{"id":8461,"date":"2026-05-08T19:11:53","date_gmt":"2026-05-08T19:11:53","guid":{"rendered":"https:\/\/telyrx.com\/blog\/?p=8461"},"modified":"2026-05-29T14:07:50","modified_gmt":"2026-05-29T14:07:50","slug":"what-is-trandolapril-tablets","status":"publish","type":"post","link":"https:\/\/telyrx.com\/blog\/medications\/what-is-trandolapril-tablets\/","title":{"rendered":"What Is Trandolapril?"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\" id=\"h-how-it-works\">How It Works<\/h2>\n\n\n\n<p>Trandolapril works by blocking the angiotensin-converting enzyme (ACE). Your body naturally produces angiotensin I, a largely inactive amino acid peptide, which ACE converts into angiotensin II, a vasoconstrictor that causes blood vessels to narrow. By blocking the ACE, trandolapril helps keep the blood vessels dilated and relaxed.<\/p>\n\n\n\n<p>By dilating blood vessels and increasing the space for blood to flow, the medication reduces pressure on the arterial walls. This means the heart does not need to pump as forcefully to move blood through the body.<\/p>\n\n\n\n<div class=\"quick-facts-card\">\n  <table class=\"quick-facts-table\">\n    <colgroup>\n      <col\/>\n      <col\/>\n    <\/colgroup>\n\n    <thead>\n      <tr>\n        <th colspan=\"2\">Quick Facts<\/th>\n      <\/tr>\n    <\/thead>\n\n    <tbody>\n      <tr>\n        <td><strong>Common Brands<\/strong><\/td>\n        <td>Mavik (largely discontinued)<\/td>\n      <\/tr>\n\n      <tr>\n         <td><strong>Drug Class<\/strong><\/td>\n        <td>Angiotensin-converting enzyme (ACE) inhibitor<\/td>\n      <\/tr>\n\n      <tr>\n        <td><strong>Generic Status<\/strong><\/td>\n        <td>Generic version available<\/td>\n      <\/tr>\n\n      <tr>\n         <td><strong>Availability<\/strong><\/td>\n        <td>Prescription only<\/td>\n    <\/tbody>\n  <\/table>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-dosing\">Dosing<\/h2>\n\n\n\n<p>Many patients begin taking trandolapril at a lower dose to allow their body time to adjust to the change in blood pressure. Providers may titrate or increase the dosage as needed.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Hypertension: <\/strong>The typical starting dose for trandolapril for high blood pressure is 1 mg once daily. Based on the patient&#8217;s response, their provider may increase the dosage to 2 mg or 4 mg per day.<\/li>\n\n\n\n<li><strong>Post-heart attack: <\/strong>Doctors usually begin post-heart attack patients at a dose of 0.5 mg to 1 mg per day. As long as the patient tolerates the medication, their provider may titrate their dose up to 4 mg per day.<\/li>\n\n\n\n<li><strong>Consistency: <\/strong>Per standard guidelines, patients are advised to take trandolapril at the same time each day to maintain steady medication levels in their systems.<\/li>\n\n\n\n<li><strong>Administration: <\/strong>Guidelines suggest swallowing the tablet whole with water, but it can be taken with or without food.<\/li>\n<\/ul>\n\n\n\n<p><em><strong>Note:<\/strong> The dosing information below is for educational purposes only. Your prescribing physician will determine your specific dose based on your individual health needs.&nbsp;Always follow your healthcare provider\u2019s instructions for exact dosing.<\/em><\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-uses\">Uses<\/h2>\n\n\n\n<p><strong>FDA-Approved Uses<\/strong><\/p>\n\n\n\n<p>Trandolapril is FDA-approved to lower blood pressure in people with hypertension, either as standalone therapy or in combination with other medications like thiazide diuretics.&nbsp;<\/p>\n\n\n\n<p>The drug is also FDA-approved to reduce the risk of death or hospitalization for patients who show signs of heart failure or left ventricular dysfunction after a heart attack.<\/p>\n\n\n\n<p><strong>Off-Label Uses<\/strong><\/p>\n\n\n\n<p>You may see trandolapril prescribed for uses that are not &#8220;FDA-approved.&#8221; This is a very common and legal practice called &#8220;off-label&#8221; prescribing, where a doctor uses their clinical judgment to prescribe a drug for a different (but well-researched) purpose.