{"id":7757,"date":"2026-04-10T14:29:44","date_gmt":"2026-04-10T14:29:44","guid":{"rendered":"https:\/\/telyrx.com\/blog\/?p=7757"},"modified":"2026-04-10T14:29:59","modified_gmt":"2026-04-10T14:29:59","slug":"what-is-dapsone-gel","status":"publish","type":"post","link":"https:\/\/telyrx.com\/blog\/medications\/what-is-dapsone-gel\/","title":{"rendered":"What Is Dapsone Gel?"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\" id=\"h-how-it-works\">How It Works<\/h2>\n\n\n\n<p>Dapsone gel clears acne by working in two ways simultaneously: It has mild antibacterial activity to help reduce the amount of acne-causing germs while also reducing the redness and swelling of the skin.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Mild antibacterial:<\/strong> Dapsone has mild antibacterial activity against bacteria associated with acne. However, it is primarily used for its anti-inflammatory effects rather than as a traditional antibiotic.<\/li>\n\n\n\n<li><strong>Swelling reduction: <\/strong>Dapsone helps reduce inflammation by limiting certain immune cell activity in the skin. This can help decrease redness, swelling, and tenderness in acne lesions.<\/li>\n<\/ul>\n\n\n\n<p>By treating the bacteria and the body&#8217;s overactive reaction to them, dapsone gel helps existing pimples heal faster and prevents new ones from forming.<\/p>\n\n\n\n<div class=\"quick-facts-card\">\n  <table class=\"quick-facts-table\">\n    <colgroup>\n      <col\/>\n      <col\/>\n    <\/colgroup>\n\n    <thead>\n      <tr>\n        <th colspan=\"2\">Quick Facts<\/th>\n      <\/tr>\n    <\/thead>\n\n    <tbody>\n      <tr>\n        <td><strong>Common Brands<\/strong><\/td>\n        <td>Aczone<\/td>\n      <\/tr>\n\n      <tr>\n         <td><strong>Drug Class<\/strong><\/td>\n        <td>Sulfone antibiotic and anti-inflammatory<\/td>\n      <\/tr>\n\n      <tr>\n        <td><strong>Generic Status<\/strong><\/td>\n        <td>Generic version available<\/td>\n      <\/tr>\n\n      <tr>\n         <td><strong>Availability<\/strong><\/td>\n        <td>Prescription only<\/td>\n    <\/tbody>\n  <\/table>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-dosing\">Dosing<\/h2>\n\n\n\n<p>Below are the general dosing guidelines for dapsone gel:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Dapsone 5%:<\/strong> This strength is typically applied as a thin layer to the affected areas two times a day, usually once in the morning and once in the evening.<\/li>\n\n\n\n<li><strong>Dapsone 7.5%:<\/strong> This is a stronger version and is usually applied as a thin layer only once a day.<\/li>\n\n\n\n<li><strong>Application steps:<\/strong> Standard guidelines suggest washing your face with a mild cleanser, then patting it dry before applying the gel. A pea-sized amount is generally enough to cover the entire face.<\/li>\n\n\n\n<li><strong>Consistency:<\/strong> Providers typically recommend completing the full course of medication, even if your skin starts to look clear. It may take up to 12 weeks of daily use to see the full benefits of the treatment.<\/li>\n<\/ul>\n\n\n\n<p><em><strong>Note:<\/strong> Dosing information below is educational only. Your prescribing physician will determine your specific dose based on your individual health needs.\u00a0Always follow your healthcare provider\u2019s instructions for exact dosing.<\/em><\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-uses\">Uses<\/h2>\n\n\n\n<p><strong>FDA-Approved Uses<\/strong><\/p>\n\n\n\n<p>The FDA approves dapsone gel for:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Acne vulgaris:<\/strong> The treatment of both inflammatory (red bumps) and non-inflammatory (blackheads) acne.<\/li>\n<\/ul>\n\n\n\n<p><strong>Off-Label Uses<\/strong><\/p>\n\n\n\n<p>You may see dapsone gel prescribed for uses that are not FDA-approved. This is a common and legal practice called off-label prescribing, where a doctor uses their clinical judgment to prescribe a drug for a different (but well-researched) purpose.