{"id":8170,"date":"2026-04-27T18:00:34","date_gmt":"2026-04-27T18:00:34","guid":{"rendered":"https:\/\/telyrx.com\/blog\/?p=8170"},"modified":"2026-04-27T18:00:48","modified_gmt":"2026-04-27T18:00:48","slug":"what-is-selenium-sulfide-shampoo","status":"publish","type":"post","link":"https:\/\/telyrx.com\/blog\/medications\/what-is-selenium-sulfide-shampoo\/","title":{"rendered":"What Is Selenium Sulfide Shampoo?"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\" id=\"h-how-it-works\">How It Works<\/h2>\n\n\n\n<p>Selenium sulfide works by:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Reducing the production of natural oils on the scalp<\/li>\n\n\n\n<li>Slowing down the growth and shedding of skin cells on the skin&#8217;s surface and within the hair follicles<\/li>\n\n\n\n<li>Killing the yeast and fungus associated with skin irritation and flaking<\/li>\n<\/ul>\n\n\n\n<div class=\"quick-facts-card\">\n  <table class=\"quick-facts-table\">\n    <colgroup>\n      <col\/>\n      <col\/>\n    <\/colgroup>\n\n    <thead>\n      <tr>\n        <th colspan=\"2\">Quick Facts<\/th>\n      <\/tr>\n    <\/thead>\n\n    <tbody>\n      <tr>\n        <td><strong>Common Brands<\/strong><\/td>\n        <td>Selsun Blue 2-in-1, Selsun Blue Medicated, Selsun Blue Moisturizing, Selsun Blue Normal to Oily<\/td>\n      <\/tr>\n\n      <tr>\n         <td><strong>Drug Class<\/strong><\/td>\n        <td>Topical anti-infective<\/td>\n      <\/tr>\n\n      <tr>\n        <td><strong>Generic Status<\/strong><\/td>\n        <td>Generic is available<\/td>\n      <\/tr>\n\n      <tr>\n         <td><strong>Availability<\/strong><\/td>\n        <td>Prescription-strength and over-the-counter<\/td>\n    <\/tbody>\n  <\/table>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-dosing\">Dosing<\/h2>\n\n\n\n<p>Selenium sulfide shampoo is available in the following prescription-strength formulations:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>2.25% shampoo<\/li>\n\n\n\n<li>2.3% shampoo<\/li>\n<\/ul>\n\n\n\n<p>Dosing depends on the specific condition being treated:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Dandruff and seborrheic dermatitis of the scalp: <\/strong>Shake the bottle well and wet the hair or skin. Apply onto the scalp and work into a full lather. Rinse thoroughly. Repeat twice a week for 2 weeks and then less frequently as recommended by your provider.\u00a0<\/li>\n\n\n\n<li><strong>Tinea versicolor: <\/strong>Shake the bottle well and wet the skin. Apply onto the affected areas and work into a full lather. Leave on for 10 minutes and then rinse off thoroughly. Repeat daily for 7 days.<\/li>\n<\/ul>\n\n\n\n<p><em><strong>Note:<\/strong> Dosing information below is educational only. Your prescribing physician will determine your specific dose based on your individual health needs. Always follow your healthcare provider\u2019s instructions for exact dosing.<\/em><\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-uses\">Uses<\/h2>\n\n\n\n<p><strong>FDA-Approved Uses<\/strong><\/p>\n\n\n\n<p>Selenium sulfide shampoo is FDA-approved to treat:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Dandruff<\/li>\n\n\n\n<li>Seborrheic dermatitis of the scalp, a condition that causes itchy, flaky, and dry skin<\/li>\n\n\n\n<li>Tinea versicolor, a fungal skin infection that causes discolored patches on the skin<\/li>\n<\/ul>\n\n\n\n<p><strong>Off-Label Uses<\/strong><\/p>\n\n\n\n<p>You may see selenium sulfide shampoo prescribed for uses that are not &#8220;FDA-approved.&#8221; This is a very common and legal practice called &#8220;off-label&#8221; prescribing, where a doctor uses their clinical judgment to prescribe a drug for a different (but well-researched) purpose.<\/p>\n\n\n\n<p>There are currently no common off-label uses for selenium sulfide shampoo.<\/p>\n\n\n<div class=\"telyrx-email-cta alignfull wp-block-telyrx-email-signup\">\n\t<h2 class=\"telyrx-email-cta__heading\" data-toc-hidden=\"true\">Get Savings Updates<\/h2>\n\t<p class=\"telyrx-email-cta__description\">Join our mailing list for exclusive deals and more.<\/p>\n\t\t\t<form\n\t\t\tid=\"telyrx-email-form-1\"\n\t\t\tclass=\"telyrx-email-cta__form\"\n\t\t\tdata-portal-id=\"46401311\"\n\t\t\tdata-form-id=\"14e1d7d5-6b17-4228-b42e-c06d1a6c240b\"\n\t\t\tdata-i18n=\"{&quot;subscribe&quot;:&quot;Subscribe&quot;,&quot;success&quot;:&quot;Thanks! You&#039;re subscribed.