<\/p>\n\n\n\n<p>Common off-label uses for trandolapril currently found in clinical practice and research include:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Diabetic nephropathy: <\/strong>Providers may prescribe trandolapril to protect kidney function in people with diabetes, as ACE inhibitors can reduce protein leakage in the kidneys.<\/li>\n\n\n\n<li><strong>Chronic kidney disease: <\/strong>Trandolapril is frequently recommended to slow the progression of chronic kidney disease in non-diabetic patients with protein in their urine.<\/li>\n\n\n\n<li><strong>Stable coronary artery disease:<\/strong> Some providers may use trandolapril in certain cardiovascular management strategies for patients with stable coronary artery disease. Some providers use trandolapril to reduce the risk of future cardiovascular events in people with known arterial blockages, even if they do not have heart failure.<\/li>\n<\/ul>\n\n\n<div class=\"telyrx-email-cta telyrx-email-cta--banner alignfull wp-block-telyrx-email-signup\">\n\t\t<h2 class=\"telyrx-email-cta__heading\" data-toc-hidden=\"true\">Get Savings Updates<\/h2>\n\t<p class=\"telyrx-email-cta__description\">Join our mailing list for exclusive deals and more.<\/p>\n\t\t\t<form\n\t\t\tid=\"telyrx-email-form-1\"\n\t\t\tclass=\"telyrx-email-cta__form\"\n\t\t\tdata-portal-id=\"46401311\"\n\t\t\tdata-form-id=\"14e1d7d5-6b17-4228-b42e-c06d1a6c240b\"\n\t\t\tdata-i18n=\"{&quot;subscribe&quot;:&quot;Subscribe&quot;,&quot;success&quot;:&quot;Thanks! You&#039;re subscribed.&quot;,&quot;error&quot;:&quot;Something went wrong. Please try again.&quot;}\"\n\t\t>\n\t\t\t<div class=\"telyrx-email-cta__pill\">\n\t\t\t\t<input\n\t\t\t\t\ttype=\"email\"\n\t\t\t\t\tname=\"email\"\n\t\t\t\t\tclass=\"telyrx-email-cta__input\"\n\t\t\t\t\tplaceholder=\"Enter your email\"\n\t\t\t\t\trequired\n\t\t\t\t\tautocomplete=\"email\"\n\t\t\t\t\/>\n\t\t\t\t<button type=\"submit\" class=\"telyrx-email-cta__button\">\n\t\t\t\t\tSubscribe\t\t\t\t<\/button>\n\t\t\t<\/div>\n\t\t\t<p class=\"telyrx-email-cta__status\" aria-live=\"polite\"><\/p>\n\t\t<\/form>\n\t\t<noscript>\n\t\t\t<p class=\"telyrx-email-cta__noscript\">Please enable JavaScript to use the signup form.<\/p>\n\t\t<\/noscript>\n\t<\/div>\n\n\n\n<section class=\"telyrx-side-effects\" data-toc-title=\"Side Effects\">\n\t<h2 class=\"telyrx-side-effects__heading\">Side Effects<\/h2>\n\t<hr class=\"telyrx-side-effects__separator\">\n\t<div class=\"telyrx-side-effects__content\">\n\t\t\n\n<p>Most trandolapril side effects are mild, and will gradually diminish as the patient adapts to their new medication.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-common-side-effects\">Common Side Effects<\/h3>\n\n\n\n<div class=\"telyrx-side-effects-chip telyrx-side-effects-chip--common\">\n\t\n\n<p>Common side effects from taking trandolapril include:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Dry cough<\/li>\n\n\n\n<li>Dizziness and lightheadedness<\/li>\n\n\n\n<li>Fatigue<\/li>\n\n\n\n<li>Mild diarrhea, indigestion, or nausea<\/li>\n<\/ul>\n\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-serious-side-effects\">Serious Side Effects<\/h3>\n\n\n\n<div class=\"telyrx-side-effects-chip telyrx-side-effects-chip--serious\">\n\t\n\n<p>Serious side effects are rare, but it&#8217;s important to know what to look for if they do occur. Serious side effects from taking trandolapril can include:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Angioedema: <\/strong>Trandolapril has been associated with this serious reaction, which involves rapid swelling of the face, lips, tongue, and throat. This can be a life-threatening emergency if swelling blocks the airway.<\/li>\n\n\n\n<li><strong>Hyperkalemia: <\/strong>Trandolapril can cause the body to retain potassium, which can lead to unhealthy hyperkalemic levels. Symptoms include muscle weakness, nausea, and an irregular heartbeat.<\/li>\n\n\n\n<li><strong>Kidney impairment: <\/strong>While trandolapril is protective of the kidneys, it may cause a sudden decline in kidney function. This is especially common in people with pre-existing renal artery stenosis.<\/li>\n\n\n\n<li><strong>Liver toxicity: <\/strong>In rare cases, taking trandolapril can lead to liver toxicity. Key signs include jaundice (yellowing) of the skin and eyes, and elevated liver enzymes.