoxin: <\/strong>Amlodipine-valsartan-HCTZ can increase the risk of digoxin toxicity, particularly if hydrochlorothiazide causes low potassium or magnesium levels.\u00a0<\/li>\n\n\n\n<li><strong>Rifampin and St. John&#8217;s wort:<\/strong> Rifampin and the herbal supplement St. John&#8217;s wort can reduce blood levels of amlodipine, which may make amlodipine-valsartan-HCTZ less effective at lowering blood pressure.\u00a0<\/li>\n\n\n\n<li><strong>Alcohol:<\/strong> Alcohol can increase the blood pressure-lowering effect of this medication, which may cause dizziness, lightheadedness, or fainting, especially when standing up quickly.<\/li>\n<\/ul>\n\n\n\n<p>Always give your doctor and pharmacist a complete list of all your medications, vitamins, and supplements to check for potential interactions.<\/p>\n\n\n\n<section class=\"telyrx-faq-section\" data-toc-title=\"FAQs\">\n\t<h2 class=\"telyrx-faq-heading\">FAQs<\/h2>\n\t\t<div class=\"telyrx-faq-items\">\n\t\t\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Why is amlodipine-valsartan-HCTZ prescribed as a single pill instead of three separate medications?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Combining these three medications into a single daily tablet simplifies treatment, which can make it easier to take your medication as prescribed.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Can taking amlodipine-valsartan-HCTZ cause swelling in the ankles and feet?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Yes, swelling (edema) in the extremities \u2014 such as the legs, ankles, arms, and feet \u2014is a common side effect of amlodipine-valsartan-HCTZ. Elevating the legs or wearing compression socks may offer relief. The risk of swelling is generally lower than with amlodipine alone because valsartan can help counteract this effect.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Does amlodipine-valsartan-HCTZ interact with pain relievers like ibuprofen or naproxen?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Yes, there is a known interaction between amlodipine-valsartan-HCTZ and nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen. Taking them together can affect blood pressure control and increase the risk of kidney issues.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Does the hydrochlorothiazide in Exforge HCT increase the frequency of urination?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Yes, hydrochlorothiazide is a thiazide diuretic, or \u201cwater pill.\u201d It works by helping the kidneys remove excess fluid and sodium through your urine, which can cause you to urinate more often.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Can Exforge HCT cause a gout flare in the joints?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Yes, it is possible. The medication can raise uric acid levels in the bloodstream, which may trigger or worsen gout. Symptoms include severe pain, redness, and swelling, often affecting joints such as the big toe. People with a history of gout or kidney problems may have an increased risk of experiencing this side effect.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Is it safe to consume alcohol while taking amlodipine-valsartan-HCTZ?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>It is generally accepted that alcohol should be limited or avoided altogether while taking this medication. Alcohol can increase the risk of experiencing dizziness and lightheadedness. It can also disrupt blood pressure control.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Does Exforge HCT interact with cholesterol medications like simvastatin?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Yes, Exforge HCT is known to interact with simvastatin, a medication used to lower cholesterol. The amlodipine component can increase simvastatin levels in the blood, which may increase the risk of side effects. For this reason, the maximum recommended simvastatin dose is 20 mg daily when taken with Exforge HCT. Exforge HCT can also interact with cholesterol medications called bile acid sequestrants.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">What should I do if I experience a dry cough after starting amlodipine-valsartan-HCTZ?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>A dry cough is much less common with amlodipine-valsartan-HCTZ than with blood pressure medications that contain an ACE inhibitor. While cough and other cold-like symptoms have been reported with Exforge HCT, persistent or bothersome cough is not considered a typical side effect of valsartan. If you develop a new or ongoing dry cough after starting the medication, contact your healthcare provider to discuss possible causes and whether any changes to your treatment are needed.