{"id":8360,"date":"2026-05-08T12:13:53","date_gmt":"2026-05-08T12:13:53","guid":{"rendered":"https:\/\/telyrx.com\/blog\/?p=8360"},"modified":"2026-05-08T12:14:09","modified_gmt":"2026-05-08T12:14:09","slug":"what-is-prevident-5000-toothpaste","status":"publish","type":"post","link":"https:\/\/telyrx.com\/blog\/medications\/what-is-prevident-5000-toothpaste\/","title":{"rendered":"What Is PreviDent 5000 Toothpaste?"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\" id=\"h-how-it-works\">How It Works<\/h2>\n\n\n\n<p>To understand how PreviDent 5000 protects your teeth, it helps to think of your enamel as a shield that is constantly under attack. Every day, the bacteria in your mouth create acid that softens this shield.<\/p>\n\n\n\n<p>PreviDent 5000 helps protect teeth through a few steps:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Rebuilding the shield:<\/strong> When you brush, the high levels of fluoride act like a repair kit. They fill in tiny, microscopic weak spots in your enamel before they can turn into cavities.<\/li>\n\n\n\n<li><strong>Making teeth acid-proof:<\/strong> The new surface created by the fluoride is tougher than normal tooth enamel.\u00a0<\/li>\n\n\n\n<li><strong>Slowing down germs:<\/strong> The concentrated fluoride makes it difficult for plaque bacteria to create the harmful acid that causes decay.<\/li>\n<\/ul>\n\n\n\n<p>For people with sensitive teeth, some versions of PreviDent also include an ingredient that alters the tiny nerve pathways inside the tooth. This helps stop the sharp pain you might feel when drinking ice water or hot coffee.<\/p>\n\n\n\n<div class=\"quick-facts-card\">\n  <table class=\"quick-facts-table\">\n    <colgroup>\n      <col\/>\n      <col\/>\n    <\/colgroup>\n\n    <thead>\n      <tr>\n        <th colspan=\"2\">Quick Facts<\/th>\n      <\/tr>\n    <\/thead>\n\n    <tbody>\n      <tr>\n        <td><strong>Common Brands<\/strong><\/td>\n        <td>PreviDent 5000 Booster Plus, PreviDent 5000 Enamel Protect, PreviDent 5000 Sensitive<\/td>\n      <\/tr>\n\n      <tr>\n         <td><strong>Drug Class<\/strong><\/td>\n        <td>Dental fluoride<\/td>\n      <\/tr>\n\n      <tr>\n        <td><strong>Generic Status<\/strong><\/td>\n        <td>Generic version available<\/td>\n      <\/tr>\n\n      <tr>\n         <td><strong>Availability<\/strong><\/td>\n        <td>Prescription only<\/td>\n    <\/tbody>\n  <\/table>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-dosing\">Dosing<\/h2>\n\n\n\n<p>PreviDent 5000 is used in place of your regular toothpaste. For it to work correctly, the fluoride needs time to stay in contact with your teeth.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Frequency:<\/strong> Most dentists recommend using it once or twice a day.<\/li>\n\n\n\n<li><strong>Best time to use:<\/strong> If you use it once a day, the generally accepted best time is right before bed. This allows the fluoride to sit on your teeth all night while you sleep.<\/li>\n\n\n\n<li><strong>Amount: <\/strong>It is generally advised to use a thin ribbon of paste on a soft-bristle toothbrush.<\/li>\n\n\n\n<li><strong>Technique:<\/strong> Standard guidelines typically recommend brushing thoroughly for at least two minutes to ensure all surfaces are covered.<\/li>\n\n\n\n<li><strong>The no-rinse rule: <\/strong>After brushing, providers generally advise thoroughly spitting out the paste, but do not rinse your mouth with water. Standard guidelines suggest waiting at least 30 minutes before eating or drinking anything.<\/li>\n<\/ul>\n\n\n\n<p><em><strong>Note:<\/strong> Dosing information below is educational only. Your prescribing physician will determine your specific dose based on your individual health needs.\u00a0Always follow your healthcare provider\u2019s instructions for exact dosing.