&quot;,&quot;error&quot;:&quot;Something went wrong. Please try again.&quot;}\"\n\t\t>\n\t\t\t<div class=\"telyrx-email-cta__pill\">\n\t\t\t\t<input\n\t\t\t\t\ttype=\"email\"\n\t\t\t\t\tname=\"email\"\n\t\t\t\t\tclass=\"telyrx-email-cta__input\"\n\t\t\t\t\tplaceholder=\"Enter your email\"\n\t\t\t\t\trequired\n\t\t\t\t\tautocomplete=\"email\"\n\t\t\t\t\/>\n\t\t\t\t<button type=\"submit\" class=\"telyrx-email-cta__button\">\n\t\t\t\t\tSubscribe\t\t\t\t<\/button>\n\t\t\t<\/div>\n\t\t\t<p class=\"telyrx-email-cta__status\" aria-live=\"polite\"><\/p>\n\t\t<\/form>\n\t\t<noscript>\n\t\t\t<p class=\"telyrx-email-cta__noscript\">Please enable JavaScript to use the signup form.<\/p>\n\t\t<\/noscript>\n\t<\/div>\n\n\n\n<section class=\"telyrx-side-effects\" data-toc-title=\"Side Effects\">\n\t<h2 class=\"telyrx-side-effects__heading\">Side Effects<\/h2>\n\t<hr class=\"telyrx-side-effects__separator\">\n\t<div class=\"telyrx-side-effects__content\">\n\t\t\n\n<p>Like all medications, selenium sulfide shampoo can cause side effects. Some common side effects may improve over time as your body adjusts to the medication. Other side effects may be serious and require medical attention.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-common-side-effects\">Common Side Effects<\/h3>\n\n\n\n<div class=\"telyrx-side-effects-chip telyrx-side-effects-chip--common\">\n\t\n\n<ul class=\"wp-block-list\">\n<li>Hair discoloration<\/li>\n\n\n\n<li>Oiliness or dryness of hair and scalp<\/li>\n\n\n\n<li>Skin irritation or itchiness<\/li>\n\n\n\n<li>Increase in normal hair loss<\/li>\n<\/ul>\n\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-serious-side-effects\">Serious Side Effects<\/h3>\n\n\n\n<div class=\"telyrx-side-effects-chip telyrx-side-effects-chip--serious\">\n\t\n\n<p>Serious side effects are rare, but it&#8217;s important to know what to look for if they do occur. Stop using selenium sulfide shampoo and call your doctor immediately if you experience:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Severe allergic reactions:<\/strong> Symptoms include swelling of the face, lips, tongue, or throat; difficulty breathing or swallowing; racing heart; severe rash or itching; fever.\u00a0<\/li>\n\n\n\n<li><strong>Severe skin reactions: <\/strong>Selenium sulfide shampoo can cause mild skin irritation, but for some people, reactions may be more severe. If you experience skin burning, itching, crusting, or peeling, your doctor may recommend a different medication.<\/li>\n<\/ul>\n\n<\/div>\n\n\n\n<p class=\"has-muted-color has-text-color\" style=\"font-size:0.875rem\"><em>Call your doctor immediately if you experience any concerning or prolonged symptoms.<\/em><\/p>\n\n\t<\/div>\n<\/section>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-pharmacist-tips\">Pharmacist Tips<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-shake-the-bottle-well\">Shake The Bottle Well<\/h3>\n\n\n\n<p>Doing so before every application helps ensure the medication is properly mixed.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-remove-jewelry-when-applying\">Remove Jewelry When Applying<\/h3>\n\n\n\n<p>Providers typically recommend removing all jewelry before applying selenium sulfide, as the medication can damage it.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-rinse-thoroughly\">Rinse Thoroughly<\/h3>\n\n\n\n<p>To help prevent hair discoloration, standard guidelines recommend thoroughly rinsing your hair and scalp after each application.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-avoid-sensitive-areas\">Avoid Sensitive Areas<\/h3>\n\n\n\n<p>This medication is for external use only. Avoid getting it into your nose, mouth, genitals, or eyes. If it accidentally gets into your eyes, rinse them thoroughly with cool tap water.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-do-not-apply-to-broken-skin\">Do Not Apply To Broken Skin<\/h3>\n\n\n\n<p>Do not apply selenium sulfide shampoo to skin that is inflamed, red, swollen, or injured, as this can cause severe irritation.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-wash-your-hands\">Wash Your Hands<\/h3>\n\n\n\n<p>Always wash your hands immediately before and after using the medication.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-be-aware-that-the-shampoo-may-change-color\">Be Aware That The Shampoo May Change Color<\/h3>\n\n\n\n<p>It is normal for some selenium sulfide shampoos to darken over time. As long as they aren\u2019t expired, they are still safe to use.