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Does Exforge HCT lower the resting heart rate like a beta-blocker?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Exforge HCT works by relaxing the blood vessels and removing excess fluid, rather than targeting heart rate as beta-blockers do. However, it can rarely cause an irregular or fluttering heartbeat, which should be reported to a physician immediately.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">What is the difference between the brand-name Exforge HCT and generic amlodipine-valsartan-HCTZ?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Exforge HCT is the brand-name version of the medication, while amlodipine-valsartan-HCTZ is the generic equivalent. Both contain the same three active ingredients in the same dosages and work identically in the body. The generic version is generally available at a much lower cost.<\/p>\n\n\t<\/div>\n<\/details>\n\n\t<\/div>\n<\/section>\n<script type=\"application\/ld+json\">{\"@context\":\"https:\/\/schema.org\",\"@type\":\"FAQPage\",\"mainEntity\":[{\"@type\":\"Question\",\"name\":\"Why is amlodipine-valsartan-HCTZ prescribed as a single pill instead of three separate medications?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Combining these three medications into a single daily tablet simplifies treatment, which can make it easier to take your medication as prescribed.\"}},{\"@type\":\"Question\",\"name\":\"Can taking amlodipine-valsartan-HCTZ cause swelling in the ankles and feet?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Yes, swelling (edema) in the extremities \u2014 such as the legs, ankles, arms, and feet \u2014is a common side effect of amlodipine-valsartan-HCTZ. Elevating the legs or wearing compression socks may offer relief. The risk of swelling is generally lower than with amlodipine alone because valsartan can help counteract this effect.\"}},{\"@type\":\"Question\",\"name\":\"Does amlodipine-valsartan-HCTZ interact with pain relievers like ibuprofen or naproxen?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Yes, there is a known interaction between amlodipine-valsartan-HCTZ and nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen. Taking them together can affect blood pressure control and increase the risk of kidney issues.\"}},{\"@type\":\"Question\",\"name\":\"Does the hydrochlorothiazide in Exforge HCT increase the frequency of urination?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Yes, hydrochlorothiazide is a thiazide diuretic, or \u201cwater pill.\u201d It works by helping the kidneys remove excess fluid and sodium through your urine, which can cause you to urinate more often.\"}},{\"@type\":\"Question\",\"name\":\"Can Exforge HCT cause a gout flare in the joints?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Yes, it is possible. The medication can raise uric acid levels in the bloodstream, which may trigger or worsen gout. Symptoms include severe pain, redness, and swelling, often affecting joints such as the big toe. People with a history of gout or kidney problems may have an increased risk of experiencing this side effect.\"}},{\"@type\":\"Question\",\"name\":\"Is it safe to consume alcohol while taking amlodipine-valsartan-HCTZ?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"It is generally accepted that alcohol should be limited or avoided altogether while taking this medication. Alcohol can increase the risk of experiencing dizziness and lightheadedness. It can also disrupt blood pressure control.\"}},{\"@type\":\"Question\",\"name\":\"Does Exforge HCT interact with cholesterol medications like simvastatin?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Yes, Exforge HCT is known to interact with simvastatin, a medication used to lower cholesterol. The amlodipine component can increase simvastatin levels in the blood, which may increase the risk of side effects. For this reason, the maximum recommended simvastatin dose is 20 mg daily when taken with Exforge HCT. Exforge HCT can also interact with cholesterol medications called bile acid sequestrants.\"}},{\"@type\":\"Question\",\"name\":\"What should I do if I experience a dry cough after starting amlodipine-valsartan-HCTZ?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"A dry cough is much less common with amlodipine-valsartan-HCTZ than with blood pressure medications that contain an ACE inhibitor. While cough and other cold-like symptoms have been reported with Exforge HCT, persistent or bothersome cough is not considered a typical side effect of valsartan. If you develop a new or ongoing dry cough after starting the medication, contact your healthcare provider to discuss possible causes and whether any changes to your treatment are needed.