<\/em><\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-uses\">Uses<\/h2>\n\n\n\n<p><strong>FDA-Approved Uses<\/strong><\/p>\n\n\n\n<p>The FDA approves PreviDent 5000 toothpaste for:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Prevention of cavities:<\/strong> Reducing the risk of new tooth decay in high-risk patients.<\/li>\n\n\n\n<li><strong>Sensitivity relief:<\/strong> Managing pain from sensitive teeth (in specific formulas).<\/li>\n<\/ul>\n\n\n\n<p><strong>Off-Label Uses<\/strong><\/p>\n\n\n\n<p>You may see PreviDent 5000 prescribed for uses that are not FDA-approved. This is a common and legal practice called off-label prescribing, where a doctor uses their clinical judgment to prescribe a drug for a different (but well-researched) purpose.<\/p>\n\n\n\n<p>PreviDent 5000 toothpaste may be prescribed for the following conditions:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Reversing white spots:<\/strong> Dentists may use it to fix chalky white marks on teeth that appear after braces are removed.<\/li>\n\n\n\n<li><strong>Dry mouth protection:<\/strong> It is commonly used for patients who have lost saliva flow due to certain health conditions or medications.<\/li>\n<\/ul>\n\n\n<div class=\"telyrx-email-cta telyrx-email-cta--banner alignfull wp-block-telyrx-email-signup\">\n\t\t<h2 class=\"telyrx-email-cta__heading\" data-toc-hidden=\"true\">Get Savings Updates<\/h2>\n\t<p class=\"telyrx-email-cta__description\">Join our mailing list for exclusive deals and more.<\/p>\n\t\t\t<form\n\t\t\tid=\"telyrx-email-form-1\"\n\t\t\tclass=\"telyrx-email-cta__form\"\n\t\t\tdata-portal-id=\"46401311\"\n\t\t\tdata-form-id=\"14e1d7d5-6b17-4228-b42e-c06d1a6c240b\"\n\t\t\tdata-i18n=\"{&quot;subscribe&quot;:&quot;Subscribe&quot;,&quot;success&quot;:&quot;Thanks! You&#039;re subscribed.&quot;,&quot;error&quot;:&quot;Something went wrong. Please try again.&quot;}\"\n\t\t>\n\t\t\t<div class=\"telyrx-email-cta__pill\">\n\t\t\t\t<input\n\t\t\t\t\ttype=\"email\"\n\t\t\t\t\tname=\"email\"\n\t\t\t\t\tclass=\"telyrx-email-cta__input\"\n\t\t\t\t\tplaceholder=\"Enter your email\"\n\t\t\t\t\trequired\n\t\t\t\t\tautocomplete=\"email\"\n\t\t\t\t\/>\n\t\t\t\t<button type=\"submit\" class=\"telyrx-email-cta__button\">\n\t\t\t\t\tSubscribe\t\t\t\t<\/button>\n\t\t\t<\/div>\n\t\t\t<p class=\"telyrx-email-cta__status\" aria-live=\"polite\"><\/p>\n\t\t<\/form>\n\t\t<noscript>\n\t\t\t<p class=\"telyrx-email-cta__noscript\">Please enable JavaScript to use the signup form.<\/p>\n\t\t<\/noscript>\n\t<\/div>\n\n\n\n<section class=\"telyrx-side-effects\" data-toc-title=\"Side Effects\">\n\t<h2 class=\"telyrx-side-effects__heading\">Side Effects<\/h2>\n\t<hr class=\"telyrx-side-effects__separator\">\n\t<div class=\"telyrx-side-effects__content\">\n\t\t\n\n<p>PreviDent 5000 is generally safe, but some mild reactions in the mouth are possible.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-common-side-effects\">Common Side Effects<\/h3>\n\n\n\n<div class=\"telyrx-side-effects-chip telyrx-side-effects-chip--common\">\n\t\n\n<ul class=\"wp-block-list\">\n<li>Mild gum irritation<\/li>\n\n\n\n<li>A slight change in how things taste<\/li>\n\n\n\n<li>Temporary mouth soreness<\/li>\n<\/ul>\n\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-serious-side-effects\">Serious Side Effects<\/h3>\n\n\n\n<div class=\"telyrx-side-effects-chip telyrx-side-effects-chip--serious\">\n\t\n\n<p>Serious side effects are rare, but it&#8217;s important to know what to look for if they do occur. It\u2019s generally accepted that you stop taking the medication and immediately call the doctor if you experience any of the following symptoms:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Fluoride toxicity: <\/strong>This occurs if a large amount of paste is accidentally swallowed. Symptoms include nausea, stomach pain, or tremors.<\/li>\n\n\n\n<li><strong>Allergic reactions:<\/strong> It is generally advised to seek help if you notice swelling of the tongue or lips, or if you have trouble breathing.