{"id":7719,"date":"2026-04-09T16:52:01","date_gmt":"2026-04-09T16:52:01","guid":{"rendered":"https:\/\/telyrx.com\/blog\/?p=7719"},"modified":"2026-04-09T16:53:47","modified_gmt":"2026-04-09T16:53:47","slug":"what-is-lidocaine","status":"publish","type":"post","link":"https:\/\/telyrx.com\/blog\/medications\/what-is-lidocaine\/","title":{"rendered":"What Is Lidocaine?"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\" id=\"h-how-it-works\">How It Works<\/h2>\n\n\n\n<p>To understand how lidocaine provides relief, it is helpful to look at how your body sends pain signals.&nbsp;<\/p>\n\n\n\n<p>When the lining of your mouth or throat is injured or irritated, nerves in that area send electrical signals to your brain, which you perceive as pain.<\/p>\n\n\n\n<p>Lidocaine works by:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Blocking sodium channels:<\/strong> The medication enters the nerve endings in the mucous membranes and blocks sodium from entering the nerve cells.<\/li>\n\n\n\n<li><strong>Stopping electrical signals:<\/strong> Because sodium is required for nerves to send electrical impulses, blocking these channels prevents the pain signal from starting.<\/li>\n\n\n\n<li><strong>Temporary numbing:<\/strong> By blocking nerve signals in the treated area, lidocaine creates a temporary numbing effect.<\/li>\n<\/ul>\n\n\n\n<p>The onset of relief is typically fast, usually occurring within 3 to 5 minutes of application. The effect is localized, meaning the tissues in contact with the liquid will become numb.<\/p>\n\n\n\n<div class=\"quick-facts-card\">\n  <table class=\"quick-facts-table\">\n    <colgroup>\n      <col\/>\n      <col\/>\n    <\/colgroup>\n\n    <thead>\n      <tr>\n        <th colspan=\"2\">Quick Facts<\/th>\n      <\/tr>\n    <\/thead>\n\n    <tbody>\n      <tr>\n        <td><strong>Common Brands<\/strong><\/td>\n        <td>Glydo (Xylocaine brand is no longer available in the US)<\/td>\n      <\/tr>\n\n      <tr>\n         <td><strong>Drug Class<\/strong><\/td>\n        <td>Topical anesthetic (Amide-type)<\/td>\n      <\/tr>\n\n      <tr>\n        <td><strong>Generic Status<\/strong><\/td>\n        <td>Generic version available<\/td>\n      <\/tr>\n\n      <tr>\n         <td><strong>Availability<\/strong><\/td>\n        <td>Prescription only<\/td>\n    <\/tbody>\n  <\/table>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-dosing\">Dosing<\/h2>\n\n\n\n<p>Correct dosing is vital to prevent too much medication from being absorbed into your system. Providers typically recommend the following:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Standard dose:<\/strong> Use 15 mL (about one tablespoon) of the solution.<\/li>\n\n\n\n<li><strong>Application frequency:<\/strong> Doses are usually spaced at least 3 hours apart.<\/li>\n\n\n\n<li><strong>Maximum limit:<\/strong> It is generally accepted that you should not use more than 8 doses in a 24-hour period.<\/li>\n\n\n\n<li><strong>For mouth pain:<\/strong> Providers recommend swishing the solution around the mouth for 15 to 30 seconds, then spitting it out.<\/li>\n\n\n\n<li><strong>For throat pain:<\/strong> It\u2019s generally advised that you gargle the solution at the back of the throat. You may be told to swallow the liquid only if your doctor instructs you to do so for throat pain relief.<\/li>\n<\/ul>\n\n\n\n<p>Standard guidelines suggest using an accurate measuring device, such as a medicine cup or oral syringe. A household spoon is not an accurate measuring device and may cause you to take the wrong dose.<\/p>\n\n\n\n<p><em><strong>Note:<\/strong> Dosing information below is educational only. Your prescribing physician will determine your specific dose based on your individual health needs.\u00a0Always follow your healthcare provider\u2019s instructions for exact dosing.