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-store-at-room-temperature\">Store At Room Temperature<\/h3>\n\n\n\n<p>Selenium sulfide shampoo should be stored at 68\u00b0F to 77\u00b0F (20\u00b0C to 25\u00b0C) in a cool, dry place away from light.\u00a0<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-tell-your-provider-if-you-re-pregnant-or-breastfeeding\">Tell Your Provider If You\u2019re Pregnant Or Breastfeeding<\/h3>\n\n\n\n<p>It is not known if selenium sulfide can affect pregnancy or pass into breast milk. Tell your healthcare provider if you are pregnant, breastfeeding, or planning to be pregnant so they can advise whether this medication is safe for you to use.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-drug-interactions\">Drug Interactions<\/h2>\n\n\n\n<p>Certain medications and substances can interact with selenium sulfide shampoo, potentially altering its effectiveness or increasing the risk of side effects. For example, other skin products can affect the shampoo. It\u2019s recommended to avoid using other skin products on the affected area unless your provider says it\u2019s okay.<\/p>\n\n\n\n<p>Always give your doctor and pharmacist a complete list of all your medications, vitamins, and supplements to check for potential interactions.<\/p>\n\n\n\n<section class=\"telyrx-faq-section\" data-toc-title=\"FAQs\">\n\t<h2 class=\"telyrx-faq-heading\">FAQs<\/h2>\n\t\t<div class=\"telyrx-faq-items\">\n\t\t\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Why does this shampoo smell like rotten eggs?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Selenium sulfide shampoo can be smelly because it contains sulfur.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">How long must the selenium sulfide shampoo sit before I can wash it off?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>It depends on the condition you are treating. For seborrheic dermatitis and dandruff, standard guidelines recommend lathering the shampoo and then rinsing. For the fungal infection tinea versicolor, it is recommended to leave the medication on for 10 minutes before washing it off thoroughly.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">What is the difference between the prescription 2.25% bottle and the regular Selsun Blue at the store?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Prescription-strength selenium sulfide contains a higher concentration (such as 2.25% or 2.3%) compared to the 1% concentration found in over-the-counter selenium sulfide shampoo. Prescription-strength selenium sulfide can also treat tinea versicolor in addition to dandruff and seborrheic dermatitis, whereas over-the-counter versions are generally only used for dandruff and seborrheic dermatitis.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Can I use my regular conditioner after washing with this?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Providers typically recommend consulting your dermatologist about hair care during treatment, especially since selenium sulfide shampoo can make your hair feel dry.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Will using selenium sulfide shampoo actually cure my skin fungus, or just my dandruff?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Prescription-strength selenium sulfide shampoo is an antifungal medication that treats tinea versicolor while also managing dandruff and seborrheic dermatitis.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Can I use this shampoo to get rid of \u201cfungal acne\u201d?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Selenium sulfide shampoo is FDA-approved to treat tinea versicolor, dandruff, and seborrheic dermatitis. Healthcare providers may determine it is appropriate to prescribe selenium sulfide for other conditions based on their clinical judgment. It\u2019s best to check with your dermatologist before applying it to your face for fungal acne.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Am I supposed to use selenium sulfide shampoo every single day?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Usually, no. For dandruff and seborrheic dermatitis, providers typically recommend avoiding daily use to reduce the risk of dryness and irritation. It\u2019s generally used twice a week to manage symptoms. However, if you are treating tinea versicolor, a dermatologist may instruct you to use it daily for a short duration, such as 7 days.