<\/p>\n\n\n\n<p>A doctor may prescribe dapsone gel for the following conditions:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Rosacea:<\/strong> Some doctors prescribe dapsone gel to help reduce the red bumps and spots caused by rosacea because it can reduce inflammation.<\/li>\n\n\n\n<li><strong>Hidradenitis suppurativa:<\/strong> In mild cases, it may be used to help manage the painful lumps that can form under the skin.<\/li>\n\n\n\n<li><strong>Perioral dermatitis:<\/strong> This is a red, bumpy rash that appears around the mouth. Some providers use dapsone to help treat it.<\/li>\n<\/ul>\n\n\n<div class=\"telyrx-email-cta alignfull wp-block-telyrx-email-signup\">\n\t<h2 class=\"telyrx-email-cta__heading\" data-toc-hidden=\"true\">Get Savings Updates<\/h2>\n\t<p class=\"telyrx-email-cta__description\">Join our mailing list for exclusive deals and more.<\/p>\n\t\t\t<form\n\t\t\tid=\"telyrx-email-form-1\"\n\t\t\tclass=\"telyrx-email-cta__form\"\n\t\t\tdata-portal-id=\"46401311\"\n\t\t\tdata-form-id=\"14e1d7d5-6b17-4228-b42e-c06d1a6c240b\"\n\t\t\tdata-i18n=\"{&quot;subscribe&quot;:&quot;Subscribe&quot;,&quot;success&quot;:&quot;Thanks! You&#039;re subscribed.&quot;,&quot;error&quot;:&quot;Something went wrong. Please try again.&quot;}\"\n\t\t>\n\t\t\t<div class=\"telyrx-email-cta__pill\">\n\t\t\t\t<input\n\t\t\t\t\ttype=\"email\"\n\t\t\t\t\tname=\"email\"\n\t\t\t\t\tclass=\"telyrx-email-cta__input\"\n\t\t\t\t\tplaceholder=\"Enter your email\"\n\t\t\t\t\trequired\n\t\t\t\t\tautocomplete=\"email\"\n\t\t\t\t\/>\n\t\t\t\t<button type=\"submit\" class=\"telyrx-email-cta__button\">\n\t\t\t\t\tSubscribe\t\t\t\t<\/button>\n\t\t\t<\/div>\n\t\t\t<p class=\"telyrx-email-cta__status\" aria-live=\"polite\"><\/p>\n\t\t<\/form>\n\t\t<noscript>\n\t\t\t<p class=\"telyrx-email-cta__noscript\">Please enable JavaScript to use the signup form.<\/p>\n\t\t<\/noscript>\n\t<\/div>\n\n\n\n<section class=\"telyrx-side-effects\" data-toc-title=\"Side Effects\">\n\t<h2 class=\"telyrx-side-effects__heading\">Side Effects<\/h2>\n\t<hr class=\"telyrx-side-effects__separator\">\n\t<div class=\"telyrx-side-effects__content\">\n\t\t\n\n<p>Most people find that dapsone gel is easy on the skin, but it can cause mild reactions at the application site.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-common-side-effects\">Common Side Effects<\/h3>\n\n\n\n<div class=\"telyrx-side-effects-chip telyrx-side-effects-chip--common\">\n\t\n\n<ul class=\"wp-block-list\">\n<li>Dry or peeling skin<\/li>\n\n\n\n<li>Mild redness or itching<\/li>\n\n\n\n<li>Oily skin or more shine than usual<\/li>\n\n\n\n<li>Headache or common cold symptoms (sinusitis)<\/li>\n<\/ul>\n\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-serious-side-effects\">Serious Side Effects<\/h3>\n\n\n\n<div class=\"telyrx-side-effects-chip telyrx-side-effects-chip--serious\">\n\t\n\n<p>Serious side effects are rare, but it&#8217;s important to know what to look for if they do occur.<\/p>\n\n\n\n<p>It\u2019s generally accepted that you stop taking the medication and immediately call the doctor if you experience any of the following symptoms:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Methemoglobinemia:<\/strong> A rare blood disorder that affects how your body carries oxygen. Symptoms include gray or blue-colored skin or lips, headache, and feeling tired or short of breath.<\/li>\n\n\n\n<li><strong>Red blood cell breakdown:<\/strong> This can happen in people with a condition called G6PD deficiency. Signs include dark urine or yellowing of the skin and eyes.<\/li>\n\n\n\n<li><strong>Severe allergic reactions:<\/strong> It\u2019s generally advised to watch for a bad rash, hives, or swelling of the face and throat.<\/li>\n<\/ul>\n\n<\/div>\n\n\n\n<p class=\"has-muted-color has-text-color\" style=\"font-size:0.875rem\"><em>Call your doctor immediately if you experience any concerning or prolonged symptoms.