Amlodipine/Olmesartan Tablets
Amlodipine/olmesartan tablets are a combination medicine used to lower high blood pressure. They work by relaxing blood vessels in two ways: amlodipine helps widen the arteries by blocking calcium, and olmesartan prevents a hormone called angiotensin II from tightening blood vessels. Together, they make it easier for blood to flow, reducing strain on the heart and lowering the risk of serious problems like stroke or heart attack.
- Combination of a calcium channel blocker (amlodipine) and an angiotensin II receptor blocker (olmesartan)
- Typically taken once daily, with or without food, at the same time each day
- Grapefruit juice may increase amlodipine levels and should be avoided
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Amlodipine/Olmesartan Tablets Medication Description
Amlodipine/olmesartan tablets combine two antihypertensive agents with complementary mechanisms to achieve better blood pressure control. Amlodipine, a dihydropyridine calcium channel blocker, relaxes vascular smooth muscle by reducing calcium entry, leading to arterial dilation and decreased peripheral resistance. Olmesartan, an angiotensin II receptor blocker (ARB), prevents angiotensin II from binding to its receptor, reducing vasoconstriction and aldosterone-mediated sodium retention. Together, these actions lower blood pressure more effectively than monotherapy, making this combination useful for patients who require multiple agents to reach target goals. This medication is generally reserved for patients who do not achieve adequate control with a single drug or who benefit from combination therapy from the start. It is taken orally once daily and is well tolerated in most patients. However, clinicians must consider contraindications such as pregnancy and monitor for potential adverse effects like hypotension, renal impairment, or peripheral edema. Amlodipine/olmesartan plays an important role in comprehensive cardiovascular risk management, often alongside lifestyle changes and other therapies. -
Amlodipine/Olmesartan Tablets Side Effects
Common side effects include dizziness, headache, flushing, and swelling of the ankles or feet. Some patients may experience fatigue or mild gastrointestinal discomfort. Serious side effects are rare but can include very low blood pressure, worsening kidney function, or severe allergic reactions. Patients should seek immediate medical attention if they notice chest pain, fainting, or signs of swelling in the face or throat. Regular monitoring and adherence to prescribed dosing help minimize risks and ensure safe, effective treatment. -
Consumer Information Use and Disclaimer
This information should not be used to decide whether or not to take this medicine or any other medicine. Only a healthcare provider has the knowledge and training to decide which medicines are right for you. TelyRx does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a limited summary of general information about the medicine’s uses from the patient education materials and is not intended to be comprehensive. This limited summary does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not intended to provide medical advice, diagnosis or treatment and does not replace information you may receive from your healthcare provider. For a more detailed summary of information about the risks and benefits of using this medicine, please review the entire patient education information you receive with the medication.
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