\"}},{\"@type\":\"Question\",\"name\":\"Does Exforge HCT lower the resting heart rate like a beta-blocker?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Exforge HCT works by relaxing the blood vessels and removing excess fluid, rather than targeting heart rate as beta-blockers do. However, it can rarely cause an irregular or fluttering heartbeat, which should be reported to a physician immediately.\"}},{\"@type\":\"Question\",\"name\":\"What is the difference between the brand-name Exforge HCT and generic amlodipine-valsartan-HCTZ?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Exforge HCT is the brand-name version of the medication, while amlodipine-valsartan-HCTZ is the generic equivalent. Both contain the same three active ingredients in the same dosages and work identically in the body. The generic version is generally available at a much lower cost.\"}}]}<\/script>\n\n<div class=\"telyrx-comparable-medications wp-block-telyrx-comparable-medications\">\n\t<h2 class=\"telyrx-comparable-medications__title\">Comparable Medications<\/h2>\n\t\t\t<div class=\"telyrx-comparable-medications__intro\">\n\n<p><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong>Amlodipine-valsartan-HCTZ, amlodipine-valsartan (Exforge), amlodipine-benazepril (Lotrel), or amlodipine-olmesartan-HCTZ (Tribenzor)?<\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/p>\n\n\n\n<p>There are several medications your doctor can prescribe instead of amlodipine-valsartan-HCTZ. Here are a few possible alternatives below.<\/p>\n\n<\/div>\n\t\t\t\t<div class=\"telyrx-comparable-medications__item\">\n\t\t\t<div class=\"telyrx-comparable-medications__item-top\">\n\t\t\t\t<div class=\"telyrx-comparable-medications__item-info\">\n\t\t\t\t\t<h3 class=\"telyrx-comparable-medications__name\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"telyrx-comparable-medications__name-link\" href=\"https:\/\/telyrx.com\/medications\/amlodipine-valsartan-tablets\">\n\t\t\t\t\t\t\t\tAmlodipine\/Valsartan Tablets\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/h3>\n\n\t\t\t\t\t\t\t\t\t\t\t<p class=\"telyrx-comparable-medications__price\">\n\t\t\t\t\t\t\tFrom $27.99\t\t\t\t\t\t<\/p>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<a class=\"telyrx-comparable-medications__cta\" href=\"https:\/\/telyrx.com\/medications\/amlodipine-valsartan-tablets\">\n\t\t\t\t\t\tView Product\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<p class=\"telyrx-comparable-medications__description\">\n\t\t\t\t\tA two-drug combination (CCB + ARB) without a diuretic. It may be used when blood pressure is controlled without the need for a \u201cwater pill,\u201d or when simplifying therapy. It is also less likely to cause leg swelling than amlodipine alone.\t\t\t\t<\/p>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<hr class=\"telyrx-comparable-medications__divider\">\n\t\t\t\t\t<div class=\"telyrx-comparable-medications__item\">\n\t\t\t<div class=\"telyrx-comparable-medications__item-top\">\n\t\t\t\t<div class=\"telyrx-comparable-medications__item-info\">\n\t\t\t\t\t<h3 class=\"telyrx-comparable-medications__name\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"telyrx-comparable-medications__name-link\" href=\"https:\/\/telyrx.com\/medications\/amlodipine-benazepril-capsules\">\n\t\t\t\t\t\t\t\tAmlodipine\/Benazepril Capsules\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/h3>\n\n\t\t\t\t\t\t\t\t\t\t\t<p class=\"telyrx-comparable-medications__price\">\n\t\t\t\t\t\t\tFrom $37.99\t\t\t\t\t\t<\/p>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<a class=\"telyrx-comparable-medications__cta\" href=\"https:\/\/telyrx.com\/medications\/amlodipine-benazepril-capsules\">\n\t\t\t\t\t\tView Product\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<p class=\"telyrx-comparable-medications__description\">\n\t\t\t\t\tA two-drug combination (CCB + ACE inhibitor). Compared with valsartan-based products, it is more likely to cause a dry cough and, rarely, angioedema due to the ACE inhibitor component.\t\t\t\t<\/p>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<hr class=\"telyrx-comparable-medications__divider\">\n\t\t\t\t\t<div class=\"telyrx-comparable-medications__item\">\n\t\t\t<div class=\"telyrx-comparable-medications__item-top\">\n\t\t\t\t<div class=\"telyrx-comparable-medications__item-info\">\n\t\t\t\t\t<h3 class=\"telyrx-comparable-medications__name\">\n\t\t\t\t\t\t\t\t\t\t\t\t\tAmlodipine-Olmesartan-HCTZ\t\t\t\t\t\t\t\t\t\t\t<\/h3>\n\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<p class=\"telyrx-comparable-medications__description\">\n\t\t\t\t\tA three-drug combination similar to Exforge HCT but uses olmesartan instead of valsartan. It also includes a diuretic and is generally reserved for patients who need multiple medications to control blood pressure.