<\/em><\/p>\n\n\t<\/div>\n<\/section>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-pharmacist-tips\">Pharmacist Tips<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-watch-for-the-orange-effect\">Watch For The Orange Effect<\/h3>\n\n\n\n<p>If you use dapsone gel and benzoyl peroxide together, your skin or facial hair may temporarily turn a yellow-orange color. To prevent this, providers advise using dapsone in the morning and benzoyl peroxide at night, or washing your face well between uses.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-wait-to-moisturize\">Wait To Moisturize<\/h3>\n\n\n\n<p>It is generally recommended to apply the gel to clean skin first. It\u2019s best to let it dry for a minute so it can absorb before applying moisturizer or sunscreen.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-use-on-the-entire-face\">Use On the Entire Face<\/h3>\n\n\n\n<p>Dapsone gel is not a spot treatment for a single pimple. It works best when applied to the entire area every day to prevent new breakouts.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-don-t-mind-the-texture\">Don\u2019t Mind the Texture<\/h3>\n\n\n\n<p>It is normal for dapsone gel to contain tiny particles that feel a little sandy or gritty on your skin. This does not indicate a flaw in the medication.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-avoid-broken-skin\">Avoid Broken Skin<\/h3>\n\n\n\n<p>Avoid applying the gel to cuts, scrapes, or skin that is irritated or raw.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-drug-interactions\">Drug Interactions<\/h2>\n\n\n\n<p>Even though dapsone is a topical medication, it can still interact with other medicines. It\u2019s generally recommended to notify your doctor if you take any of the following medications:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Acne products:<\/strong> Using benzoyl peroxide at the same time can cause temporary orange staining.<\/li>\n\n\n\n<li><strong>Dapsone pills: <\/strong>It\u2019s generally advised<strong> <\/strong>not to use the gel if you are already taking dapsone as an oral medication unless instructed by a healthcare provider.<\/li>\n\n\n\n<li><strong>Other medications: <\/strong>Certain antibiotics or antimalarial medications can increase the risk of rare blood-related side effects.<\/li>\n\n\n\n<li><strong>Acetaminophen: <\/strong>Taking large amounts of acetaminophen (Tylenol) while using dapsone may increase the risk of blood-related issues.<\/li>\n<\/ul>\n\n\n\n<p>Always give your doctor and pharmacist a complete list of all your medications, vitamins, and supplements to check for potential interactions.<\/p>\n\n\n\n<section class=\"telyrx-faq-section\" data-toc-title=\"FAQs\">\n\t<h2 class=\"telyrx-faq-heading\">FAQs<\/h2>\n\t\t<div class=\"telyrx-faq-items\">\n\t\t\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Can I use dapsone gel and benzoyl peroxide in the same skincare routine?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Yes, but it\u2019s generally advised that you do not put them on at the same time. If they mix on your skin, they can cause a temporary orange or yellow stain. Providers typically recommend using dapsone in the morning and your benzoyl peroxide product at night.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">What is the difference between Aczone 5% and Aczone 7.5%?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>The 5% version is the original strength and is typically used twice a day. The 7.5% version is stronger and is typically used once a day.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Is dapsone gel better for painful cystic acne or for blackheads?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Dapsone is used to reduce inflammation, making it suitable for treating red, painful, under-the-skin bumps rather than for blackheads.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Why is this medication frequently prescribed for hormonal acne?