<\/li>\n<\/ul>\n\n<\/div>\n\n\n\n<p class=\"has-muted-color has-text-color\" style=\"font-size:0.875rem\"><em>Call your doctor immediately if you experience any concerning or prolonged symptoms.<\/em><\/p>\n\n\t<\/div>\n<\/section>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-pharmacist-tips\">Pharmacist Tips<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-spit-don-t-rinse\">Spit, Don&#8217;t Rinse<\/h3>\n\n\n\n<p>Do not rinse your mouth after brushing. Rinsing washes away the fluoride before it has a chance to soak into your teeth. Instead, thoroughly spit the toothpaste out but do not follow with water.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-wait-to-use-mouthwash\">Wait To Use Mouthwash<\/h3>\n\n\n\n<p>If you like using mouthwash, providers typically advise using it at a different time of day. Using it right after PreviDent will rinse the medicine away.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-be-patient-with-sensitivity\">Be Patient With Sensitivity<\/h3>\n\n\n\n<p>If you are using this for sensitive teeth, it may take 2 to 4 weeks of daily use before you feel a significant difference in sensitivity reduction.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-storage\">Storage<\/h3>\n\n\n\n<p>Standard guidelines usually recommend keeping the tube at room temperature and ensuring the cap is on tightly so the paste doesn&#8217;t dry out.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-drug-interactions\">Drug Interactions<\/h2>\n\n\n\n<p>While PreviDent 5000 is a topical treatment applied only to the teeth, it can still interact with certain substances or other fluoride treatments you may be using. Below are potential drug interactions for PreviDent 5000 toothpaste:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Calcium and dairy:<\/strong> Eating cheese or drinking milk immediately after brushing can reduce the effectiveness of fluoride. Waiting for at least 30 minutes after brushing before consuming dairy can help.<\/li>\n\n\n\n<li><strong>Other fluoride products:<\/strong> It is generally advised to tell your dentist if you are already taking fluoride drops or pills to make sure you aren&#8217;t getting too much.<\/li>\n<\/ul>\n\n\n\n<p>Always give your doctor and pharmacist a complete list of all your medications, vitamins, and supplements to check for potential interactions.<\/p>\n\n\n\n<section class=\"telyrx-faq-section\" data-toc-title=\"FAQs\">\n\t<h2 class=\"telyrx-faq-heading\">FAQs<\/h2>\n\t\t<div class=\"telyrx-faq-items\">\n\t\t\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Why is this toothpaste strictly prescription-only?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Because it contains five times as much fluoride as regular toothpaste, it is considered a medication. A healthcare provider needs to monitor toothpaste use to ensure it is necessary for your health and used safely.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Should I rinse my mouth out with water after brushing with PreviDent 5000 Booster Plus?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>No. It is generally advised that you should spit out the extra paste, but avoid rinsing with water for 30 minutes. Rinsing removes the fluoride that needs to sit on your enamel to strengthen it.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Do I use my regular toothpaste first and then this, or does this replace my normal toothpaste?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>No. PreviDent 5000 replaces your normal toothpaste. It is generally accepted that you only need to use one.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Can I use mouthwash right after I finish brushing with this?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Standard guidelines typically suggest waiting at least 30 minutes. If you use mouthwash immediately, it will wash away the concentrated fluoride.