<\/li>\n<\/ul>\n\n<\/div>\n\n\n\n<p class=\"has-muted-color has-text-color\" style=\"font-size:0.875rem\"><em>Call your doctor immediately if you experience any concerning or prolonged symptoms.<\/em><\/p>\n\n\t<\/div>\n<\/section>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-pharmacist-tips\">Pharmacist Tips<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-stand-up-slowly\">Stand Up Slowly<\/h3>\n\n\n\n<p>Since trandolapril lowers blood pressure, it can cause dizziness if you stand up too quickly. It is advisable to stand slowly from a sitting or lying position, especially during the first couple of weeks of treatment.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-watch-for-the-ace-cough\">Watch For The ACE Cough<\/h3>\n\n\n\n<p>ACE inhibitors like trandolapril are associated with a persistent dry cough. Rather than using cough syrup to treat this side effect, patients are advised to talk to their doctor about switching to a different type of medication.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-stay-hydrated\">Stay Hydrated<\/h3>\n\n\n\n<p>Lack of hydration can increase the risk of your blood pressure dropping too low or cause kidney strain. While on trandolapril, it is recommended to stay fully hydrated throughout the day to prevent these side effects.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-monitor-blood-pressure-at-home\">Monitor Blood Pressure At Home<\/h3>\n\n\n\n<p>A log of your blood pressure readings at home can be a valuable resource for your provider and help them determine your optimal trandolapril dosage.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-avoid-salt-substitutes\">Avoid Salt Substitutes<\/h3>\n\n\n\n<p>Many salt substitutes swap sodium for potassium. As trandolapril can already increase potassium retention, taking the drug alongside these salt substitutes can lead to dangerous levels<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-drug-interactions\">Drug Interactions<\/h2>\n\n\n\n<p>As a medication processed in the kidneys, trandolapril can interact with a wide range of other drugs and other substances. Known interactions with trandolapril include:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Potassium supplements: <\/strong>Taking trandolapril with potassium pills or potassium-sparing diuretics can significantly increase the risk of unhealthy potassium buildup and heart rhythm issues.<\/li>\n\n\n\n<li><strong>Nonsteroidal anti-inflammatory drugs (NSAIDs): <\/strong>Common NSAID pain relievers like ibuprofen and naproxen can interfere with trandolapril&#8217;s ability to lower blood pressure and increase the risk of kidney damage.<\/li>\n\n\n\n<li><strong>Lithium: <\/strong>Trandolapril can increase the levels of lithium in your blood, potentially leading to toxicity.<\/li>\n\n\n\n<li><strong>Entresto: <\/strong>Per standard guidelines, patients are advised to wait at least 36 hours after stopping trandolapril before starting Entresto. Taking these heart failure medications too closely together greatly increases the risk of angioedema.<\/li>\n<\/ul>\n\n\n\n<p>Always give your doctor and pharmacist a complete list of all your medications, vitamins, and supplements to check for potential interactions.<\/p>\n\n\n\n<section class=\"telyrx-faq-section\" data-toc-title=\"FAQs\">\n\t<h2 class=\"telyrx-faq-heading\">FAQs<\/h2>\n\t\t<div class=\"telyrx-faq-items\">\n\t\t\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">What time of day should I take trandolapril?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Many providers recommend taking trandolapril in the morning to help manage blood pressure throughout the day. However, taking this medication consistently at the same time each day is more crucial to effective treatment than taking it at a certain time of day.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Do I need to take this pill with a meal?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>No, standard guidelines for trandolapril state the drug may be taken with or without food. If you experience nausea or gastrointestinal discomfort after taking the medication on an empty stomach, timing your next dose with a light meal or snack may help you avoid these side effects.