<\/em><\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-uses\">Uses<\/h2>\n\n\n\n<p><strong>FDA-Approved Uses<\/strong><\/p>\n\n\n\n<p>The FDA approves lidocaine viscous 2% for:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Topical anesthesia:<\/strong> Numbing the mucous membranes of the mouth and throat.<\/li>\n\n\n\n<li><strong>Pain relief:<\/strong> Reducing discomfort from irritated or inflamed oral tissues.<\/li>\n\n\n\n<li><strong>Procedure preparation:<\/strong> Reducing the gag reflex during dental impressions or X-rays.<\/li>\n<\/ul>\n\n\n\n<p><strong>Off-Label Uses<\/strong><\/p>\n\n\n\n<p>Note: You may see lidocaine prescribed for uses that are not FDA-approved. This is a common and legal practice called off-label prescribing, where a doctor uses their clinical judgment to prescribe a drug for a different (but well-researched) purpose.<\/p>\n\n\n\n<p>Lidocaine may be prescribed off-label for the following conditions:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Compound mouthwash:<\/strong> Lidocaine is a common primary ingredient in compounded rinses used to treat oral mucositis (mouth sores) caused by chemotherapy or radiation.<\/li>\n\n\n\n<li><strong>Esophagitis relief:<\/strong> Lidocaine is sometimes used to numb the esophagus in cases of severe acid reflux or irritation, usually under strict medical supervision.<\/li>\n<\/ul>\n\n\n<div class=\"telyrx-email-cta alignfull wp-block-telyrx-email-signup\">\n\t<h2 class=\"telyrx-email-cta__heading\" data-toc-hidden=\"true\">Get Savings Updates<\/h2>\n\t<p class=\"telyrx-email-cta__description\">Join our mailing list for exclusive deals and more.<\/p>\n\t\t\t<form\n\t\t\tid=\"telyrx-email-form-1\"\n\t\t\tclass=\"telyrx-email-cta__form\"\n\t\t\tdata-portal-id=\"46401311\"\n\t\t\tdata-form-id=\"14e1d7d5-6b17-4228-b42e-c06d1a6c240b\"\n\t\t\tdata-i18n=\"{&quot;subscribe&quot;:&quot;Subscribe&quot;,&quot;success&quot;:&quot;Thanks! You&#039;re subscribed.&quot;,&quot;error&quot;:&quot;Something went wrong. Please try again.&quot;}\"\n\t\t>\n\t\t\t<div class=\"telyrx-email-cta__pill\">\n\t\t\t\t<input\n\t\t\t\t\ttype=\"email\"\n\t\t\t\t\tname=\"email\"\n\t\t\t\t\tclass=\"telyrx-email-cta__input\"\n\t\t\t\t\tplaceholder=\"Enter your email\"\n\t\t\t\t\trequired\n\t\t\t\t\tautocomplete=\"email\"\n\t\t\t\t\/>\n\t\t\t\t<button type=\"submit\" class=\"telyrx-email-cta__button\">\n\t\t\t\t\tSubscribe\t\t\t\t<\/button>\n\t\t\t<\/div>\n\t\t\t<p class=\"telyrx-email-cta__status\" aria-live=\"polite\"><\/p>\n\t\t<\/form>\n\t\t<noscript>\n\t\t\t<p class=\"telyrx-email-cta__noscript\">Please enable JavaScript to use the signup form.<\/p>\n\t\t<\/noscript>\n\t<\/div>\n\n\n\n<section class=\"telyrx-side-effects\" data-toc-title=\"Side Effects\">\n\t<h2 class=\"telyrx-side-effects__heading\">Side Effects<\/h2>\n\t<hr class=\"telyrx-side-effects__separator\">\n\t<div class=\"telyrx-side-effects__content\">\n\t\t\n\n<p>While lidocaine is generally well-tolerated when used as directed, it can cause some side effects as the body reacts to the anesthetic.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-common-side-effects\">Common Side Effects<\/h3>\n\n\n\n<div class=\"telyrx-side-effects-chip telyrx-side-effects-chip--common\">\n\t\n\n<ul class=\"wp-block-list\">\n<li>Temporary redness or swelling at the application site<\/li>\n\n\n\n<li>A mild burning or stinging sensation when first applied<\/li>\n\n\n\n<li>Changes in taste or a numb sensation that lasts after the liquid is gone<\/li>\n\n\n\n<li>Dizziness or lightheadedness if too much is absorbed<\/li>\n<\/ul>\n\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-serious-side-effects\">Serious Side Effects<\/h3>\n\n\n\n<div class=\"telyrx-side-effects-chip telyrx-side-effects-chip--serious\">\n\t\n\n<p>Serious side effects are rare, but it&#8217;s important to know what to look for if they do occur.