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Will using PreviDent 5000 reverse a cavity I already have?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>It can help address early signs of decay, such as white spots. However, if you already have a cavity in your tooth, the toothpaste cannot regrow the tooth. You will still need further dental care, such as a filling.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Can I use PreviDent 5000 Booster Plus in the morning?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Yes, it is generally accepted that you can use it in the morning and at night. However, the nighttime dose is the most important because your mouth is drier while you sleep, making your teeth more vulnerable.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Why did my dentist prescribe this after putting my braces or Invisalign attachments on?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Braces can trap food and bacteria against your teeth. PreviDent helps prevent permanent stains or cavities from forming around your brackets.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Can I eat a snack or drink a glass of water after using this?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>It is generally advised to wait at least 30 minutes. If you eat or drink too soon, the fluoride won&#8217;t have enough time to bond to your teeth.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Will this prescription toothpaste stop my tooth pain when I drink ice water?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>If you use the sensitive version, it contains medicine designed to block pain signals from cold or heat.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Can using prescription fluoride cause thyroid problems or other health issues?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>When used as directed (brushed on and spit out), there is no evidence that it causes systemic health problems. Most concerns about fluoride are related to drinking or swallowing large amounts over many years.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Can I use PreviDent 5000 Booster Plus if I have porcelain crowns, veneers, or bridges?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Yes. While it won&#8217;t change the porcelain, it protects the natural tooth structure where the crown meets your gum, which is a common spot for new cavities.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">How long will I have to use this toothpaste?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Some people use it only for a set time, such as while they have braces. Others with chronic dry mouth may use it permanently to maintain their dental health.<\/p>\n\n\t<\/div>\n<\/details>\n\n\t<\/div>\n<\/section>\n<script type=\"application\/ld+json\">{\"@context\":\"https:\/\/schema.org\",\"@type\":\"FAQPage\",\"mainEntity\":[{\"@type\":\"Question\",\"name\":\"Why is this toothpaste strictly prescription-only?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Because it contains five times as much fluoride as regular toothpaste, it is considered a medication. A healthcare provider needs to monitor toothpaste use to ensure it is necessary for your health and used safely.\"}},{\"@type\":\"Question\",\"name\":\"Should I rinse my mouth out with water after brushing with PreviDent 5000 Booster Plus?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"No. It is generally advised that you should spit out the extra paste, but avoid rinsing with water for 30 minutes. 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You will still need further dental care, such as a filling.\"}},{\"@type\":\"Question\",\"name\":\"Can I use PreviDent 5000 Booster Plus in the morning?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Yes, it is generally accepted that you can use it in the morning and at night. However, the nighttime dose is the most important because your mouth is drier while you sleep, making your teeth more vulnerable.