\t\t\t\t<\/p>\n\t\t\t\t\t<\/div>\n\n\t\t\t<\/div>\n\n\n<div class=\"telyrx-product-list telyrx-product-list--single wp-block-telyrx-product-list\">\n\t\t\t\t\t<a class=\"telyrx-product-list__card telyrx-product-list__card--single\" href=\"https:\/\/telyrx.com\/medications\/amlodipine-valsartan-hctz-tablets\">\n\t\t\t\t\t\t\t<img\n\t\t\t\t\tclass=\"telyrx-product-list__image\"\n\t\t\t\t\tsrc=\"https:\/\/telyrx.com\/media\/catalog\/product\/a\/m\/amlodipine_and_valsartan_tablets_usp_5mg_160mg_12.5mg_1.png\"\n\t\t\t\t\talt=\"Amlodipine \/ Valsartan \/ HCTZ Tablets\"\n\t\t\t\t\twidth=\"213\"\n\t\t\t\t\theight=\"213\"\n\t\t\t\t\tloading=\"lazy\"\n\t\t\t\t>\n\t\t\t\t\t\t<div class=\"telyrx-product-list__content\">\n\t\t\t\t<p class=\"telyrx-product-list__name\">Amlodipine \/ Valsartan \/ HCTZ Tablets<\/p>\n\t\t\t\t<span class=\"telyrx-product-list__cta telyrx-product-list__cta--yellow\">\n\t\t\t\t\tView Product\t\t\t\t<\/span>\n\t\t\t<\/div>\n\t\t<\/a>\n\t<\/div>\n\n\n<div class=\"telyrx-product-list-section alignfull wp-block-telyrx-product-list\">\n\t<h2 class=\"telyrx-product-list-section__heading\" data-toc-hidden=\"true\">We Have Amlodipine in Stock. Get Yours Today!<\/h2>\n\t<div class=\"telyrx-product-list telyrx-product-list--footer-multi\">\n\t\t<div class=\"telyrx-product-list__grid\">\n\t\t\t\t\t\t\t<a class=\"telyrx-product-list__card\" href=\"https:\/\/telyrx.com\/medications\/amlodipine-valsartan-hctz-tablets\">\n\t\t\t\t\t\t\t\t\t\t\t<img\n\t\t\t\t\t\t\tclass=\"telyrx-product-list__image\"\n\t\t\t\t\t\t\tsrc=\"https:\/\/telyrx.com\/media\/catalog\/product\/a\/m\/amlodipine_and_valsartan_tablets_usp_5mg_160mg_12.5mg_1.png\"\n\t\t\t\t\t\t\talt=\"Amlodipine \/ Valsartan \/ HCTZ Tablets\"\n\t\t\t\t\t\t\twidth=\"213\"\n\t\t\t\t\t\t\theight=\"213\"\n\t\t\t\t\t\t\tloading=\"lazy\"\n\t\t\t\t\t\t>\n\t\t\t\t\t\t\t\t\t\t<div class=\"telyrx-product-list__content\">\n\t\t\t\t\t\t<p class=\"telyrx-product-list__name\">Amlodipine \/ Valsartan \/ HCTZ Tablets<\/p>\n\t\t\t\t\t\t<span class=\"telyrx-product-list__cta telyrx-product-list__cta--yellow\">\n\t\t\t\t\t\t\tOrder Now\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/a>\n\t\t\t\t\t<\/div>\n\t<\/div>\n\t\t\t<div class=\"telyrx-product-list-section__extra\">\n\t\t\t<p class=\"has-muted-color has-text-color has-urbanist-font-family\" style=\"font-size:0.875rem;font-style:italic;font-weight:400;line-height:1.571\"><strong>Important:<\/strong> Information on this page is for educational purposes only. Prescribing decisions are made by independent, licensed providers. TelyRx operates technology-enabled pharmacies and a telehealth platform that connects patients with licensed providers. Prescriptions, when provider-approved and issued, are filled and shipped by TelyRx-affiliated pharmacies. We do not employ physicians or make prescribing decisions. Learn more about our editorial standards <a href=\"\/blog\/editorial-standards\/\">here<\/a>.<\/p>\t\t<\/div>\n\t<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Amlodipine-valsartan-hydrochlorothiazide (HCTZ) is an oral prescription medication used to treat high blood pressure (hypertension). It combines three first-choice blood pressure medications \u2014 a calcium channel blocker, an angiotensin II receptor blocker, and a thiazide diuretic \u2014 into a single daily tablet.<\/p>\n<p>Amlodipine-valsartan-HCTZ is often prescribed to people who require intensive blood pressure control or when single- or dual-medication therapies have not successfully achieved blood pressure goals. Common side effects include dizziness, headache, and swelling in the ankles, legs, or feet.<\/p>\n","protected":false},"author":2,"featured_media":9451,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"single-medication","format":"standard","meta":{"content-type":"","telyrx_subtitle":"Uses, Side Effects, Dosage & FAQs (2026 Guide)","telyrx_last_updated":"2026-06-29T11:31","telyrx_reviewer_name":"Andy Acevedo","telyrx_reviewer_credentials":"PharmD","telyrx_reviewer_job_title":"Pharmacist","telyrx_reviewer_affiliation":"TelyRx","telyrx_reviewer_url":"","telyrx_show_reviewer_job_title":"0","telyrx_show_reviewer_affiliation":"0","telyrx_show_toc":"1","telyrx_reviewer_bio":"","telyrx_reviewer_avatar":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","_telyrx_clean_url":"\/medications\/amlodipine-valsartan-hctz-tablets\/what-is\/"},"categories":[86],"tags":[],"class_list":["post-9450","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medications"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.6 (Yoast SEO v27.6) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>What Is Amlodipine-Valsartan-HCTZ? 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