<\/p>\n\n\n\n<p>It\u2019s generally accepted that you stop taking the medication and immediately call the doctor if you experience any of the following symptoms:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Methemoglobinemia:<\/strong> This is a rare blood disorder in which the blood cannot carry enough oxygen. Symptoms include pale or blue-colored skin, headache, fast heartbeat, and shortness of breath.<\/li>\n\n\n\n<li><strong>Systemic toxicity:<\/strong> If too much lidocaine enters the bloodstream, it can cause confusion, tremors, seizures, or a slow heart rate.<\/li>\n\n\n\n<li><strong>Severe allergic reactions:<\/strong> Providers advise watching for hives, swelling of the face or throat, and difficulty breathing.<\/li>\n\n\n\n<li><strong>Aspiration risk:<\/strong> Because the throat becomes numb, patients have an increased risk of choking on food or liquids.<\/li>\n<\/ul>\n\n<\/div>\n\n\n\n<p class=\"has-muted-color has-text-color\" style=\"font-size:0.875rem\"><em>Call your doctor immediately if you experience any concerning or prolonged symptoms.<\/em><\/p>\n\n\t<\/div>\n<\/section>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-pharmacist-tips\">Pharmacist Tips<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-wait-to-eat\">Wait to Eat<\/h3>\n\n\n\n<p>It\u2019s generally advised not to eat or chew gum for at least 60 minutes after using this medication. Numbness in the mouth and throat makes swallowing difficult and increases the risk of biting your tongue or choking.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-shake-the-bottle\">Shake the Bottle<\/h3>\n\n\n\n<p>Before measuring your dose, providers recommend gently shaking the bottle to ensure the lidocaine is evenly mixed throughout the thick liquid.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-target-specific-sores\">Target Specific Sores<\/h3>\n\n\n\n<p>If you have one or two specific canker sores, you can apply the liquid directly to them with a Q-tip or cotton swab, rather than swishing the whole amount.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-store-safely\">Store Safely\u00a0<\/h3>\n\n\n\n<p>Store lidocaine at room temperature.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-check-the-expiration\">Check the Expiration<\/h3>\n\n\n\n<p>Standard guidelines state that the liquid should not be used if it has expired. While it does not need to be refrigerated, it\u2019s best to keep it in a cool, dry place.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-drug-interactions\">Drug Interactions<\/h2>\n\n\n\n<p>Lidocaine can interact with other medications, especially those that affect your heart rhythm or blood oxygen levels.<\/p>\n\n\n\n<p>Let your doctor know if you take:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Heart medications:<\/strong> Use caution if you take antiarrhythmics (medications for irregular heartbeat) or blood pressure pills, such as beta-blockers.<\/li>\n\n\n\n<li><strong>Nitrates:<\/strong> Medications like nitroglycerin may increase the risk of methemoglobinemia when used with lidocaine.<\/li>\n\n\n\n<li><strong>Other anesthetics:<\/strong> Using other numbing products (like benzocaine) at the same time can increase the risk of side effects.<\/li>\n<\/ul>\n\n\n\n<p>Always give your doctor and pharmacist a complete list of all your medications, vitamins, and supplements to check for potential interactions.<\/p>\n\n\n\n<section class=\"telyrx-faq-section\" data-toc-title=\"FAQs\">\n\t<h2 class=\"telyrx-faq-heading\">FAQs<\/h2>\n\t\t<div class=\"telyrx-faq-items\">\n\t\t\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Why should I not eat or drink for at least 60 minutes after using this liquid?