\"}},{\"@type\":\"Question\",\"name\":\"Why did my dentist prescribe this after putting my braces or Invisalign attachments on?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Braces can trap food and bacteria against your teeth. PreviDent helps prevent permanent stains or cavities from forming around your brackets.\"}},{\"@type\":\"Question\",\"name\":\"Can I eat a snack or drink a glass of water after using this?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"It is generally advised to wait at least 30 minutes. If you eat or drink too soon, the fluoride won't have enough time to bond to your teeth.\"}},{\"@type\":\"Question\",\"name\":\"Will this prescription toothpaste stop my tooth pain when I drink ice water?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"If you use the sensitive version, it contains medicine designed to block pain signals from cold or heat.\"}},{\"@type\":\"Question\",\"name\":\"Can using prescription fluoride cause thyroid problems or other health issues?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"When used as directed (brushed on and spit out), there is no evidence that it causes systemic health problems. Most concerns about fluoride are related to drinking or swallowing large amounts over many years.\"}},{\"@type\":\"Question\",\"name\":\"Can I use PreviDent 5000 Booster Plus if I have porcelain crowns, veneers, or bridges?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Yes. While it won't change the porcelain, it protects the natural tooth structure where the crown meets your gum, which is a common spot for new cavities.\"}},{\"@type\":\"Question\",\"name\":\"How long will I have to use this toothpaste?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Some people use it only for a set time, such as while they have braces. Others with chronic dry mouth may use it permanently to maintain their dental health.\"}}]}<\/script>\n\n<div class=\"telyrx-comparable-medications wp-block-telyrx-comparable-medications\">\n\t<h2 class=\"telyrx-comparable-medications__title\">Comparable Medications<\/h2>\n\t\t\t<div class=\"telyrx-comparable-medications__intro\">\n\n<p><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong>Regular Colgate, Clinpro 5000, or Gel-Kam?<\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/p>\n\n\n\n<p>Your doctor may recommend an alternative to PreviDent 5000 toothpaste if there are concerns about drug interactions.<\/p>\n\n\n\n<p>Possible alternatives to PreviDent include:<\/p>\n\n<\/div>\n\t\t\t\t<div class=\"telyrx-comparable-medications__item\">\n\t\t\t<div class=\"telyrx-comparable-medications__item-top\">\n\t\t\t\t<div class=\"telyrx-comparable-medications__item-info\">\n\t\t\t\t\t<h3 class=\"telyrx-comparable-medications__name\">\n\t\t\t\t\t\t\t\t\t\t\t\t\tRegular Colgate\t\t\t\t\t\t\t\t\t\t\t<\/h3>\n\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<p class=\"telyrx-comparable-medications__description\">\n\t\t\t\t\tStandard toothpastes can help with daily cleaning but contain a smaller amount of sodium fluoride (about 0.24%). PreviDent 5000 contains 1.1% sodium fluoride, making it stronger for people prone to cavities.\t\t\t\t<\/p>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<hr class=\"telyrx-comparable-medications__divider\">\n\t\t\t\t\t<div class=\"telyrx-comparable-medications__item\">\n\t\t\t<div class=\"telyrx-comparable-medications__item-top\">\n\t\t\t\t<div class=\"telyrx-comparable-medications__item-info\">\n\t\t\t\t\t<h3 class=\"telyrx-comparable-medications__name\">\n\t\t\t\t\t\t\t\t\t\t\t\t\tClinpro 5000\t\t\t\t\t\t\t\t\t\t\t<\/h3>\n\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<p class=\"telyrx-comparable-medications__description\">\n\t\t\t\t\tThis is another prescription toothpaste similar to PreviDent. Both have the same amount of fluoride. Some people prefer the taste or feel of one over the other, but they both offer similar protection.