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Dapsone is commonly prescribed for hormonal acne because it helps treat deep hormonal breakouts along the jawline without causing the severe peeling or dryness that may come with other acne medications.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Does dapsone gel cause a purge phase?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>No. Most people generally do not experience a purge (where acne gets worse before it gets better) with dapsone gel.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Should I apply my daily moisturizer before or after the dapsone gel?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>It\u2019s generally recommended to apply the dapsone gel first to clean, dry skin so it can reach your pores. Once it has dried, you can apply your moisturizer.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">How long does it typically take for dapsone gel to clear up my acne?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>You might see some improvement in a few weeks, but standard guidelines suggest it takes about 12 weeks of daily use to see results.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Can I safely use salicylic acid or retinoids (like tretinoin) at the same time as dapsone?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Yes. It is common for doctors to prescribe dapsone gel in the morning and a retinoid like tretinoin at night. This treats the acne in two different ways for potentially faster results.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Is it safe to use dapsone gel during pregnancy or while breastfeeding?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>It\u2019s not known whether dapsone gel is safe during pregnancy, so risk cannot be ruled out. However, it is known that it can pass into breast milk and may not be safe for nursing babies. It\u2019s generally advised to talk to your doctor before using it if you are pregnant or nursing.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">How much of the gel am I supposed to apply to my face?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>A pea-sized amount is usually enough to cover your entire face in a thin layer of the gel.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Can I use this strictly as a spot treatment for a single pimple?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>It will not work as well as a spot treatment. Dapsone gel is meant to be applied to the entire area to treat existing pimples and prevent new ones from forming rather than as a spot treatment.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Can I wear foundation or concealer over dapsone gel?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Yes. Dapsone gel dries to a matte finish and can be used under makeup. Let the gel dry and absorb into the skin before applying makeup.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Does dapsone gel help fade red acne scars and dark spots?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Yes. Dapsone gel reduces inflammation, so it can help the red or dark marks left behind by a pimple fade faster.<\/p>\n\n\t<\/div>\n<\/details>\n\n\t<\/div>\n<\/section>\n<script type=\"application\/ld+json\">{\"@context\":\"https:\/\/schema.org\",\"@type\":\"FAQPage\",\"mainEntity\":[{\"@type\":\"Question\",\"name\":\"Can I use dapsone gel and benzoyl peroxide in the same skincare routine?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Yes, but it\u2019s generally advised that you do not put them on at the same time. If they mix on your skin, they can cause a temporary orange or yellow stain. Providers typically recommend using dapsone in the morning and your benzoyl peroxide product at night.\"}},{\"@type\":\"Question\",\"name\":\"What is the difference between Aczone 5% and Aczone 7.5%?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"The 5% version is the original strength and is typically used twice a day. The 7.5% version is stronger and is typically used once a day.