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Lidocaine numbs the gag reflex and the muscles used for swallowing. If you eat while numb, you may not be able to clear food from your airway properly, which can lead to choking. Additionally, you may accidentally bite your cheek or tongue because you cannot feel them.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Is it safe to swallow lidocaine, or must I spit it out?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>It\u2019s generally accepted that you only swallow lidocaine if your doctor has instructed you to do so to treat a painful throat. For mouth sores, it is generally recommended to swish and spit to minimize the amount of medication absorbed into your bloodstream.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">How long does the numbing effect actually last after I swish?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>The numbing effect usually begins within a few minutes and typically lasts for about 30 to 60 minutes.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Can I use this liquid lidocaine on a sunburn, bug bite, or open scrape on my skin?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>No. This formulation is used for the wet tissues (mucous membranes) of the mouth and throat. It\u2019s generally accepted that it should not be used on large areas of the skin or on open wounds, as this can lead to dangerous levels of the drug being absorbed into your system.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Is it safe to use this medication if I am pregnant or breastfeeding?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>It is not known if lidocaine can harm an unborn baby, so risk cannot be ruled out. If you are pregnant or breastfeeding, discuss the risks and benefits with your doctor before use.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">How many times a day can I safely use the lidocaine solution without risking an overdose?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Providers advise not exceeding 8 doses in a 24-hour period. Using it more frequently than every 3 hours can cause the medication to build up in your body, increasing the risk of heart and brain side effects.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Does this liquid expire, and does it need to be kept in the refrigerator?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Lidocaine oral solution does expire. Standard guidelines recommend checking the date printed on the bottle or prescription label. It should be stored at room temperature, not in the refrigerator.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Can I apply the liquid directly to a cold sore with a Q-tip instead of swishing it?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Yes. For localized sores, using a Q-tip helps deliver the medication exactly where it is needed and reduces the total amount of drug your body absorbs.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Can I use this solution for a severe toothache or gum infection?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Lidocaine may temporarily numb the surface of the gums, but it will not reach the source of pain inside a tooth. It also does not treat infections. It\u2019s generally advised that you see a dentist for these conditions.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Can I use this liquid to numb my skin before getting a shot or a tattoo?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Standard guidelines advise against this. Viscous lidocaine is not designed to penetrate the outer layer of the skin effectively and is only meant for the lining of the mouth.<\/p>\n\n\t<\/div>\n<\/details>\n\n\n\n<details class=\"telyrx-faq-item\">\n\t<summary class=\"telyrx-faq-question\">\n\t\t<span class=\"telyrx-faq-question-text\">Does this medication interact with blood pressure pills?