\t\t\t\t<\/p>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<hr class=\"telyrx-comparable-medications__divider\">\n\t\t\t\t\t<div class=\"telyrx-comparable-medications__item\">\n\t\t\t<div class=\"telyrx-comparable-medications__item-top\">\n\t\t\t\t<div class=\"telyrx-comparable-medications__item-info\">\n\t\t\t\t\t<h3 class=\"telyrx-comparable-medications__name\">\n\t\t\t\t\t\t\t\t\t\t\t\t\tGel-Kam\t\t\t\t\t\t\t\t\t\t\t<\/h3>\n\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<p class=\"telyrx-comparable-medications__description\">\n\t\t\t\t\tThis over-the-counter gel helps with sensitivity and gum health. It has less fluoride than PreviDent 5000 and is usually used as a supplement rather than a replacement for your toothpaste.\t\t\t\t<\/p>\n\t\t\t\t\t<\/div>\n\n\t\t\t<\/div>\n\n\n<div class=\"telyrx-product-list telyrx-product-list--single wp-block-telyrx-product-list\">\n\t\t\t\t\t<a class=\"telyrx-product-list__card telyrx-product-list__card--single\" href=\"https:\/\/telyrx.com\/medications\/colgate-prevident-5000-plus-cream\">\n\t\t\t\t\t\t\t<img\n\t\t\t\t\tclass=\"telyrx-product-list__image\"\n\t\t\t\t\tsrc=\"https:\/\/telyrx.com\/media\/catalog\/product\/c\/o\/colgate_prevident_pluse_cream.png\"\n\t\t\t\t\talt=\"Colgate PreviDent 5000 Plus Cream\"\n\t\t\t\t\twidth=\"213\"\n\t\t\t\t\theight=\"213\"\n\t\t\t\t\tloading=\"lazy\"\n\t\t\t\t>\n\t\t\t\t\t\t<div class=\"telyrx-product-list__content\">\n\t\t\t\t<p class=\"telyrx-product-list__name\">Colgate PreviDent 5000 Plus Cream<\/p>\n\t\t\t\t<span class=\"telyrx-product-list__cta telyrx-product-list__cta--yellow\">\n\t\t\t\t\tView Product\t\t\t\t<\/span>\n\t\t\t<\/div>\n\t\t<\/a>\n\t<\/div>\n\n\n<div class=\"telyrx-product-list-section alignfull wp-block-telyrx-product-list\">\n\t<h2 class=\"telyrx-product-list-section__heading\" data-toc-hidden=\"true\">We Have PreviDent 5000 Toothpaste in Stock. Get Yours Today!<\/h2>\n\t<div class=\"telyrx-product-list telyrx-product-list--footer-multi\">\n\t\t<div class=\"telyrx-product-list__grid\">\n\t\t\t\t\t\t\t<a class=\"telyrx-product-list__card\" href=\"https:\/\/telyrx.com\/medications\/colgate-prevident-5000-plus-cream\">\n\t\t\t\t\t\t\t\t\t\t\t<img\n\t\t\t\t\t\t\tclass=\"telyrx-product-list__image\"\n\t\t\t\t\t\t\tsrc=\"https:\/\/telyrx.com\/media\/catalog\/product\/c\/o\/colgate_prevident_pluse_cream.png\"\n\t\t\t\t\t\t\talt=\"Colgate PreviDent 5000 Plus Cream\"\n\t\t\t\t\t\t\twidth=\"213\"\n\t\t\t\t\t\t\theight=\"213\"\n\t\t\t\t\t\t\tloading=\"lazy\"\n\t\t\t\t\t\t>\n\t\t\t\t\t\t\t\t\t\t<div class=\"telyrx-product-list__content\">\n\t\t\t\t\t\t<p class=\"telyrx-product-list__name\">Colgate PreviDent 5000 Plus Cream<\/p>\n\t\t\t\t\t\t<span class=\"telyrx-product-list__cta telyrx-product-list__cta--yellow\">\n\t\t\t\t\t\t\tOrder Now\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/a>\n\t\t\t\t\t<\/div>\n\t<\/div>\n\t\t\t<div class=\"telyrx-product-list-section__extra\">\n\t\t\t<p class=\"has-muted-color has-text-color has-urbanist-font-family\" style=\"font-size:0.875rem;font-style:italic;font-weight:400;line-height:1.571\"><strong>Important:<\/strong> Information on this page is for educational purposes only. Prescribing decisions are made by independent, licensed providers. TelyRx operates technology-enabled pharmacies and a telehealth platform that connects patients with licensed providers. Prescriptions, when provider-approved and issued, are filled and shipped by TelyRx-affiliated pharmacies. We do not employ physicians or make prescribing decisions. Learn more about our editorial standards <a href=\"\/blog\/editorial-standards\/\">here<\/a>.