\"}},{\"@type\":\"Question\",\"name\":\"Is dapsone gel better for painful cystic acne or for blackheads?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Dapsone is used to reduce inflammation, making it suitable for treating red, painful, under-the-skin bumps rather than for blackheads.\"}},{\"@type\":\"Question\",\"name\":\"Why is this medication frequently prescribed for hormonal acne?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Dapsone is commonly prescribed for hormonal acne because it helps treat deep hormonal breakouts along the jawline without causing the severe peeling or dryness that may come with other acne medications.\"}},{\"@type\":\"Question\",\"name\":\"Does dapsone gel cause a purge phase?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"No. Most people generally do not experience a purge (where acne gets worse before it gets better) with dapsone gel.\"}},{\"@type\":\"Question\",\"name\":\"Should I apply my daily moisturizer before or after the dapsone gel?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"It\u2019s generally recommended to apply the dapsone gel first to clean, dry skin so it can reach your pores. Once it has dried, you can apply your moisturizer.\"}},{\"@type\":\"Question\",\"name\":\"How long does it typically take for dapsone gel to clear up my acne?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"You might see some improvement in a few weeks, but standard guidelines suggest it takes about 12 weeks of daily use to see results.\"}},{\"@type\":\"Question\",\"name\":\"Can I safely use salicylic acid or retinoids (like tretinoin) at the same time as dapsone?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Yes. It is common for doctors to prescribe dapsone gel in the morning and a retinoid like tretinoin at night. This treats the acne in two different ways for potentially faster results.\"}},{\"@type\":\"Question\",\"name\":\"Is it safe to use dapsone gel during pregnancy or while breastfeeding?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"It\u2019s not known whether dapsone gel is safe during pregnancy, so risk cannot be ruled out. However, it is known that it can pass into breast milk and may not be safe for nursing babies. It\u2019s generally advised to talk to your doctor before using it if you are pregnant or nursing.\"}},{\"@type\":\"Question\",\"name\":\"How much of the gel am I supposed to apply to my face?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"A pea-sized amount is usually enough to cover your entire face in a thin layer of the gel.\"}},{\"@type\":\"Question\",\"name\":\"Can I use this strictly as a spot treatment for a single pimple?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"It will not work as well as a spot treatment. Dapsone gel is meant to be applied to the entire area to treat existing pimples and prevent new ones from forming rather than as a spot treatment.\"}},{\"@type\":\"Question\",\"name\":\"Can I wear foundation or concealer over dapsone gel?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Yes. Dapsone gel dries to a matte finish and can be used under makeup. Let the gel dry and absorb into the skin before applying makeup.\"}},{\"@type\":\"Question\",\"name\":\"Does dapsone gel help fade red acne scars and dark spots?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Yes. Dapsone gel reduces inflammation, so it can help the red or dark marks left behind by a pimple fade faster.\"}}]}<\/script>\n\n<div class=\"telyrx-comparable-medications wp-block-telyrx-comparable-medications\">\n\t<h2 class=\"telyrx-comparable-medications__title\">Comparable Medications<\/h2>\n\t\t\t<div class=\"telyrx-comparable-medications__intro\">\n\n<p><strong><strong><strong><strong><strong><strong><strong><strong>Clindamycin, Erythromycin, Winlevi, Benzoyl Peroxide, or Adapalene?