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Is it normal to feel dizzy or lightheaded when standing up during the first week of taking this?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Yes, it is normal to feel dizzy or lightheaded after standing up when you take trandolapril, especially during the first week of treatment. These side effects indicate your body is adjusting to the new blood pressure. If you still feel dizzy or lightheaded after a few weeks of taking the drug, a follow-up appointment with your provider is recommended.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Can I cut or split this tablet in half?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Standard guidelines recommend swallowing the trandolapril tablet whole to ensure the medication is properly absorbed and released within your body. It is not recommended to split it in half.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">What should I do if I forget my morning dose?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>If a patient forgets their morning trandolapril dose, standard guidelines suggest taking the tablet as soon as they remember. If it is almost time for their next dose, they are advised to skip the missed dose and resume treatment<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Is it safe to eat high-potassium foods while taking this?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Per standard guidelines, moderate intake of foods such as bananas and oranges is generally considered safe for healthy people taking trandolapril. However, avoid consuming large quantities of potassium-rich food, taking potassium supplements, or using potassium-based salt substitutes without first talking to their provider.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Is it safe to drink alcohol while taking trandolapril?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Alcohol can lower blood pressure, so drinking while taking trandolapril can enhance the drug&#8217;s effects and lead to a steep blood pressure drop. Limited or no alcohol intake while on trandolapril is generally recommended.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Will I experience a rebound spike in blood pressure if I run out of pills?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Trandolapril does not cause a pronounced rebound effect after discontinuing use, but quitting the drug abruptly can still lead your blood pressure to return to its pre-treatment levels and pose a risk to your cardiovascular health.<\/p>\n\n\t<\/div>\n<\/details>\n\n\t<\/div>\n<\/section>\n<script type=\"application\/ld+json\">{\"@context\":\"https:\/\/schema.org\",\"@type\":\"FAQPage\",\"mainEntity\":[{\"@type\":\"Question\",\"name\":\"What time of day should I take trandolapril?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Many providers recommend taking trandolapril in the morning to help manage blood pressure throughout the day. However, taking this medication consistently at the same time each day is more crucial to effective treatment than taking it at a certain time of day.\"}},{\"@type\":\"Question\",\"name\":\"Do I need to take this pill with a meal?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"No, standard guidelines for trandolapril state the drug may be taken with or without food. If you experience nausea or gastrointestinal discomfort after taking the medication on an empty stomach, timing your next dose with a light meal or snack may help you avoid these side effects.\"}},{\"@type\":\"Question\",\"name\":\"Is it normal to feel dizzy or lightheaded when standing up during the first week of taking this?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Yes, it is normal to feel dizzy or lightheaded after standing up when you take trandolapril, especially during the first week of treatment. These side effects indicate your body is adjusting to the new blood pressure. If you still feel dizzy or lightheaded after a few weeks of taking the drug, a follow-up appointment with your provider is recommended.\"}},{\"@type\":\"Question\",\"name\":\"Can I cut or split this tablet in half?