<\/p>\t\t<\/div>\n\t<\/div>\n","protected":false},"excerpt":{"rendered":"<p>PreviDent 5000, a brand name product with the active ingredient sodium fluoride, is a prescription-only fluoride toothpaste used to prevent dental caries (cavities) and manage tooth hypersensitivity. <\/p>\n<p>It contains 1.1% sodium fluoride, which equates to 5,000 parts per million (ppm) of fluoride, about four to five times the amount found in standard over-the-counter (OTC) toothpastes.<\/p>\n","protected":false},"author":2,"featured_media":8368,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"single-medication","format":"standard","meta":{"content-type":"","telyrx_subtitle":"Uses, Side Effects, Dosage & FAQs (2026 Guide)","telyrx_last_updated":"2026-05-08T12:13","telyrx_reviewer_name":"Ashley Robinson","telyrx_reviewer_credentials":"PharmD","telyrx_reviewer_job_title":"Pharmacy Manager","telyrx_reviewer_affiliation":"TelyRx","telyrx_reviewer_url":"","telyrx_show_reviewer_job_title":"0","telyrx_show_reviewer_affiliation":"0","telyrx_show_toc":"1","telyrx_reviewer_bio":"","telyrx_reviewer_avatar":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","_telyrx_clean_url":"\/medications\/colgate-prevident-5000-plus-cream\/what-is\/"},"categories":[86],"tags":[],"class_list":["post-8360","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medications"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.6 (Yoast SEO v27.6) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>What Is PreviDent 5000 Toothpaste? Uses, Side Effects, Dosage, and FAQs<\/title>\n<meta name=\"description\" content=\"Learn what PreviDent 5000 Toothpaste is, how it works, common side effects, and how to get it prescribed online through TelyRx.com\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/telyrx.com\/blog\/medications\/what-is-prevident-5000-toothpaste\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"What Is PreviDent 5000 Toothpaste?\" \/>\n<meta property=\"og:description\" content=\"Learn what PreviDent 5000 Toothpaste is, how it works, common side effects, and how to get it prescribed online through TelyRx.com\" \/>\n<meta property=\"og:url\" content=\"https:\/\/telyrx.com\/blog\/medications\/what-is-prevident-5000-toothpaste\/\" \/>\n<meta property=\"og:site_name\" content=\"TelyRx Blog\" \/>\n<meta property=\"article:published_time\" content=\"2026-05-08T12:13:53+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-05-08T12:14:09+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/telyrx.com\/blog\/wp-content\/uploads\/2026\/05\/colgate_prevident_pluse_cream.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"900\" \/>\n\t<meta property=\"og:image:height\" content=\"900\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Mariah Powers\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Mariah Powers\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/medications\\\/what-is-prevident-5000-toothpaste\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/medications\\\/what-is-prevident-5000-toothpaste\\\/\"},\"author\":{\"name\":\"Mariah Powers\",\"@id\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/#\\\/schema\\\/person\\\/f1042a29c24ab7dd3c5f0fff9a06746b\"},\"headline\":\"What Is PreviDent 5000 Toothpaste?\",\"datePublished\":\"2026-05-08T12:13:53+00:00\",\"dateModified\":\"2026-05-08T12:13:53+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/medications\\\/what-is-prevident-5000-toothpaste\\\/\"},\"wordCount\":1266,\"publisher\":{\"@id\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/medications\\\/what-is-prevident-5000-toothpaste\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/wp-content\\\/uploads\\\/2026\\\/05\\\/colgate_prevident_pluse_cream.jpg\",\"articleSection\":[\"Medications\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/medications\\\/what-is-prevident-5000-toothpaste\\\/\",\"url\":\"https:\\\/\\\/telyrx.com\\\/blog\\\/medications\\\/what-is-prevident-5000-toothpaste\\\/\",\"name\":\"What Is PreviDent 5000 Toothpaste? 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