<\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/p>\n\n\n\n<p>If side effects or drug interactions are a concern, your doctor may prescribe one of the following alternative medications:<\/p>\n\n<\/div>\n\t\t\t\t<div class=\"telyrx-comparable-medications__item\">\n\t\t\t<div class=\"telyrx-comparable-medications__item-top\">\n\t\t\t\t<div class=\"telyrx-comparable-medications__item-info\">\n\t\t\t\t\t<h3 class=\"telyrx-comparable-medications__name\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"telyrx-comparable-medications__name-link\" href=\"https:\/\/telyrx.com\/medications\/clindamycin-gel\">\n\t\t\t\t\t\t\t\tClindamycin Gel\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/h3>\n\n\t\t\t\t\t\t\t\t\t\t\t<p class=\"telyrx-comparable-medications__price\">\n\t\t\t\t\t\t\tFrom $29.99\t\t\t\t\t\t<\/p>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<a class=\"telyrx-comparable-medications__cta\" href=\"https:\/\/telyrx.com\/medications\/clindamycin-gel\">\n\t\t\t\t\t\tView Product\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<p class=\"telyrx-comparable-medications__description\">\n\t\t\t\t\tThis is a common antibiotic. While it kills bacteria, it lacks the additional anti-inflammatory properties of dapsone gel.\t\t\t\t<\/p>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<hr class=\"telyrx-comparable-medications__divider\">\n\t\t\t\t\t<div class=\"telyrx-comparable-medications__item\">\n\t\t\t<div class=\"telyrx-comparable-medications__item-top\">\n\t\t\t\t<div class=\"telyrx-comparable-medications__item-info\">\n\t\t\t\t\t<h3 class=\"telyrx-comparable-medications__name\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"telyrx-comparable-medications__name-link\" href=\"https:\/\/telyrx.com\/medications\/erythromycin-gel\">\n\t\t\t\t\t\t\t\tErythromycin Gel\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/h3>\n\n\t\t\t\t\t\t\t\t\t\t\t<p class=\"telyrx-comparable-medications__price\">\n\t\t\t\t\t\t\tFrom $48.99\t\t\t\t\t\t<\/p>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<a class=\"telyrx-comparable-medications__cta\" href=\"https:\/\/telyrx.com\/medications\/erythromycin-gel\">\n\t\t\t\t\t\tView Product\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<p class=\"telyrx-comparable-medications__description\">\n\t\t\t\t\tAnother antibiotic used for acne. It is generally considered less effective than dapsone gel for deep, painful bumps.\t\t\t\t<\/p>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<hr class=\"telyrx-comparable-medications__divider\">\n\t\t\t\t\t<div class=\"telyrx-comparable-medications__item\">\n\t\t\t<div class=\"telyrx-comparable-medications__item-top\">\n\t\t\t\t<div class=\"telyrx-comparable-medications__item-info\">\n\t\t\t\t\t<h3 class=\"telyrx-comparable-medications__name\">\n\t\t\t\t\t\t\t\t\t\t\t\t\tClascoterone\t\t\t\t\t\t\t\t\t\t\t<\/h3>\n\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<p class=\"telyrx-comparable-medications__description\">\n\t\t\t\t\tThis is a newer cream that targets the hormones in the skin. Doctors sometimes prescribe both clascoterone and dapsone gel together for a hormonal acne treatment regimen.\t\t\t\t<\/p>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<hr class=\"telyrx-comparable-medications__divider\">\n\t\t\t\t\t<div class=\"telyrx-comparable-medications__item\">\n\t\t\t<div class=\"telyrx-comparable-medications__item-top\">\n\t\t\t\t<div class=\"telyrx-comparable-medications__item-info\">\n\t\t\t\t\t<h3 class=\"telyrx-comparable-medications__name\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"telyrx-comparable-medications__name-link\" href=\"https:\/\/telyrx.com\/medications\/benzoyl-peroxide-topical-wash\">\n\t\t\t\t\t\t\t\tBenzoyl Peroxide Topical Wash\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/h3>\n\n\t\t\t\t\t\t\t\t\t\t\t<p class=\"telyrx-comparable-medications__price\">\n\t\t\t\t\t\t\tFrom $34.99\t\t\t\t\t\t<\/p>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<a class=\"telyrx-comparable-medications__cta\" href=\"https:\/\/telyrx.com\/medications\/benzoyl-peroxide-topical-wash\">\n\t\t\t\t\t\tView Product\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<p class=\"telyrx-comparable-medications__description\">\n\t\t\t\t\tThis helps kill bacteria and clear pores, but it can cause skin dryness and bleach linens like towels. Dapsone gel is generally gentler and will not bleach fabrics.