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Standard guidelines recommend swallowing the trandolapril tablet whole to ensure the medication is properly absorbed and released within your body. It is not recommended to split it in half.\"}},{\"@type\":\"Question\",\"name\":\"What should I do if I forget my morning dose?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"If a patient forgets their morning trandolapril dose, standard guidelines suggest taking the tablet as soon as they remember. If it is almost time for their next dose, they are advised to skip the missed dose and resume treatment\"}},{\"@type\":\"Question\",\"name\":\"Is it safe to eat high-potassium foods while taking this?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Per standard guidelines, moderate intake of foods such as bananas and oranges is generally considered safe for healthy people taking trandolapril. However, avoid consuming large quantities of potassium-rich food, taking potassium supplements, or using potassium-based salt substitutes without first talking to their provider.\"}},{\"@type\":\"Question\",\"name\":\"Is it safe to drink alcohol while taking trandolapril?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Alcohol can lower blood pressure, so drinking while taking trandolapril can enhance the drug's effects and lead to a steep blood pressure drop. Limited or no alcohol intake while on trandolapril is generally recommended.\"}},{\"@type\":\"Question\",\"name\":\"Will I experience a rebound spike in blood pressure if I run out of pills?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Trandolapril does not cause a pronounced rebound effect after discontinuing use, but quitting the drug abruptly can still lead your blood pressure to return to its pre-treatment levels and pose a risk to your cardiovascular health.\"}}]}<\/script>\n\n<div class=\"telyrx-comparable-medications wp-block-telyrx-comparable-medications\">\n\t<h2 class=\"telyrx-comparable-medications__title\">Comparable Medications<\/h2>\n\t\t\t<div class=\"telyrx-comparable-medications__intro\">\n\n<p><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong>Trandolapril, Lisinopril, Losartan, Valsartan, or Sacubitril\/Valsartan?<\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/p>\n\n\n\n<p>Trandolapril is a prescription-strength ACE inhibitor medication used to lower blood pressure in people with hypertension and manage symptoms to reduce the risk of death or hospitalization in people with heart failure. Other drugs also serve these purposes, so your provider may recommend an alternative to trandolapril based on factors like your age, medical history, and severity of symptoms. Trandolapril alternatives include:<\/p>\n\n<\/div>\n\t\t\t\t<div class=\"telyrx-comparable-medications__item\">\n\t\t\t<div class=\"telyrx-comparable-medications__item-top\">\n\t\t\t\t<div class=\"telyrx-comparable-medications__item-info\">\n\t\t\t\t\t<h3 class=\"telyrx-comparable-medications__name\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"telyrx-comparable-medications__name-link\" href=\"https:\/\/telyrx.com\/medications\/lisinopril\">\n\t\t\t\t\t\t\t\tLisinopril\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/h3>\n\n\t\t\t\t\t\t\t\t\t\t\t<p class=\"telyrx-comparable-medications__price\">\n\t\t\t\t\t\t\tFrom $24.99\t\t\t\t\t\t<\/p>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<a class=\"telyrx-comparable-medications__cta\" href=\"https:\/\/telyrx.com\/medications\/lisinopril\">\n\t\t\t\t\t\tView Product\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<p class=\"telyrx-comparable-medications__description\">\n\t\t\t\t\tLike trandolapril, lisinopril is an ACE inhibitor primarily used to lower blood pressure. Lisinopril is fat-soluble, potentially allowing the drug to penetrate deeper into tissues and the vascular wall than trandolapril, which is processed in the kidneys. This means lisinopril can offer a longer duration of action in some patients.