<\/span>\n\t\t<svg class=\"telyrx-faq-chevron\" width=\"20\" height=\"20\" viewBox=\"0 0 20 20\" fill=\"none\" aria-hidden=\"true\">\n\t\t\t<path d=\"M5 7.5L10 12.5L15 7.5\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n\t\t<\/svg>\n\t<\/summary>\n\t<div class=\"telyrx-faq-answer\">\n\t\t\n\n<p>Lidocaine can interact with certain heart and blood pressure medications, such as propranolol or metoprolol. These drugs can slow down how your liver processes lidocaine, potentially leading to higher levels in your blood.<\/p>\n\n\t<\/div>\n<\/details>\n\n\t<\/div>\n<\/section>\n<script type=\"application\/ld+json\">{\"@context\":\"https:\/\/schema.org\",\"@type\":\"FAQPage\",\"mainEntity\":[{\"@type\":\"Question\",\"name\":\"Why should I not eat or drink for at least 60 minutes after using this liquid?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Lidocaine numbs the gag reflex and the muscles used for swallowing. If you eat while numb, you may not be able to clear food from your airway properly, which can lead to choking. 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Using it more frequently than every 3 hours can cause the medication to build up in your body, increasing the risk of heart and brain side effects.\"}},{\"@type\":\"Question\",\"name\":\"Does this liquid expire, and does it need to be kept in the refrigerator?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Lidocaine oral solution does expire. Standard guidelines recommend checking the date printed on the bottle or prescription label. It should be stored at room temperature, not in the refrigerator.\"}},{\"@type\":\"Question\",\"name\":\"Can I apply the liquid directly to a cold sore with a Q-tip instead of swishing it?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Yes. For localized sores, using a Q-tip helps deliver the medication exactly where it is needed and reduces the total amount of drug your body absorbs.\"}},{\"@type\":\"Question\",\"name\":\"Can I use this solution for a severe toothache or gum infection?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Lidocaine may temporarily numb the surface of the gums, but it will not reach the source of pain inside a tooth. It also does not treat infections. It\u2019s generally advised that you see a dentist for these conditions.\"}},{\"@type\":\"Question\",\"name\":\"Can I use this liquid to numb my skin before getting a shot or a tattoo?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Standard guidelines advise against this. Viscous lidocaine is not designed to penetrate the outer layer of the skin effectively and is only meant for the lining of the mouth.\"}},{\"@type\":\"Question\",\"name\":\"Does this medication interact with blood pressure pills?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Lidocaine can interact with certain heart and blood pressure medications, such as propranolol or metoprolol. These drugs can slow down how your liver processes lidocaine, potentially leading to higher levels in your blood.\"}}]}<\/script>\n\n<div class=\"telyrx-comparable-medications wp-block-telyrx-comparable-medications\">\n\t<h2 class=\"telyrx-comparable-medications__title\">Comparable Medications<\/h2>\n\t\t\t<div class=\"telyrx-comparable-medications__intro\">\n\n<p><strong><strong><strong><strong><strong><strong><strong>Lidocaine 4%, Xylocaine 10%, Benzocaine 20%, Chlorhexidine, or Dexamethasone?