\t\t\t\t<\/p>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<hr class=\"telyrx-comparable-medications__divider\">\n\t\t\t\t\t<div class=\"telyrx-comparable-medications__item\">\n\t\t\t<div class=\"telyrx-comparable-medications__item-top\">\n\t\t\t\t<div class=\"telyrx-comparable-medications__item-info\">\n\t\t\t\t\t<h3 class=\"telyrx-comparable-medications__name\">\n\t\t\t\t\t\t\t\t\t\t\t\t\tAdapalene\t\t\t\t\t\t\t\t\t\t\t<\/h3>\n\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<p class=\"telyrx-comparable-medications__description\">\n\t\t\t\t\tA retinoid that helps with cell turnover. It can help treat blackheads, while dapsone gel is more effective for red, painful bumps. They are commonly used together to treat acne.\t\t\t\t<\/p>\n\t\t\t\t\t<\/div>\n\n\t\t\t<\/div>\n\n\n<div class=\"telyrx-product-list telyrx-product-list--single wp-block-telyrx-product-list\">\n\t\t\t\t\t<a class=\"telyrx-product-list__card telyrx-product-list__card--single\" href=\"https:\/\/telyrx.com\/medications\/dapsone-gel\">\n\t\t\t\t\t\t\t<img\n\t\t\t\t\tclass=\"telyrx-product-list__image\"\n\t\t\t\t\tsrc=\"https:\/\/telyrx.com\/media\/catalog\/product\/d\/a\/dapsonegel_5percent-842_1.png\"\n\t\t\t\t\talt=\"Dapsone Gel\"\n\t\t\t\t\twidth=\"213\"\n\t\t\t\t\theight=\"213\"\n\t\t\t\t\tloading=\"lazy\"\n\t\t\t\t>\n\t\t\t\t\t\t<div class=\"telyrx-product-list__content\">\n\t\t\t\t<p class=\"telyrx-product-list__name\">Dapsone Gel<\/p>\n\t\t\t\t<span class=\"telyrx-product-list__cta telyrx-product-list__cta--yellow\">\n\t\t\t\t\tView Product\t\t\t\t<\/span>\n\t\t\t<\/div>\n\t\t<\/a>\n\t<\/div>\n\n\n<div class=\"telyrx-product-list-section alignfull wp-block-telyrx-product-list\">\n\t<h2 class=\"telyrx-product-list-section__heading\" data-toc-hidden=\"true\">We Have Dapsone Gel in Stock. Get Yours Today!<\/h2>\n\t<div class=\"telyrx-product-list telyrx-product-list--footer-multi\">\n\t\t<div class=\"telyrx-product-list__grid\">\n\t\t\t\t\t\t\t<a class=\"telyrx-product-list__card\" href=\"https:\/\/telyrx.com\/medications\/dapsone-gel\">\n\t\t\t\t\t\t\t\t\t\t\t<img\n\t\t\t\t\t\t\tclass=\"telyrx-product-list__image\"\n\t\t\t\t\t\t\tsrc=\"https:\/\/telyrx.com\/media\/catalog\/product\/d\/a\/dapsonegel_5percent-842_1.png\"\n\t\t\t\t\t\t\talt=\"Dapsone Gel\"\n\t\t\t\t\t\t\twidth=\"213\"\n\t\t\t\t\t\t\theight=\"213\"\n\t\t\t\t\t\t\tloading=\"lazy\"\n\t\t\t\t\t\t>\n\t\t\t\t\t\t\t\t\t\t<div class=\"telyrx-product-list__content\">\n\t\t\t\t\t\t<p class=\"telyrx-product-list__name\">Dapsone Gel<\/p>\n\t\t\t\t\t\t<span class=\"telyrx-product-list__cta telyrx-product-list__cta--yellow\">\n\t\t\t\t\t\t\tOrder Now\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/a>\n\t\t\t\t\t<\/div>\n\t<\/div>\n\t\t\t<div class=\"telyrx-product-list-section__extra\">\n\t\t\t<p class=\"has-muted-color has-text-color has-urbanist-font-family\" style=\"font-size:0.875rem;font-style:italic;font-weight:400;line-height:1.571\"><strong>Important:<\/strong> Information on this page is for educational purposes only. Prescribing decisions are made by independent, licensed providers. TelyRx operates technology-enabled pharmacies and a telehealth platform that connects patients with board-certified licensed providers. Prescriptions, when provider-approved and issued, are filled and shipped by TelyRx-affiliated pharmacies. We do not employ physicians or make prescribing decisions. Learn more about our editorial standards <a href=\"\/blog\/editorial-standards\/\">here<\/a>.