\t\t\t\t<\/p>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<hr class=\"telyrx-comparable-medications__divider\">\n\t\t\t\t\t<div class=\"telyrx-comparable-medications__item\">\n\t\t\t<div class=\"telyrx-comparable-medications__item-top\">\n\t\t\t\t<div class=\"telyrx-comparable-medications__item-info\">\n\t\t\t\t\t<h3 class=\"telyrx-comparable-medications__name\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"telyrx-comparable-medications__name-link\" href=\"https:\/\/telyrx.com\/medications\/losartan\">\n\t\t\t\t\t\t\t\tLosartan\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/h3>\n\n\t\t\t\t\t\t\t\t\t\t\t<p class=\"telyrx-comparable-medications__price\">\n\t\t\t\t\t\t\tFrom $24.99\t\t\t\t\t\t<\/p>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<a class=\"telyrx-comparable-medications__cta\" href=\"https:\/\/telyrx.com\/medications\/losartan\">\n\t\t\t\t\t\tView Product\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<p class=\"telyrx-comparable-medications__description\">\n\t\t\t\t\tBoth losartan and valsartan are both angiotensin II receptor blockers (ARBs), meaning they lower blood pressure by inhibiting production of angiotensin II without targeting the angiotensin-converting enzyme (ACE). ARBs, such as losartan and valsartan, are generally associated with a lower risk of cough than ACE inhibitors like trandolapril.\t\t\t\t<\/p>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<hr class=\"telyrx-comparable-medications__divider\">\n\t\t\t\t\t<div class=\"telyrx-comparable-medications__item\">\n\t\t\t<div class=\"telyrx-comparable-medications__item-top\">\n\t\t\t\t<div class=\"telyrx-comparable-medications__item-info\">\n\t\t\t\t\t<h3 class=\"telyrx-comparable-medications__name\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"telyrx-comparable-medications__name-link\" href=\"https:\/\/telyrx.com\/medications\/sacubitril-valsartan-tablets\">\n\t\t\t\t\t\t\t\tSacubitril \/ Valsartan Tablets\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/h3>\n\n\t\t\t\t\t\t\t\t\t\t\t<p class=\"telyrx-comparable-medications__price\">\n\t\t\t\t\t\t\tFrom $79.99\t\t\t\t\t\t<\/p>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<a class=\"telyrx-comparable-medications__cta\" href=\"https:\/\/telyrx.com\/medications\/sacubitril-valsartan-tablets\">\n\t\t\t\t\t\tView Product\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<p class=\"telyrx-comparable-medications__description\">\n\t\t\t\t\tThis combination drug is sold under the brand name Entresto and used to manage advanced heart failure. It contains a different type of inhibitor. Standard guidelines caution patients not to take Entresto within 36 hours of their last trandolapril dose, as taking both drugs together significantly increases the risk of angioedema.\t\t\t\t<\/p>\n\t\t\t\t\t<\/div>\n\n\t\t\t<\/div>\n\n\n<div class=\"telyrx-product-list telyrx-product-list--single wp-block-telyrx-product-list\">\n\t\t\t\t\t<a class=\"telyrx-product-list__card telyrx-product-list__card--single\" href=\"https:\/\/telyrx.com\/medications\/trandolapril-tablets\">\n\t\t\t\t\t\t\t<img\n\t\t\t\t\tclass=\"telyrx-product-list__image\"\n\t\t\t\t\tsrc=\"https:\/\/telyrx.com\/media\/catalog\/product\/t\/r\/trandolapril_tablets_2mg_tablets_2931_001_sq-bg_ai_gen_1.png\"\n\t\t\t\t\talt=\"Trandolapril Tablets\"\n\t\t\t\t\twidth=\"213\"\n\t\t\t\t\theight=\"213\"\n\t\t\t\t\tloading=\"lazy\"\n\t\t\t\t>\n\t\t\t\t\t\t<div class=\"telyrx-product-list__content\">\n\t\t\t\t<p class=\"telyrx-product-list__name\">Trandolapril Tablets<\/p>\n\t\t\t\t<span class=\"telyrx-product-list__cta telyrx-product-list__cta--yellow\">\n\t\t\t\t\tView Product\t\t\t\t<\/span>\n\t\t\t<\/div>\n\t\t<\/a>\n\t<\/div>\n\n\n<div class=\"telyrx-product-list-section alignfull wp-block-telyrx-product-list\">\n\t<h2 class=\"telyrx-product-list-section__heading\" data-toc-hidden=\"true\">We Have Trandolapril in Stock. Get Yours Today!