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Is it normal for my scalp to burn slightly, or feel incredibly dry after rinsing this out?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Mild skin irritation and unusual dryness are some of the most common side effects of this medication. However, if the burning is severe or your skin begins to crust or peel, it is important to report this to your care team as soon as possible.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Does using selenium sulfide make your hair thin out or fall out?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Yes, it is possible. People have reported experiencing a greater-than-normal amount of hair loss after using selenium sulfide. If you are concerned about hair thinning, talk to your healthcare provider.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">How many washes does it usually take for itching to stop?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>It may take 1\u20132 weeks, depending on the condition you\u2019re treating. When used for dandruff or seborrheic dermatitis, selenium sulfide shampoo should be used twice a week for the first 2 weeks to control symptoms. Tinea versicolor is typically treated with a week of daily applications.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Is it safe to use this medicated shampoo if I am pregnant or breastfeeding?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>It is not recommended to use selenium sulfide during pregnancy because it is unknown if it can harm an unborn baby. It is also unknown if the medication passes into breast milk. Providers typically recommend speaking with your healthcare team to discuss the safest options during pregnancy and breastfeeding.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Will selenium sulfide shampoo cure regular dry scalp from winter weather?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Selenium sulfide is a medicated shampoo used to reduce the natural oil production on the scalp and slow the growth of yeast that causes dandruff, seborrheic dermatitis, and fungal infections. It is not generally used for winter dryness.<\/p>\n\n\t<\/div>\n<\/details>\n\n\t<\/div>\n<\/section>\n<script type=\"application\/ld+json\">{\"@context\":\"https:\/\/schema.org\",\"@type\":\"FAQPage\",\"mainEntity\":[{\"@type\":\"Question\",\"name\":\"Why does this shampoo smell like rotten eggs?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Selenium sulfide shampoo can be smelly because it contains sulfur.\"}},{\"@type\":\"Question\",\"name\":\"How long must the selenium sulfide shampoo sit before I can wash it off?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"It depends on the condition you are treating. For seborrheic dermatitis and dandruff, standard guidelines recommend lathering the shampoo and then rinsing. For the fungal infection tinea versicolor, it is recommended to leave the medication on for 10 minutes before washing it off thoroughly.\"}},{\"@type\":\"Question\",\"name\":\"What is the difference between the prescription 2.25% bottle and the regular Selsun Blue at the store?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Prescription-strength selenium sulfide contains a higher concentration (such as 2.25% or 2.3%) compared to the 1% concentration found in over-the-counter selenium sulfide shampoo. Prescription-strength selenium sulfide can also treat tinea versicolor in addition to dandruff and seborrheic dermatitis, whereas over-the-counter versions are generally only used for dandruff and seborrheic dermatitis.\"}},{\"@type\":\"Question\",\"name\":\"Can I use my regular conditioner after washing with this?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Providers typically recommend consulting your dermatologist about hair care during treatment, especially since selenium sulfide shampoo can make your hair feel dry.\"}},{\"@type\":\"Question\",\"name\":\"Will using selenium sulfide shampoo actually cure my skin fungus, or just my dandruff?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Prescription-strength selenium sulfide shampoo is an antifungal medication that treats tinea versicolor while also managing dandruff and seborrheic dermatitis.\"}},{\"@type\":\"Question\",\"name\":\"Can I use this shampoo to get rid of \u201cfungal acne\u201d?