<\/p>\t\t<\/div>\n\t<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Dapsone gel, the generic form of Aczone, is a prescription topical medication used to treat acne vulgaris. It belongs to the sulfone class of antibiotics. Dapsone gel offers a different chemical structure than common acne treatments like benzoyl peroxide or clindamycin. This may make it an alternative for patients who find other treatments irritating or ineffective.<\/p>\n<p>Dapsone gel is particularly effective for inflammatory acne, which appears as red, painful bumps rather than only as blackheads or whiteheads.<\/p>\n<p>\nDapsone gel is commonly used for treating hormonal acne, which often presents along the jawline and lower face.<\/p>\n","protected":false},"author":2,"featured_media":7758,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"single-medication","format":"standard","meta":{"content-type":"","telyrx_subtitle":"Uses, Side Effects, Dosage & FAQs (2026 Guide)","telyrx_last_updated":"2026-04-10T14:29","telyrx_reviewer_name":"Ashley Robinson","telyrx_reviewer_credentials":"PharmD","telyrx_reviewer_job_title":"Pharmacy Manager","telyrx_reviewer_affiliation":"TelyRx","telyrx_reviewer_url":"","telyrx_show_reviewer_job_title":"0","telyrx_show_reviewer_affiliation":"0","telyrx_show_toc":"1","footnotes":"","_telyrx_clean_url":"\/medications\/dapsone-gel\/what-is\/"},"categories":[86],"tags":[],"class_list":["post-7757","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medications"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.2 (Yoast SEO v27.2) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>What Is Dapsone Gel? Uses, Side Effects, Dosage, and FAQs<\/title>\n<meta name=\"description\" content=\"Learn what Dapsone Gel is, how it works, common side effects, and how to get it prescribed online through TelyRx.com\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/telyrx.com\/blog\/medications\/what-is-dapsone-gel\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"What Is Dapsone Gel?\" \/>\n<meta property=\"og:description\" content=\"Learn what Dapsone Gel is, how it works, common side effects, and how to get it prescribed online through TelyRx.com\" \/>\n<meta property=\"og:url\" content=\"https:\/\/telyrx.com\/blog\/medications\/what-is-dapsone-gel\/\" \/>\n<meta property=\"og:site_name\" content=\"TelyRx Blog\" \/>\n<meta property=\"article:published_time\" content=\"2026-04-10T14:29:44+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-04-10T14:29:59+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/telyrx.com\/blog\/wp-content\/uploads\/2026\/04\/dapsonegel_5percent-842_1.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"900\" \/>\n\t<meta property=\"og:image:height\" content=\"900\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Mariah Powers\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Mariah Powers\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"7 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/telyrx.com\/blog\/medications\/what-is-dapsone-gel\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/telyrx.com\/blog\/medications\/what-is-dapsone-gel\/\"},\"author\":{\"name\":\"Mariah Powers\",\"@id\":\"https:\/\/telyrx.com\/blog\/#\/schema\/person\/f1042a29c24ab7dd3c5f0fff9a06746b\"},\"headline\":\"What Is Dapsone Gel?\",\"datePublished\":\"2026-04-10T14:29:44+00:00\",\"dateModified\":\"2026-04-10T14:29:44+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/telyrx.com\/blog\/medications\/what-is-dapsone-gel\/\"},\"wordCount\":1365,\"publisher\":{\"@id\":\"https:\/\/telyrx.com\/blog\/#organization\"},\"image\":{\"@id\":\"https:\/\/telyrx.com\/blog\/medications\/what-is-dapsone-gel\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/telyrx.com\/blog\/wp-content\/uploads\/2026\/04\/dapsonegel_5percent-842_1.jpg\",\"articleSection\":[\"Medications\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/telyrx.com\/blog\/medications\/what-is-dapsone-gel\/\",\"url\":\"https:\/\/telyrx.com\/blog\/medications\/what-is-dapsone-gel\/\",\"name\":\"What Is Dapsone Gel? 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