<\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/p>\n\n\n\n<p>If side effects or drug interactions are a concern, your healthcare provider may recommend one of the following alternatives:<\/p>\n\n<\/div>\n\t\t\t\t<div class=\"telyrx-comparable-medications__item\">\n\t\t\t<div class=\"telyrx-comparable-medications__item-top\">\n\t\t\t\t<div class=\"telyrx-comparable-medications__item-info\">\n\t\t\t\t\t<h3 class=\"telyrx-comparable-medications__name\">\n\t\t\t\t\t\t\t\t\t\t\t\t\tLidocaine 4% solution\t\t\t\t\t\t\t\t\t\t\t<\/h3>\n\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<p class=\"telyrx-comparable-medications__description\">\n\t\t\t\t\tA thinner and more concentrated liquid commonly used as a spray by doctors before medical procedures. The 2% viscous form is typically preferred for home use because its thickness helps it coat the mouth.\t\t\t\t<\/p>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<hr class=\"telyrx-comparable-medications__divider\">\n\t\t\t\t\t<div class=\"telyrx-comparable-medications__item\">\n\t\t\t<div class=\"telyrx-comparable-medications__item-top\">\n\t\t\t\t<div class=\"telyrx-comparable-medications__item-info\">\n\t\t\t\t\t<h3 class=\"telyrx-comparable-medications__name\">\n\t\t\t\t\t\t\t\t\t\t\t\t\tXylocaine 10% oral spray\t\t\t\t\t\t\t\t\t\t\t<\/h3>\n\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<p class=\"telyrx-comparable-medications__description\">\n\t\t\t\t\tA highly concentrated spray used primarily in dental or surgical settings to provide rapid numbing before a procedure.\t\t\t\t<\/p>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<hr class=\"telyrx-comparable-medications__divider\">\n\t\t\t\t\t<div class=\"telyrx-comparable-medications__item\">\n\t\t\t<div class=\"telyrx-comparable-medications__item-top\">\n\t\t\t\t<div class=\"telyrx-comparable-medications__item-info\">\n\t\t\t\t\t<h3 class=\"telyrx-comparable-medications__name\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"telyrx-comparable-medications__name-link\" href=\"https:\/\/telyrx.com\/medications\/chlorhexidine-oral-rinse\">\n\t\t\t\t\t\t\t\tChlorhexidine Oral Rinse\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/h3>\n\n\t\t\t\t\t\t\t\t\t\t\t<p class=\"telyrx-comparable-medications__price\">\n\t\t\t\t\t\t\tFrom $35.99\t\t\t\t\t\t<\/p>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<a class=\"telyrx-comparable-medications__cta\" href=\"https:\/\/telyrx.com\/medications\/chlorhexidine-oral-rinse\">\n\t\t\t\t\t\tView Product\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<p class=\"telyrx-comparable-medications__description\">\n\t\t\t\t\tAn antibacterial mouthwash used to treat gum disease. It does not provide numbing or pain relief but targets the underlying bacterial cause of certain types of mouth irritation.\t\t\t\t<\/p>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<hr class=\"telyrx-comparable-medications__divider\">\n\t\t\t\t\t<div class=\"telyrx-comparable-medications__item\">\n\t\t\t<div class=\"telyrx-comparable-medications__item-top\">\n\t\t\t\t<div class=\"telyrx-comparable-medications__item-info\">\n\t\t\t\t\t<h3 class=\"telyrx-comparable-medications__name\">\n\t\t\t\t\t\t\t\t\t\t\t\t\tDexamethasone oral rinse\t\t\t\t\t\t\t\t\t\t\t<\/h3>\n\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<p class=\"telyrx-comparable-medications__description\">\n\t\t\t\t\tA prescription steroid liquid used to reduce inflammation and swelling of mouth sores.\t\t\t\t<\/p>\n\t\t\t\t\t<\/div>\n\n\t\t\t<\/div>\n\n\n<div class=\"telyrx-product-list telyrx-product-list--single wp-block-telyrx-product-list\">\n\t\t\t\t\t<a class=\"telyrx-product-list__card telyrx-product-list__card--single\" href=\"https:\/\/telyrx.com\/medications\/lidocaine\">\n\t\t\t\t\t\t\t<img\n\t\t\t\t\tclass=\"telyrx-product-list__image\"\n\t\t\t\t\tsrc=\"https:\/\/telyrx.com\/media\/catalog\/product\/l\/i\/lidocaine_100ml2_1.png\"\n\t\t\t\t\talt=\"Lidocaine\"\n\t\t\t\t\twidth=\"213\"\n\t\t\t\t\theight=\"213\"\n\t\t\t\t\tloading=\"lazy\"\n\t\t\t\t>\n\t\t\t\t\t\t<div class=\"telyrx-product-list__content\">\n\t\t\t\t<p class=\"telyrx-product-list__name\">Lidocaine<\/p>\n\t\t\t\t<span class=\"telyrx-product-list__cta telyrx-product-list__cta--yellow\">\n\t\t\t\t\tView Product\t\t\t\t<\/span>\n\t\t\t<\/div>\n\t\t<\/a>\n\t<\/div>\n\n\n<div class=\"telyrx-product-list-section alignfull wp-block-telyrx-product-list\">\n\t<h2 class=\"telyrx-product-list-section__heading\" data-toc-hidden=\"true\">We Have Lidocaine in Stock. Get Yours Today!