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Selenium sulfide shampoo is FDA-approved to treat tinea versicolor, dandruff, and seborrheic dermatitis. Healthcare providers may determine it is appropriate to prescribe selenium sulfide for other conditions based on their clinical judgment. It\u2019s best to check with your dermatologist before applying it to your face for fungal acne.\"}},{\"@type\":\"Question\",\"name\":\"Am I supposed to use selenium sulfide shampoo every single day?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Usually, no. For dandruff and seborrheic dermatitis, providers typically recommend avoiding daily use to reduce the risk of dryness and irritation. It\u2019s generally used twice a week to manage symptoms. However, if you are treating tinea versicolor, a dermatologist may instruct you to use it daily for a short duration, such as 7 days.\"}},{\"@type\":\"Question\",\"name\":\"Is it normal for my scalp to burn slightly, or feel incredibly dry after rinsing this out?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Mild skin irritation and unusual dryness are some of the most common side effects of this medication. However, if the burning is severe or your skin begins to crust or peel, it is important to report this to your care team as soon as possible.\"}},{\"@type\":\"Question\",\"name\":\"Does using selenium sulfide make your hair thin out or fall out?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Yes, it is possible. People have reported experiencing a greater-than-normal amount of hair loss after using selenium sulfide. If you are concerned about hair thinning, talk to your healthcare provider.\"}},{\"@type\":\"Question\",\"name\":\"How many washes does it usually take for itching to stop?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"It may take 1\u20132 weeks, depending on the condition you\u2019re treating. When used for dandruff or seborrheic dermatitis, selenium sulfide shampoo should be used twice a week for the first 2 weeks to control symptoms. Tinea versicolor is typically treated with a week of daily applications.\"}},{\"@type\":\"Question\",\"name\":\"Is it safe to use this medicated shampoo if I am pregnant or breastfeeding?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"It is not recommended to use selenium sulfide during pregnancy because it is unknown if it can harm an unborn baby. It is also unknown if the medication passes into breast milk. Providers typically recommend speaking with your healthcare team to discuss the safest options during pregnancy and breastfeeding.\"}},{\"@type\":\"Question\",\"name\":\"Will selenium sulfide shampoo cure regular dry scalp from winter weather?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Selenium sulfide is a medicated shampoo used to reduce the natural oil production on the scalp and slow the growth of yeast that causes dandruff, seborrheic dermatitis, and fungal infections. It is not generally used for winter dryness.\"}}]}<\/script>\n\n<div class=\"telyrx-comparable-medications wp-block-telyrx-comparable-medications\">\n\t<h2 class=\"telyrx-comparable-medications__title\">Comparable Medications<\/h2>\n\t\t\t<div class=\"telyrx-comparable-medications__intro\">\n\n<p><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong>Selenium sulfide shampoo, Nizoral (ketoconazole 1% or 2%), Neutrogena T\/Sal (salicylic acid), or clobetasol shampoo (Clobex)?<\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/p>\n\n\n\n<p>There are several medications your doctor can prescribe instead of selenium sulfide shampoo. Here are a few possible alternatives below.<\/p>\n\n<\/div>\n\t\t\t\t<div class=\"telyrx-comparable-medications__item\">\n\t\t\t<div class=\"telyrx-comparable-medications__item-top\">\n\t\t\t\t<div class=\"telyrx-comparable-medications__item-info\">\n\t\t\t\t\t<h3 class=\"telyrx-comparable-medications__name\">\n\t\t\t\t\t\t\t\t\t\t\t\t\tNizoral\t\t\t\t\t\t\t\t\t\t\t<\/h3>\n\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<p class=\"telyrx-comparable-medications__description\">\n\t\t\t\t\tAn over-the-counter (1%) or prescription (2%) antifungal medication used to treat dandruff and tinea versicolor.