<\/h2>\n\t<div class=\"telyrx-product-list telyrx-product-list--footer-multi\">\n\t\t<div class=\"telyrx-product-list__grid\">\n\t\t\t\t\t\t\t<a class=\"telyrx-product-list__card\" href=\"https:\/\/telyrx.com\/medications\/trandolapril-tablets\">\n\t\t\t\t\t\t\t\t\t\t\t<img\n\t\t\t\t\t\t\tclass=\"telyrx-product-list__image\"\n\t\t\t\t\t\t\tsrc=\"https:\/\/telyrx.com\/media\/catalog\/product\/t\/r\/trandolapril_tablets_2mg_tablets_2931_001_sq-bg_ai_gen_1.png\"\n\t\t\t\t\t\t\talt=\"Trandolapril Tablets\"\n\t\t\t\t\t\t\twidth=\"213\"\n\t\t\t\t\t\t\theight=\"213\"\n\t\t\t\t\t\t\tloading=\"lazy\"\n\t\t\t\t\t\t>\n\t\t\t\t\t\t\t\t\t\t<div class=\"telyrx-product-list__content\">\n\t\t\t\t\t\t<p class=\"telyrx-product-list__name\">Trandolapril Tablets<\/p>\n\t\t\t\t\t\t<span class=\"telyrx-product-list__cta telyrx-product-list__cta--yellow\">\n\t\t\t\t\t\t\tOrder Now\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/a>\n\t\t\t\t\t<\/div>\n\t<\/div>\n\t\t\t<div class=\"telyrx-product-list-section__extra\">\n\t\t\t<p class=\"has-muted-color has-text-color has-urbanist-font-family\" style=\"font-size:0.875rem;font-style:italic;font-weight:400;line-height:1.571\"><strong>Important:<\/strong> Information on this page is for educational purposes only. Prescribing decisions are made by independent, licensed providers. TelyRx operates technology-enabled pharmacies and a telehealth platform that connects patients with licensed providers. Prescriptions, when provider-approved and issued, are filled and shipped by TelyRx-affiliated pharmacies. We do not employ physicians or make prescribing decisions. Learn more about our editorial standards <a href=\"\/blog\/editorial-standards\/\">here<\/a>.<\/p>\t\t<\/div>\n\t<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Trandolapril is a prescription-strength oral medication primarily used to treat hypertension, or high blood pressure. It can also provide therapeutic benefits to people who have recently experienced a heart attack that has left them with heart failure or reduced their heart&#8217;s ability to pump blood effectively.<\/p>\n<p>Classified as an angiotensin-converting enzyme (ACE) inhibitor, trandolapril is most commonly prescribed as an oral tablet. The brand-name version, Mavik, has been largely discontinued, but the drug is widely available as a generic medication.<\/p>\n","protected":false},"author":2,"featured_media":8469,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"single-medication","format":"standard","meta":{"content-type":"","telyrx_subtitle":"Uses, Side Effects, Dosage & FAQs (2026 Guide)","telyrx_last_updated":"2026-05-08T19:11","telyrx_reviewer_name":"Nicholas Sesto","telyrx_reviewer_credentials":"PharmD","telyrx_reviewer_job_title":"Pharmacist","telyrx_reviewer_affiliation":"TelyRx","telyrx_reviewer_url":"","telyrx_show_reviewer_job_title":"0","telyrx_show_reviewer_affiliation":"0","telyrx_show_toc":"1","telyrx_reviewer_bio":"","telyrx_reviewer_avatar":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","_telyrx_clean_url":"\/medications\/trandolapril-tablets\/what-is\/"},"categories":[86],"tags":[],"class_list":["post-8461","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medications"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.6 (Yoast SEO v27.6) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>What Is Trandolapril? Uses, Side Effects, Dosage, and FAQs<\/title>\n<meta name=\"description\" content=\"Learn what trandolapril is, how it works, common side effects, and how to get it prescribed online through TelyRx.com\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/telyrx.com\/blog\/medications\/what-is-trandolapril-tablets\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"What Is Trandolapril?\" \/>\n<meta property=\"og:description\" content=\"Learn what trandolapril is, how it works, common side effects, and how to get it prescribed online through TelyRx.com\" \/>\n<meta property=\"og:url\" content=\"https:\/\/telyrx.com\/blog\/medications\/what-is-trandolapril-tablets\/\" \/>\n<meta property=\"og:site_name\" content=\"TelyRx Blog\" \/>\n<meta property=\"article:published_time\" content=\"2026-05-08T19:11:53+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-05-29T14:07:50+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/telyrx.com\/blog\/wp-content\/uploads\/2026\/05\/trandolapril_tablets_2mg_tablets_2931_001_sq-bg_ai_gen_1.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"900\" \/>\n\t<meta property=\"og:image:height\" content=\"900\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Mariah Powers\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Mariah Powers\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"7 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/medications\\\/what-is-trandolapril-tablets\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/medications\\\/what-is-trandolapril-tablets\\\/\"},\"author\":{\"name\":\"Mariah Powers\",\"@id\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/#\\\/schema\\\/person\\\/f1042a29c24ab7dd3c5f0fff9a06746b\"},\"headline\":\"What Is Trandolapril?