<\/h2>\n\t<div class=\"telyrx-product-list telyrx-product-list--footer-multi\">\n\t\t<div class=\"telyrx-product-list__grid\">\n\t\t\t\t\t\t\t<a class=\"telyrx-product-list__card\" href=\"https:\/\/telyrx.com\/medications\/lidocaine\">\n\t\t\t\t\t\t\t\t\t\t\t<img\n\t\t\t\t\t\t\tclass=\"telyrx-product-list__image\"\n\t\t\t\t\t\t\tsrc=\"https:\/\/telyrx.com\/media\/catalog\/product\/l\/i\/lidocaine_100ml2_1.png\"\n\t\t\t\t\t\t\talt=\"Lidocaine\"\n\t\t\t\t\t\t\twidth=\"213\"\n\t\t\t\t\t\t\theight=\"213\"\n\t\t\t\t\t\t\tloading=\"lazy\"\n\t\t\t\t\t\t>\n\t\t\t\t\t\t\t\t\t\t<div class=\"telyrx-product-list__content\">\n\t\t\t\t\t\t<p class=\"telyrx-product-list__name\">Lidocaine<\/p>\n\t\t\t\t\t\t<span class=\"telyrx-product-list__cta telyrx-product-list__cta--yellow\">\n\t\t\t\t\t\t\tOrder Now\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/a>\n\t\t\t\t\t<\/div>\n\t<\/div>\n\t\t\t<div class=\"telyrx-product-list-section__extra\">\n\t\t\t<p class=\"has-muted-color has-text-color has-urbanist-font-family\" style=\"font-size:0.875rem;font-style:italic;font-weight:400;line-height:1.571\"><strong>Important:<\/strong> Information on this page is for educational purposes only. Prescribing decisions are made by independent, licensed providers. TelyRx operates technology-enabled pharmacies and a telehealth platform that connects patients with board-certified licensed providers. Prescriptions, when provider-approved and issued, are filled and shipped by TelyRx-affiliated pharmacies. We do not employ physicians or make prescribing decisions. Learn more about our editorial standards <a href=\"\/blog\/editorial-standards\/\">here<\/a>.<\/p>\t\t<\/div>\n\t<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Lidocaine oral solution, the generic form of Viscous Xylocaine, is a topical anesthetic medication. It is formulated as a thick liquid to help coat the mucous membranes of the mouth and throat. It is used to treat pain caused by conditions such as:<\/p>\n<ul>\n<li>Canker sores or cold sores<\/li>\n<li>Mouth and throat irritation following dental work or medical procedures<\/li>\n<li>Severe sore throat (pharyngitis)<\/li>\n<li>Stomatitis (inflammation of the mouth lining)<\/li>\n<\/ul>\n<p>Lidocaine is an amide-type local anesthetic. It is available by prescription only and is intended for topical use, providing relief where applied. Unlike oral pain tablets, which are absorbed throughout your system, viscous lidocaine works locally to dull pain in the immediate area.<\/p>\n","protected":false},"author":2,"featured_media":7720,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"single-medication","format":"standard","meta":{"content-type":"","telyrx_subtitle":"Uses, Side Effects, Dosage & FAQs (2026 Guide)","telyrx_last_updated":"2026-04-09T16:52","telyrx_reviewer_name":"Ashley Robinson","telyrx_reviewer_credentials":"PharmD","telyrx_reviewer_job_title":"Pharmacy Manager","telyrx_reviewer_affiliation":"TelyRx","telyrx_reviewer_url":"","telyrx_show_reviewer_job_title":"0","telyrx_show_reviewer_affiliation":"0","telyrx_show_toc":"1","footnotes":"","_telyrx_clean_url":"\/medications\/lidocaine\/what-is\/"},"categories":[86],"tags":[],"class_list":["post-7719","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medications"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.2 (Yoast SEO v27.2) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>What Is Lidocaine? 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