\t\t\t\t<\/p>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<hr class=\"telyrx-comparable-medications__divider\">\n\t\t\t\t\t<div class=\"telyrx-comparable-medications__item\">\n\t\t\t<div class=\"telyrx-comparable-medications__item-top\">\n\t\t\t\t<div class=\"telyrx-comparable-medications__item-info\">\n\t\t\t\t\t<h3 class=\"telyrx-comparable-medications__name\">\n\t\t\t\t\t\t\t\t\t\t\t\t\tNeutrogena T\/Sal \t\t\t\t\t\t\t\t\t\t\t<\/h3>\n\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<p class=\"telyrx-comparable-medications__description\">\n\t\t\t\t\tAn over-the-counter shampoo used to treat dandruff, seborrheic dermatitis, psoriasis, acne, eczema, and other conditions.\t\t\t\t<\/p>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<hr class=\"telyrx-comparable-medications__divider\">\n\t\t\t\t\t<div class=\"telyrx-comparable-medications__item\">\n\t\t\t<div class=\"telyrx-comparable-medications__item-top\">\n\t\t\t\t<div class=\"telyrx-comparable-medications__item-info\">\n\t\t\t\t\t<h3 class=\"telyrx-comparable-medications__name\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"telyrx-comparable-medications__name-link\" href=\"https:\/\/telyrx.com\/clobetasol-shampoo\">\n\t\t\t\t\t\t\t\tClobetasol Shampoo\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/h3>\n\n\t\t\t\t\t\t\t\t\t\t\t<p class=\"telyrx-comparable-medications__price\">\n\t\t\t\t\t\t\tFrom $69.98\t\t\t\t\t\t<\/p>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<a class=\"telyrx-comparable-medications__cta\" href=\"https:\/\/telyrx.com\/clobetasol-shampoo\">\n\t\t\t\t\t\tView Product\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<p class=\"telyrx-comparable-medications__description\">\n\t\t\t\t\tA prescription topical corticosteroid used to treat moderate to severe scalp psoriasis.\t\t\t\t<\/p>\n\t\t\t\t\t<\/div>\n\n\t\t\t<\/div>\n\n\n<div class=\"telyrx-product-list telyrx-product-list--single wp-block-telyrx-product-list\">\n\t\t\t\t\t<a class=\"telyrx-product-list__card telyrx-product-list__card--single\" href=\"https:\/\/telyrx.com\/medications\/selenium-sulfide-shampoo\">\n\t\t\t\t\t\t\t<img\n\t\t\t\t\tclass=\"telyrx-product-list__image\"\n\t\t\t\t\tsrc=\"https:\/\/telyrx.com\/media\/catalog\/product\/s\/e\/selenium_sulfide_shampoo_2.25percent_shampoo_180ml_1_bottle_1907_001_sq-bg_ai_gen_2_4.png\"\n\t\t\t\t\talt=\"Selenium Sulfide Shampoo\"\n\t\t\t\t\twidth=\"213\"\n\t\t\t\t\theight=\"213\"\n\t\t\t\t\tloading=\"lazy\"\n\t\t\t\t>\n\t\t\t\t\t\t<div class=\"telyrx-product-list__content\">\n\t\t\t\t<p class=\"telyrx-product-list__name\">Selenium Sulfide Shampoo<\/p>\n\t\t\t\t<span class=\"telyrx-product-list__cta telyrx-product-list__cta--yellow\">\n\t\t\t\t\tView Product\t\t\t\t<\/span>\n\t\t\t<\/div>\n\t\t<\/a>\n\t<\/div>\n\n\n<div class=\"telyrx-product-list-section alignfull wp-block-telyrx-product-list\">\n\t<h2 class=\"telyrx-product-list-section__heading\" data-toc-hidden=\"true\">We Have Selenium Sulfide Shampoo in Stock. Get Yours Today!<\/h2>\n\t<div class=\"telyrx-product-list telyrx-product-list--footer-multi\">\n\t\t<div class=\"telyrx-product-list__grid\">\n\t\t\t\t\t\t\t<a class=\"telyrx-product-list__card\" href=\"https:\/\/telyrx.com\/medications\/selenium-sulfide-shampoo\">\n\t\t\t\t\t\t\t\t\t\t\t<img\n\t\t\t\t\t\t\tclass=\"telyrx-product-list__image\"\n\t\t\t\t\t\t\tsrc=\"https:\/\/telyrx.com\/media\/catalog\/product\/s\/e\/selenium_sulfide_shampoo_2.25percent_shampoo_180ml_1_bottle_1907_001_sq-bg_ai_gen_2_4.png\"\n\t\t\t\t\t\t\talt=\"Selenium Sulfide Shampoo\"\n\t\t\t\t\t\t\twidth=\"213\"\n\t\t\t\t\t\t\theight=\"213\"\n\t\t\t\t\t\t\tloading=\"lazy\"\n\t\t\t\t\t\t>\n\t\t\t\t\t\t\t\t\t\t<div class=\"telyrx-product-list__content\">\n\t\t\t\t\t\t<p class=\"telyrx-product-list__name\">Selenium Sulfide Shampoo<\/p>\n\t\t\t\t\t\t<span class=\"telyrx-product-list__cta telyrx-product-list__cta--yellow\">\n\t\t\t\t\t\t\tOrder Now\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/a>\n\t\t\t\t\t<\/div>\n\t<\/div>\n\t\t\t<div class=\"telyrx-product-list-section__extra\">\n\t\t\t<p class=\"has-muted-color has-text-color has-urbanist-font-family\" style=\"font-size:0.875rem;font-style:italic;font-weight:400;line-height:1.571\"><strong>Important:<\/strong> Information on this page is for educational purposes only. Prescribing decisions are made by independent, licensed providers. TelyRx operates technology-enabled pharmacies and a telehealth platform that connects patients with board-certified licensed providers. Prescriptions, when provider-approved and issued, are filled and shipped by TelyRx-affiliated pharmacies. We do not employ physicians or make prescribing decisions. Learn more about our editorial standards <a href=\"\/blog\/editorial-standards\/\">here<\/a>.