\",\"datePublished\":\"2026-05-08T19:11:53+00:00\",\"dateModified\":\"2026-05-08T19:11:53+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/medications\\\/what-is-trandolapril-tablets\\\/\"},\"wordCount\":1472,\"publisher\":{\"@id\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/medications\\\/what-is-trandolapril-tablets\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/wp-content\\\/uploads\\\/2026\\\/05\\\/trandolapril_tablets_2mg_tablets_2931_001_sq-bg_ai_gen_1.jpg\",\"articleSection\":[\"Medications\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/medications\\\/what-is-trandolapril-tablets\\\/\",\"url\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/medications\\\/what-is-trandolapril-tablets\\\/\",\"name\":\"What Is Trandolapril? Uses, Side Effects, Dosage, and FAQs\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/medications\\\/what-is-trandolapril-tablets\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/medications\\\/what-is-trandolapril-tablets\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/wp-content\\\/uploads\\\/2026\\\/05\\\/trandolapril_tablets_2mg_tablets_2931_001_sq-bg_ai_gen_1.jpg\",\"datePublished\":\"2026-05-08T19:11:53+00:00\",\"dateModified\":\"2026-05-29T14:07:50+00:00\",\"description\":\"Learn what trandolapril is, how it works, common side effects, and how to get it prescribed online through TelyRx.com\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/medications\\\/what-is-trandolapril-tablets\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/telyrx.com\\\/blog\\\/medications\\\/what-is-trandolapril-tablets\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/medications\\\/what-is-trandolapril-tablets\\\/#primaryimage\",\"url\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/wp-content\\\/uploads\\\/2026\\\/05\\\/trandolapril_tablets_2mg_tablets_2931_001_sq-bg_ai_gen_1.jpg\",\"contentUrl\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/wp-content\\\/uploads\\\/2026\\\/05\\\/trandolapril_tablets_2mg_tablets_2931_001_sq-bg_ai_gen_1.jpg\",\"width\":900,\"height\":900,\"caption\":\"What Is Trandolapril?\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/medications\\\/what-is-trandolapril-tablets\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"TelyRx Blog\",\"item\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"What Is Trandolapril?\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/#website\",\"url\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/\",\"name\":\"TelyRx Blog\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/#organization\",\"name\":\"TelyRx Blog\",\"url\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/wp-content\\\/uploads\\\/2025\\\/02\\\/TelyRx-color-with-tag-1.png\",\"contentUrl\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/wp-content\\\/uploads\\\/2025\\\/02\\\/TelyRx-color-with-tag-1.png\",\"width\":227,\"height\":72,\"caption\":\"TelyRx Blog\"},\"image\":{\"@id\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/#\\\/schema\\\/logo\\\/image\\\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/#\\\/schema\\\/person\\\/f1042a29c24ab7dd3c5f0fff9a06746b\",\"name\":\"Mariah Powers\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/734649c70b9e51c3bd1d106626c4a11df0b8c186e9bb7a270c1df74bfa7fd018?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/734649c70b9e51c3bd1d106626c4a11df0b8c186e9bb7a270c1df74bfa7fd018?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/734649c70b9e51c3bd1d106626c4a11df0b8c186e9bb7a270c1df74bfa7fd018?s=96&d=mm&r=g\",\"caption\":\"Mariah Powers\"},\"description\":\"Mariah Powers is a wellness content strategist and writer with over seven years' experience developing clear, informative narratives on complex health topics for pharmaceutical manufacturers, hospitals, therapy clinics, and clean-living companies. 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