<\/p>\t\t<\/div>\n\t<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Selenium sulfide shampoo (brand name Selsun Blue) is a prescription and over-the-counter (OTC) topical medication. It\u2019s primarily used to treat the flaking and itching associated with dandruff and seborrheic dermatitis. It\u2019s also used to treat tinea versicolor, a fungal infection that causes discolored patches on the skin. <\/p>\n<p>Common side effects of selenium sulfide shampoo include skin irritation or itchiness, oily or dry hair and scalp, and hair discoloration.<\/p>\n","protected":false},"author":2,"featured_media":8171,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"single-medication","format":"standard","meta":{"content-type":"","telyrx_subtitle":"Uses, Side Effects, Dosage & FAQs (2026 Guide)","telyrx_last_updated":"2026-04-27T18:00","telyrx_reviewer_name":"Andy Acevedo","telyrx_reviewer_credentials":"PharmD","telyrx_reviewer_job_title":"Pharmacist","telyrx_reviewer_affiliation":"TelyRx","telyrx_reviewer_url":"","telyrx_show_reviewer_job_title":"0","telyrx_show_reviewer_affiliation":"0","telyrx_show_toc":"1","_jetpack_memberships_contains_paid_content":false,"footnotes":"","_telyrx_clean_url":"\/medications\/selenium-sulfide-shampoo\/what-is\/"},"categories":[86],"tags":[],"class_list":["post-8170","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medications"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.2 (Yoast SEO v27.2) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>What Is Selenium Sulfide Shampoo? Uses, Side Effects, Dosage, and FAQs<\/title>\n<meta name=\"description\" content=\"Learn what selenium sulfide shampoo is, how it works, common side effects, and how to get it prescribed online through TelyRx.com\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/telyrx.com\/blog\/medications\/what-is-selenium-sulfide-shampoo\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"What Is Selenium Sulfide Shampoo?\" \/>\n<meta property=\"og:description\" content=\"Learn what selenium sulfide shampoo is, how it works, common side effects, and how to get it prescribed online through TelyRx.com\" \/>\n<meta property=\"og:url\" content=\"https:\/\/telyrx.com\/blog\/medications\/what-is-selenium-sulfide-shampoo\/\" \/>\n<meta property=\"og:site_name\" content=\"TelyRx Blog\" \/>\n<meta property=\"article:published_time\" content=\"2026-04-27T18:00:34+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-04-27T18:00:48+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/telyrx.com\/blog\/wp-content\/uploads\/2026\/04\/selenium_sulfide_shampoo_2.25percent_shampoo_180ml_1_bottle_1907_001_sq-bg_ai_gen_3_4.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"900\" \/>\n\t<meta property=\"og:image:height\" content=\"900\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Mariah Powers\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Mariah Powers\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"7 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/telyrx.com\/blog\/medications\/what-is-selenium-sulfide-shampoo\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/telyrx.com\/blog\/medications\/what-is-selenium-sulfide-shampoo\/\"},\"author\":{\"name\":\"Mariah Powers\",\"@id\":\"https:\/\/telyrx.com\/blog\/#\/schema\/person\/f1042a29c24ab7dd3c5f0fff9a06746b\"},\"headline\":\"What Is Selenium Sulfide Shampoo?\",\"datePublished\":\"2026-04-27T18:00:34+00:00\",\"dateModified\":\"2026-04-27T18:00:34+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/telyrx.com\/blog\/medications\/what-is-selenium-sulfide-shampoo\/\"},\"wordCount\":1328,\"publisher\":{\"@id\":\"https:\/\/telyrx.com\/blog\/#organization\"},\"image\":{\"@id\":\"https:\/\/telyrx.com\/blog\/medications\/what-is-selenium-sulfide-shampoo\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/telyrx.com\/blog\/wp-content\/uploads\/2026\/04\/selenium_sulfide_shampoo_2.25percent_shampoo_180ml_1_bottle_1907_001_sq-bg_ai_gen_3_4.jpg\",\"articleSection\":[\"Medications\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/telyrx.com\/blog\/medications\/what-is-selenium-sulfide-shampoo\/\",\"url\":\"https:\/\/telyrx.com\/blog\/medications\/what-is-selenium-sulfide-shampoo\/\",\"name\":\"What Is Selenium Sulfide Shampoo? 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